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Vertex Pharmaceuticals Announces the Date of its Fourth Quarter and Full Year 2006 Financial Results Conference Call and Webcast

    CAMBRIDGE, Mass., Jan. 16 /PRNewswire-FirstCall/ -- Vertex
Pharmaceuticals Incorporated (Nasdaq: VRTX) will announce its fourth
quarter and full year 2006 financial results on Thursday, February 1, 2007
after the financial markets close. The Company will host a conference call
at 5:00 p.m. EST.
    The conference call will be webcast live and may be accessed from the
'Events Calendar' of Vertex's website at http://www.vrtx.com. A replay of the
conference call and webcast will be archived on the Company's website until
February 15, 2007. To ensure a timely connection, it is recommended that
users register at least 15 minutes prior to the scheduled webcast.
    About Vertex
    Vertex Pharmaceuticals Incorporated is a global biotechnology company
committed to the discovery and development of breakthrough small molecule
drugs for serious diseases. The Company's strategy is to commercialize its
products both independently and in collaboration with major pharmaceutical
companies. Vertex's product pipeline is focused on viral diseases,
inflammation, autoimmune diseases, cancer, pain and bacterial infection.
Vertex co-discovered the HIV protease inhibitor, Lexiva, with
GlaxoSmithKline.
    Lexiva is a registered trademark of the GlaxoSmithKline group of
companies.
    Vertex's press releases are available at http://www.vrtx.com.

    Vertex Contact:
    Lora Pike, Manager, Investor Relations, (617)-444-6755


SOURCE Vertex Pharmaceuticals Incorporated




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    CONTACT:
    Lora Pike, Manager, Investor Relations of
    Vertex Pharmaceuticals Incorporated, +1-617-444-6755