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Pfizer Achieves Key 2006 Financial Targets

  - Full-Year 2006 Revenues Grew 2 Percent to $48.4 Billion, Key Products
     Substantially Attained Targets, Nine Exceeded $1 Billion in Sales
  - Full-Year 2006 Reported Diluted EPS Increased to $2.66, Which Included
 Significant Gain From Sale of Consumer Healthcare Business; Full-Year 2006
              Adjusted Diluted EPS(1) Grew 6 Percent to $2.06
 - During Quarter, Pfizer Submitted U.S. Regulatory Filings for Lyrica for
  Fibromyalgia and for Maraviroc, Four Product Candidates Entered Phase 3
                                  Testing
   - Company to Discuss Key Strategies and Plans at Analyst Meeting This
                                 Afternoon
 ($ billions, except per-share amounts) Fourth Quarter Full Year 2006 2005
                                 2006 2005
 Revenues $12.603 $12.547 $48.371 $47.405 Reported Net Income $9.449 $2.732
    $19.337 $8.085 Reported Diluted EPS $1.32 $0.37 $2.66 $1.09 Adjusted
Income(1) $3.047 $3.591 $14.982 $14.469 Adjusted Diluted EPS(1) $0.43 $0.49
         $2.06 $1.95 [see end of text prior to tables for footnote]

    NEW YORK, Jan. 22 /PRNewswire-FirstCall/ -- Pfizer Inc today announced
that revenues for full-year 2006 increased 2 percent, reported diluted EPS
grew 144 percent, and adjusted diluted EPS(1) grew 6 percent versus 2005.
Revenues in the fourth quarter of 2006 were substantially unchanged,
reported diluted EPS grew 257 percent, and adjusted diluted EPS(1)
decreased 12 percent versus the comparable quarter in 2005.
    "In the face of many challenges in 2006, we substantially achieved a
number of financial targets that we set early in the year," said Pfizer
Chairman and Chief Executive Officer Jeffrey B. Kindler. "We took decisive
action and delivered solid performance despite challenges, including the
significant revenue impact due to the loss of exclusivity of Zithromax and
Zoloft in the U.S. We achieved revenue growth of 2 percent for the year. We
delivered adjusted diluted EPS(1) of $2.06, in line with our upwardly
revised guidance.
    "While we attained nearly all of our financial targets for the year, we
continue to face a difficult operating environment, including competitive
challenges and the risks inherent in drug development. Our decision to
discontinue development of torcetrapib/atorvastatin in early December 2006
was disappointing and brought into sharper focus the need to transform
Pfizer over time to succeed in a dynamic healthcare marketplace. We are
reviewing every aspect of our business, and I look forward to discussing
our priorities when we meet with analysts in New York later today," Mr.
Kindler concluded.
    "During the fourth quarter of 2006, we strengthened our commitment to
enhancing total return to shareholders," said Vice Chairman David Shedlarz.
"We completed the divestiture of the Consumer Healthcare business in the
quarter, receiving approximately $16.6 billion in proceeds. Combined with
projected strong cash flow from operations over the next several years,
these proceeds will be used to make key investments in new products and
technologies and to support a strong dividend and an active share purchase
program.
    "In December 2006, Pfizer announced a 21-percent increase in its first-
quarter 2007 dividend to 29 cents per share. This significant increase
builds on a 26-percent dividend increase in 2006. Pfizer has now increased
its dividend every year for 40 consecutive years, and in the past 10 years
the company's dividend has increased on average 18 percent per year. The
company also continued its substantial share purchase program by buying
$2.5 billion of its common stock in the fourth quarter of 2006. Pfizer
purchased $7.0 billion of common stock during 2006. During the past five
years, Pfizer has purchased more than $35 billion of its common stock."
        Pfizer's Pharmaceutical Operations Substantially Meet Targets
                           for Key In-Line Products
    "Worldwide pharmaceutical 2006 revenues met our expectations," said Ian
Read, President of Worldwide Pharmaceutical Operations. "We focused on the
top-line growth of key in-line medicines, including Lipitor, Celebrex,
Lyrica, and Geodon, and we launched Sutent, Eraxis, Chantix, and Exubera in
the U.S."
    Worldwide pharmaceutical revenues were $45.1 billion for full-year
2006, a 2-percent increase compared to full-year 2005. In the U.S.,
revenues increased 4 percent for the full-year 2006 compared to the same
period in 2005. A strong performance in the U.S. was driven by growth from
several of our core products, including Lipitor (up 6 percent), Celebrex
(up 24 percent), Geodon (up 31 percent), Norvasc (up 13 percent), Xalatan
(up 12 percent), Zyrtec (up 15 percent), Detrol (up 14 percent), Zyvox (up
20 percent), Vfend (up 27 percent), Aromasin (up 34 percent), and Caduet
(up 95 percent), as well as the successful launches of several new
medicines.
    Worldwide pharmaceutical operations substantially met the sales targets
established at the beginning of the year for several key brands.
Notwithstanding our original sales target of more than $13 billion for
Lipitor, actual sales totaled $12.886 billion, representing 6-percent
growth -- a substantial accomplishment in the face of intense branded and
generic competition in the statin market. For Celebrex, sales of $2.039
billion exceeded our original goal of achieving sales of more than $2
billion, demonstrating that we are on our way to rebuilding physician and
patient confidence in this important medicine. Worldwide sales of $1.156
billion for Lyrica significantly exceeded both the initial target of more
than $900 million and the subsequent, raised target of more than $1
billion, a performance that establishes Lyrica as one of the most
successful pharmaceutical market entries in recent years. Geodon reached
$758 million in worldwide revenues, just short of our target of about $800
million. Nine Pfizer products surpassed $1 billion in sales in 2006, with
Detrol and Lyrica joining this list for the first time.
    Pharmaceutical revenues for the fourth quarter of 2006 were $11.7
billion worldwide, comparable to those in the fourth quarter of 2005, and
were $6.1 billion in the U.S., down 3 percent, mainly reflecting the loss
of exclusivity of Zoloft in the U.S. in June 2006. Worldwide sales of
Celebrex, Geodon, and Lyrica in the fourth quarter of 2006 grew 15 percent,
32 percent, and 131 percent, respectively.
                    New Products Continue to Gain Momentum
    2006 was an exciting year of product launches. Against an original
target of six new-product entries in the U.S., we launched four products --
Eraxis, Sutent, Exubera, and Chantix. In Europe, Sutent and Exubera entered
the marketplace, and Champix (the trade name for Chantix in Europe) was
launched beginning in December 2006. Several key medicines received
approval for new indications in 2006, including approvals of Lyrica for
central neuropathic pain and generalized anxiety disorder in the EU, and
Celebrex for juvenile rheumatoid arthritis in the U.S.
                  Progress Achieved in New-Product Pipeline
    "We continued to advance the candidates in our pipeline during the
fourth quarter of 2006," said Dr. John LaMattina, President, Pfizer Global
Research and Development. Maraviroc, our CCR5 receptor antagonist to treat
HIV infection, was submitted for approval in the U.S. and EU in December
2006. Maraviroc has been accepted for filing and granted an accelerated
review in the EU.
    A supplemental NDA filing for Lyrica in the treatment of fibromyalgia
was submitted to the FDA on December 20, 2006. Fibromyalgia is
characterized by chronic, widespread pain that affects tens of millions of
people worldwide, predominantly women. It is frequently accompanied by
disturbed sleep, anxious mood, and poor quality of life. Pfizer is excited
about Lyrica as a potential breakthrough for patients for treatment in this
area and expects approval and launch of this new indication in the U.S. in
the second half of 2007.
    Four new programs advanced into Phase 3 during the quarter:

    -- Axitinib, our next-generation anti-angiogenesis agent to treat thyroid
       cancer,
    -- CP-945,598, our cannabinoid-1 antagonist to treat obesity and its
       devastating complications,
    -- Sutent for the treatment of metastatic breast cancer, and
    -- Zithromax/chloroquine to treat malaria, the single greatest killer of
       children in Africa.
    Pfizer recently provided more detail on its pipeline than ever before
with the launch of an on-line site for tracking development compounds
across Pfizer's largest-ever pipeline. This new website, launched last
month, will be updated twice a year and is available at
http://www.pfizer.com/pipeline.
                Pfizer Achieves Full-Year 2006 Financial Goals
    In reviewing full-year 2006 results, Alan Levin, chief financial
officer, said, "Pfizer delivered adjusted diluted EPS(1) of $2.06 for the
full year, in line with our most recent guidance and representing growth of
6 percent compared to full-year 2005 adjusted diluted EPS(1) of $1.95.
Adjusted diluted EPS(1) was well ahead of our original 2006 guidance of
about $1.93 (restated to reflect the sale of our Consumer Healthcare
business) due in part to greater savings associated with our broad-based
Adapting to Scale (AtS) productivity program (savings of approximately $2.6
billion for the full year versus our original goal of about $2 billion), a
lower effective tax rate, and fewer shares outstanding given increased
share purchases. Reported diluted EPS of $2.66 included a one-time gain of
$1.08 ($7.9 billion) associated with the recently completed divestiture of
Pfizer Consumer Healthcare (PCH), among other factors.
    "For the fourth quarter of 2006, adjusted diluted EPS(1) of $.43
declined by 12 percent relative to the comparable period in 2005,
reflecting the timing of certain operating expenses in 2006. The cost of
sales pre-tax component of adjusted income(1) in the quarter increased by
11 percent, reflecting the timing of implementation of inventory management
initiatives, the impact of foreign exchange, and charges related to certain
asset writedowns. The R&D pre-tax component of adjusted income(1) in the
quarter grew by 22 percent, reflecting timing considerations associated
with the advancement of development programs for pipeline products,
expenditures associated with in- licensing of a new compound, and the
establishment of various research collaborations with third parties, among
other factors. Reported net income of $9.4 billion for the fourth quarter
included a gain of $7.9 billion on the sale of our Consumer Healthcare
business, as well as purchase-accounting- related charges, costs associated
with our expanded AtS productivity initiative, and a $320 million charge
related to the impairment of intangible assets associated with
Depo-Provera, a contraceptive product.
    "We will discuss our forward-looking financial guidance during this
afternoon's analyst meeting," Mr. Levin concluded.
    For additional details, please see the attached financial schedules,
product revenue tables, supplemental financial information, and Disclosure
Notice.
    (1) "Adjusted income" and "adjusted diluted earnings per share (EPS)" are
        defined as reported net income and reported diluted EPS excluding
        purchase-accounting adjustments, acquisition-related costs,
        discontinued operations, cumulative effect of a change in accounting
        principles, and certain significant items.  As described under
        Adjusted Income in the Management's Discussion and Analysis of
        Financial Condition and Results of Operations section of Pfizer's Form
        10-Q for the quarterly period ended October 1, 2006, management uses
        adjusted income, among other factors, to set performance goals and to
        measure the performance of the overall company.  We believe that
        investors' understanding of our performance is enhanced by disclosing
        this measure.  Reconciliations of fourth-quarter and full-year 2006
        and 2005 adjusted income and adjusted diluted EPS to reported net
        income and reported diluted EPS, as well as a reconciliation of the
        original $1.93 estimate of full-year 2006 adjusted diluted EPS to
        reported diluted EPS, are provided in the materials accompanying this
        report.  The adjusted income and adjusted diluted EPS measures are
        not, and should not be viewed as, substitutes for U.S. GAAP net income
        and diluted EPS.



                       PFIZER INC AND SUBSIDIARY COMPANIES
                        CONSOLIDATED STATEMENTS OF INCOME
                                   (UNAUDITED)

    (millions of dollars, except per common share data)

                           Fourth Quarter   % Incr./      Full Year   % Incr./
                           2006      2005    (Decr.)   2006      2005  (Decr.)

     Revenues            $12,603    $12,547     -    $48,371   $47,405     2
     Costs and expenses:
      Cost of sales(a)     2,217      1,982    12      7,640     7,232     6
      Selling,
       informational and
       administrative
       expenses(a)         4,562      4,356     5     15,589    15,313     2
      Research and
       development
       expenses(a)         2,412      1,970    22      7,599     7,256     5
      Amortization of
       intangible assets     815        830    (2)     3,261     3,399    (4)
      Acquisition-related
       in-process
       research and
       development
       charges               322          -     *        835     1,652   (49)
      Restructuring
       charges and
       acquisition-
       related costs         507        573   (12)     1,323     1,356    (2)
      Other
       (income)/deductions
       -- net                 54       (306)    *       (904)      397     *
     Income from
      continuing
      operations before
      provision for
      taxes on income,
      minority interests
      and cumulative
      effect of a
      change in
      accounting
      principles           1,714      3,142   (45)    13,028    10,800    21
     Provision for taxes
      on income              223        536   (58)     1,992     3,178   (37)
     Minority interests        2          6   (65)        12        12     4
     Income from
      continuing
      operations before
      cumulative
      effect of a change
      in accounting
      principles           1,489      2,600   (43)    11,024     7,610    45
     Discontinued
      operations:
      Income from
       discontinued
       operations -- net
       of tax                103        152   (32)       433       451    (4)
      Gains on sales of
       discontinued
       operations -- net
       of tax              7,857          3    M+      7,880        47    M+
     Discontinued
      operations -- net
      of tax               7,960        155    M+      8,313       498    M+
     Income before
      cumulative effect
      of a change in
      accounting
      principles           9,449      2,755   243     19,337     8,108   138
     Cumulative effect of
      a change in
      accounting
      principles -- net
      of tax                   -        (23)    *          -       (23)    *
     Net income           $9,449     $2,732   246    $19,337    $8,085   139
     Earnings per common
      share - Basic:
      Income from
       continuing
       operations before
       cumulative
       effect of a change
       in accounting
       principles          $0.21      $0.35   (40)     $1.52     $1.03    48
      Discontinued
       operations -- net
       of tax               1.11       0.02    M+       1.15      0.07    M+
      Income before
       cumulative effect
       of a change in
       accounting
       principles           1.32       0.37   257       2.67      1.10   143
      Cumulative effect
       of a change in
       accounting
       principles              -          -     -          -         -     -
      Net income           $1.32      $0.37   257      $2.67     $1.10   143
     Earnings per common
      share - Diluted:
      Income from
       continuing
       operations before
       cumulative
       effect of a change
       in accounting
       principles          $0.21      $0.35   (40)     $1.52     $1.02    49
      Discontinued
       operations -- net
       of tax               1.11       0.02    M+       1.14      0.07    M+
      Income before
       cumulative effect
       of a change in
       accounting
       principles           1.32       0.37   257       2.66      1.09   144
      Cumulative effect
       of a change in
       accounting
       principles              -          -     -          -         -     -
      Net income           $1.32      $0.37   257      $2.66     $1.09   144
     Weighted-average
      shares used to
      calculate earnings
      per common share:
      Basic                7,144      7,327            7,242     7,361
      Diluted              7,171      7,368            7,274     7,411


    (a) Exclusive of amortization of intangible assets, except as discussed in
        footnote 4 below.

     *  Calculation not meaningful.

     M+ Change greater than one-thousand percent.
     Certain amounts and percentages may reflect rounding adjustments.

    1.  The above financial statement presents the three-month and twelve-
        month periods ended December 31 of each year.  Subsidiaries operating
        outside the United States are included for the three-month and twelve-
        month periods ended November 30 of each year.
    2.  In December 2006, we sold our Consumer Healthcare business for
        approximately $16.6 billion.  The above financial statement reflects
        this business as discontinued operations for all periods through
        December 20, 2006, including our international subsidiaries.
    3.  As required, the estimated value of Acquisition-related in-process
        research and development charges(IPR&D) is expensed at acquisition
        date. In 2006, we expensed $835 million of IPR&D, of which $322
        million related to our acquisition of PowderMed Ltd. in the fourth
        quarter and $513 million primarily related to our acquisition of Rinat
        Neurosciences Corp. in the second quarter. In 2005, we expensed $1.7
        billion of IPR&D, of which $1.4 billion related to our acquisition of
        Vicuron Pharmaceuticals, Inc in the third quarter and $262 million
        related primarily to our acquisition of Idun Pharmaceuticals, Inc. in
        the second quarter.
    4.  Amortization expense related to acquired intangible assets that
        contribute to our ability to sell, manufacture, research, market and
        distribute our products are included in Amortization of intangible
        assets as they benefit multiple business functions. Amortization
        expense related to acquired intangible assets that are associated with
        a single function are included in Cost of sales, Selling,
        informational and administrative expenses or Research and development
        expenses, as appropriate.
    5.  Other (income)/deductions -- net for the fourth quarter and full year
        2006 includes a charge of $320 million related to the impairment of
        the Depo-Provera intangible asset and, for the full year 2005,
        includes a charge of $1.2 billion related to the impairment of the
        Bextra intangible asset.
    6.  Discontinued operations -- net of tax is primarily related to our
        Consumer Healthcare business.
    7.  Provision for taxes on income in the full year 2006 includes a
        downward revision ($124 million) of the estimated tax costs related to
        repatriation of foreign earnings in 2005 and tax benefits associated
        with the resolution of certain tax positions ($441 million).  Full
        year 2005 includes tax benefits associated with the resolution of
        certain tax positions ($586 million) and a tax provision related to
        the repatriation of foreign earnings of $1.7 billion.



                     PFIZER INC AND SUBSIDIARY COMPANIES
  RECONCILIATION FROM REPORTED NET INCOME AND REPORTED DILUTED EARNINGS PER
       SHARE TO ADJUSTED INCOME AND ADJUSTED DILUTED EARNINGS PER SHARE
                                   (UNAUDITED)

    (millions of dollars, except per common share data)

                              Fourth Quarter % Incr./    Full Year    % Incr./
                              2006      2005  (Decr.)  2006     2005   (Decr.)

    Reported net income      $9,449   $2,732   246    $19,337   $8,085   139
    Purchase accounting
     adjustments -- net of
     tax                        899      569    58      3,131    3,967   (21)
    Acquisition-related
     costs -- net of tax          5      214   (98)        14      599   (98)
    Discontinued operations
     -- net of tax           (7,960)    (155)   M+     (8,313)    (498)   M+
    Cumulative effect of a
     change in accounting
     principles -- net of tax     -       23     *          -       23     *
    Certain significant
     items -- net of tax        654      208   214        813    2,293   (65)
    Adjusted income          $3,047   $3,591   (15)   $14,982  $14,469     4

    Reported diluted
     earnings per common
     share                    $1.32    $0.37   257      $2.66    $1.09   144
    Purchase accounting
     adjustments -- net of
     tax                       0.13     0.08    63       0.43     0.54   (20)
    Acquisition-related
     costs -- net of tax          -     0.03     *          -     0.08     *
    Discontinued operations
     -- net of tax            (1.11)   (0.02)   M+      (1.14)   (0.07)   M+
    Cumulative effect of a
     change in accounting
     principles -- net of tax     -        -     *          -        -     *
    Certain significant
     items -- net of tax       0.09     0.03   200       0.11     0.31   (65)
    Adjusted diluted
     earnings per common
     share                    $0.43    $0.49   (12)     $2.06    $1.95     6


    *   Calculation not meaningful.
    M+  Change greater than one thousand percent.
    Certain amounts and percentages may reflect rounding adjustments.

    1. The above reconciliation presents the three-month and twelve-month
       periods ended December 31 of each year.  Subsidiaries operating outside
       the United States are included for the three-month and twelve-month
       periods ended November 30 of each year.
    2. Adjusted income and Adjusted diluted earnings per common share as shown
       above reflect the following items:


      (millions of dollars)                   Fourth Quarter      Full Year
                                               2006     2005    2006     2005
      Purchase accounting adjustments:
         In-process research and
          development charges(a)                $322     $-      $835  $1,652
         Intangible amortization and
          other(b)                               806    802     3,220   3,289
         Total purchase accounting
          adjustments, pre-tax                 1,128    802     4,055   4,941
         Income taxes                           (229)  (233)     (924)   (974)
                  Total purchase accounting
                   adjustments -- net of tax     899    569     3,131   3,967
      Acquisition-related costs:
         Integration costs(c)                     13    159        21     543
         Restructuring charges(c)                 (1)   149         6     375
         Total acquisition-related costs,
          pre-tax                                 12    308        27     918
         Income taxes                             (7)   (94)      (13)   (319)
                 Total acquisition-related
                  costs -- net of tax              5    214        14     599
      Discontinued operations:
         Income from discontinued
          operations(d)                         (150)  (230)     (643)   (695)
         Gains on sales of discontinued
          operations(d)                      (10,206)    (5)  (10,243)    (77)
         Total discontinued operations,
          pre-tax                            (10,356)  (235)  (10,886)   (772)
         Income taxes                          2,396     80     2,573     274
                  Total discontinued
                   operations -- net of tax   (7,960)  (155)   (8,313)   (498)
      Cumulative effect of a change in
       accounting principles -- net of tax         -     23         -      23
      Certain significant items:
         Asset impairment charges and
          other associated costs(e)              320     24       320   1,240
         Sanofi-aventis research and
          development milestone(f)                 -      -      (118)      -
         Restructuring charges - Adapting
          to Scale(c)                            495    265     1,296     438
         Implementation costs - Adapting
          to Scale(g)                            241    192       788     325
         Gain on disposals of investments
          and other(h)                           (13)  (134)     (173)   (134)
         Total certain significant items,
          pre-tax                              1,043    347     2,113   1,869
         Income taxes                           (389)  (104)     (735)   (654)
         Resolution of certain tax
          positions(i)                             -      -      (441)   (586)
         Tax impact for the repatriation
          of foreign earnings(i)                   -    (35)     (124)  1,664
                 Total certain significant
                  items -- net of tax            654    208       813   2,293

      Total purchase accounting
       adjustments, acquisition-related
       costs, discontinued operations,
       cumulative effective of a change
       in accounting principles and certain
       significant items -- net of tax       $(6,402)  $859   $(4,355) $6,384

      (a) Included in Acquisition-related in-process research and development
          charges.
      (b) Included primarily in Amortization of intangible assets.
      (c) Included in Restructuring charges and acquisition-related costs.
      (d) Discontinued operations -- net of tax is primarily related to our
          Consumer Healthcare business.
      (e) Included primarily in Other (income)/deductions -- net. For the
          fourth quarter and full year 2006, includes $320 million related to
          the impairment of the Depo-Provera intangible asset, and for the
          full year 2005, includes $1.2 billion related to the impairment of
          the Bextra intangible asset.
      (f) Included in Research and development expenses.
      (g) Included in Cost of sales ($114 million), Selling, informational and
          administrative expenses ($83 million) and Research and development
          expenses ($44 million) for the three months ended December 31, 2006
          and included in Cost of sales ($392 million), Selling, informational
          and administrative expenses ($243 million), Research and development
          expenses ($176 million) and in Other (income)/deductions-net ($23
          million income) for the full year ended December 31, 2006.  Included
          in Cost of sales ($87 million), Selling, informational and
          administrative expenses ($75 million) and Research and development
          expenses ($30 million) for the three months ended December 31, 2005
          and included in Cost of sales ($124 million), Selling, informational
          and administrative expenses ($151 million), Research and development
          expenses ($50 million) for the full year ended December 31, 2005.
      (h) Included in Other (income)/deductions -- net.
      (i) Included in Provision for taxes on income.



                                  PFIZER INC
                           SEGMENT/PRODUCT REVENUES
                             FOURTH QUARTER 2006
                            (millions of dollars)

                        WORLDWIDE             U.S.           INTERNATIONAL
                                   %                    %                  %
                  2006     2005   Chg   2006    2005   Chg   2006  2005   Chg

    TOTAL
    REVENUES     12,603  12,547    -    6,404  6,609   (3)  6,199  5,938    4

    PHARMA-
    CEUTICAL     11,666  11,653    -    6,055  6,246   (3)  5,611  5,407    4

    - CARDIOVASCULAR
      AND
      METABOLIC
      DISEASES    5,243   5,068    3    2,865  2,787    3   2,378  2,281    4

      LIPITOR     3,335   3,357   (1)   1,945  2,069   (6)  1,390  1,288    8
      NORVASC     1,317   1,244    6      686    613   12     631    631    -
      CARDURA       140     146   (4)       2      2   35     138    144   (4)
      CADUET        115      65   77      109     63   71       6      2  333
      ACCUPRIL/
      ACCURETIC      68      44   56        5    (25)(122)     63     69   (9)
      CHANTIX/
      CHAMPIX        68       -    *       68      -    *       -      -    *

    - CENTRAL
      NERVOUS
      SYSTEM
      DISORDERS   1,251   1,673  (25)     597  1,023  (42)    654    650    1

      ZOLOFT        166     808  (79)      76    653  (88)     90    155  (42)
      LYRICA        353     153  131      214     82  160     139     71   98
      GEODON/
      ZELDOX        210     159   32      176    131   34      34     28   24
      NEURONTIN     120     141  (15)      18     27  (34)    102    114  (11)
      ARICEPT**      98      90    9        -      -    *      98     90    8
      XANAX/
      XR             81     102  (21)      15     35  (59)     66     67   (1)
      RELPAX         81      63   27       52     38   38      29     25   11

    - ARTHRITIS
      AND PAIN      737     650   13      477    402   19     260    248    5

      CELEBREX      540     472   15      412    357   16     128    115   12

    - INFECTIOUS
      AND
      RESPIRATORY
      DISEASES      866   1,111  (22)     256    513  (50)    610    598    2

      ZYVOX         223     164   36      144    118   22      79     46   70
      ZITHROMAX/
      ZMAX          109     402  (73)      (3)   262 (101)    112    140  (20)
      VFEND         148     112   31       49     40   23      99     72   36
      DIFLUCAN      109     128  (15)     (13)    (1)  M+     122    129   (5)

    - UROLOGY       754     727    4      429    410    5     325    317    3

      VIAGRA        450     430    5      222    212    5     228    218    5
      DETROL/
      DETROL LA     290     283    2      201    193    5      89     90   (3)

    - ONCOLOGY      641     497   29      273    167   64     368    330   11

      CAMPTOSAR     235     237   (1)     127    124    3     108    113   (4)
      ELLENCE        76      94  (20)      11     17  (33)     65     77  (17)
      AROMASIN       91      71   29       30     25   23      61     46   33
      SUTENT        104       -    *       69      -    *      35      -    *

    - OPHTHALMOLOGY 396     362    9      123    116    6     273    246   11

      XALATAN/
      XALACOM       391     361    8      123    116    6     268    245    9

    - ENDOCRINE
      DISORDERS     261     266   (2)      67     86  (23)    194    180    7

      GENOTROPIN    209     204    3       61     60    2     148    144    3

    - ALL OTHER   1,127     991   14      746    559   33     381    432  (11)

      ZYRTEC/
      ZYRTEC D      374     327   14      374    327   14       -      -    *

    - ALLIANCE
      REVENUE
      (Aricept,
      Macugen,
      Mirapex,
      Olmetec,
      Rebif and
      Spiriva)      390     308   26      222    183   21     168    125   34

    ANIMAL
    HEALTH          655     630    4      281    283   (1)    374    347    8

    OTHER ***       282     264    7       68     80  (15)    214    184   16

    *   - Calculation not meaningful.
    **  - Represents direct sales under license agreement with Eisai Co.,
           Ltd.
    *** - Includes Capsugel and Pfizer CenterSource.
    M+  - Change greater than one-thousand percent.
    Certain amounts and percentages may reflect rounding adjustments.
    Certain prior year data have been reclassified to conform to the
    current year presentation.



                                  PFIZER INC
                           SEGMENT/PRODUCT REVENUES
                              TWELVE MONTHS 2006
                            (millions of dollars)

                       WORLDWIDE                U.S.         INTERNATIONAL
                                  %                     %                  %
                  2006    2005   Chg    2006   2005    Chg  2006   2005   Chg
    TOTAL
    REVENUES     48,371  47,405    2   25,822 24,751    4  22,549 22,654    -

    PHARMA-
    CEUTICAL     45,083  44,269    2   24,503 23,471    4  20,580 20,798   (1)

    - CARDIOVASCULAR
      AND
      METABOLIC
      DISEASES   19,871  18,732    6   11,124 10,036   11   8,747  8,696    1

      LIPITOR    12,886  12,187    6    7,849  7,401    6   5,037  4,786    5
      NORVASC     4,866   4,706    3    2,500  2,222   13   2,366  2,484   (5)
      CARDURA       538     586   (8)       7      7    -     531    579   (8)
      CADUET        370     185   99      349    179   95      21      6  241
      ACCUPRIL/
      ACCURETIC     266     294  (10)      29     22   37     237    272  (13)
      CHANTIX/
      CHAMPIX       101       -    *      101      -    *       -      -    *

    - CENTRAL
      NERVOUS
      SYSTEM
      DISORDERS   6,038   6,391   (6)   3,635  3,816   (5)  2,403  2,575   (7)

      ZOLOFT      2,110   3,256  (35)   1,752  2,573  (32)    358    683  (47)
      LYRICA      1,156     291  297      717    111   M+     439    180  144
      GEODON/
      ZELDOX        758     589   29      631    483   31     127    106   20
      NEURONTIN     496     639  (22)      91    159  (43)    405    480  (16)
      ARICEPT**     358     346    4        1      -    *     357    346    4
      XANAX/XR      316     409  (23)      70    141  (50)    246    268   (8)
      RELPAX        286     233   23      185    143   30     101     90   11

    - ARTHRITIS
      AND PAIN    2,711   2,386   14    1,781  1,377   29     930  1,009   (8)

      CELEBREX    2,039   1,730   18    1,577  1,267   24     462    463    -

    - INFECTIOUS
      AND
      RESPIRATORY
      DISEASES    3,474   4,770  (27)   1,222  2,449  (50)  2,252  2,321   (3)

      ZYVOX         782     618   27      527    438   20     255    180   42
      ZITHROMAX/
      ZMAX          638   2,025  (69)     210  1,497  (86)    428    528  (19)
      VFEND         515     397   30      178    140   27     337    257   31
      DIFLUCAN      435     498  (13)     (17)   (17)  (3)    452    515  (12)

    - UROLOGY     2,809   2,684    5    1,586  1,497    6   1,223  1,187    3

      VIAGRA      1,657   1,645    1      796    802   (1)    861    843    2
      DETROL/
      DETROL LA   1,100     988   11      769    675   14     331    313    5

    - ONCOLOGY    2,191   1,996   10      887    701   26   1,304  1,295    1

      CAMPTOSAR     903     910    -      491    471    4     412    439   (6)
      ELLENCE       312     367  (15)      54     73  (26)    258    294  (12)
      AROMASIN      320     247   30      113     85   34     207    162   27
      SUTENT        219       -    *      167      -    *      52      -    *

    - OPHTHAL-
      MOLOGY      1,461   1,373    6      483    432   12     978    941    4

      XALATAN/
      XALACOM     1,453   1,372    6      483    432   12     970    940    3

    - ENDOCRINE
      DISORDERS     985   1,049   (6)     258    341  (24)    727    708    3

      GENOTROPIN    795     808   (2)     230    239   (4)    565    569   (1)

    - ALL OTHER   4,169   3,823    9    2,711  2,205   23   1,458  1,618  (10)

      ZYRTEC/
      ZYRTEC D    1,569   1,362   15    1,569  1,362   15       -      -    *

    - ALLIANCE
      REVENUE
      (Aricept,
      Macugen,
      Mirapex,
      Olmetec,
      Rebif and
      Spiriva)    1,374   1,065   29      816    617   32     558    448   25

    ANIMAL
    HEALTH        2,311   2,206    5    1,032    993    4   1,279  1,213    5

    OTHER ***       977     930    5      287    287    -     690    643    7


     *   - Calculation not meaningful.
     **  - Represents direct sales under license agreement with Eisai Co.,
           Ltd.
     *** - Includes Capsugel and Pfizer CenterSource.

     M+  - Change greater than one-thousand percent.
     Certain amounts and percentages may reflect rounding adjustments.
     Certain prior year data have been reclassified to conform to the current
     year presentation.

                                  PFIZER INC
                      SUPPLEMENTAL FINANCIAL INFORMATION

    1) Revenue Growth
    Fourth-quarter 2006 revenues were substantially unchanged and full-year
2006 revenues increased 2% compared to the same periods in 2005, due
primarily to the solid aggregate performance of our broad portfolio of
patent-protected medicines and an aggregate year-over-year increase in
revenues from new products launched in 2004, 2005, and 2006, largely offset
by the impact of the loss of U.S. exclusivity on Zoloft in June 2006, as
well as on Zithromax in November 2005.
    Revenues in the fourth quarter of 2006 were also impacted by the
weakening of the U.S. dollar relative to many foreign currencies
(especially the euro), which increased revenue by $164 million. Revenues
for the full-year of 2006 were impacted by the strengthening of the U.S.
dollar relative to many foreign currencies (especially the euro and
Japanese yen), which decreased revenue by $279 million.
    2) Change in Cost of Sales
    The Cost of Sales pre-tax component of adjusted income(1) increased 11%
in the fourth quarter and 3% for the full year of 2006 compared to the same
periods in 2005. Reported cost of sales increased 12% in the fourth quarter
of 2006 and increased 6% for the full year of 2006 compared to the same
periods in 2005. The increase in the fourth quarter primarily reflects the
timing of implementation of inventory management initiatives, the impact of
foreign exchange, and charges related to certain asset writedowns.
Full-year cost of sales growth reflects these same considerations,
partially offset by the impact of changes in 2006 sales mix during the
first half of the year and the realization of savings associated with our
Adapting to Scale (AtS) productivity initiatives, among other factors. In
addition, cost of sales includes charges of $114 million and $87 million
related to our AtS productivity initiative for the fourth quarter of 2006
and 2005, and $392 million and $124 million for the twelve months ended
December 31, 2006 and 2005.
    3) Change in Selling, Informational & Administrative (SI&A) Expenses
and Research & Development (R&D) Expenses
    SI&A expenses increased 5% and 2% in the fourth quarter and full year
of 2006, compared to the same periods in 2005.
    R&D expenses, excluding acquisition-related in-process research and
development charges (IPR&D), grew 22% and 5% in the fourth quarter and full
year of 2006 compared to the same periods in 2005. The increases reflect
timing considerations associated with the advancement of development
programs for pipeline products, expenditures associated with in-licensing
of a new compound, and the establishment of various research collaborations
with third parties, among other factors. IPR&D charges of $322 million
primarily related to the acquisition of PowderMed Ltd. were recorded in the
fourth quarter of 2006. Full-year 2006 IPR&D charges were $835 million,
primarily related to the acquisition of PowderMed, Ltd. and Rinat
Neuroscience Corp. In full-year 2005, we recorded IPR&D charges of $1.4
billion for the acquisition of Vicuron Pharmaceuticals, Inc., as well as
$262 million, related primarily to our acquisition of Idun Pharmaceuticals
Inc.
    SI&A and R&D expenses include charges of $83 million and $44 million
related to AtS implementation costs in the fourth quarter of 2006, and $243
million and $176 million in the full year of 2006. SI&A and R&D expenses
included charges of $75 million and $30 million related to AtS
implementation costs in the three months ended December 31, 2005, and $151
million and $50 million in the twelve months of 2005.
    4) Savings and Costs Relating to Productivity Initiatives
    Our Adapting to Scale (AtS) productivity initiative, launched in the
first quarter of 2005, involves a comprehensive, multi-year review of our
processes, organizations, systems, and decision making to identify and
capitalize on opportunities to make the company more effective and
efficient. Savings realized during 2006 were approximately $2.6 billion for
the full year of 2006, exceeding our original goal of about $2.0 billion
for the year.
    Costs relating to the AtS productivity initiative were $736 million and
$2.1 billion for the fourth quarter and full year of 2006, compared to $457
million and $763 million in the fourth quarter and full year of 2005.
Fourth- quarter and full-year 2006 costs included a provision for
reductions in the U.S. pharmaceutical field force.
    5) Other Income and Other Deductions


    ($ millions)                Fourth Quarter               Full Year
                              2006         2005*         2006        2005*

    Net Interest (Income)/
     Expense                 $(160)       $(110)       $(437)       $(269)
    Asset Impairment Charges   320            7          320        1,159

    Royalties                 (117)         (87)        (395)        (320)

    Gains on Disposals of
     Investments/ Product
     Lines                      (9)        (114)        (233)        (172)

    Other, Net                  20           (2)        (159)          (1)

    Other (Income)/Deductions
    -Net                       $54        $(306)       $(904)        $397


    * Certain 2005 amounts were reclassified to conform to the 2006
      presentation.

    In the fourth quarter of 2006, we recorded a charge of $320 million
related to the impairment of our Depo-Provera intangible asset.  In connection
with the decision to suspend sales of Bextra in the first quarter of 2005, we
recorded a charge of $1.1 billion relating to the impairment of our Bextra
intangible asset.

    6) Effective Tax Rate


                            Fourth Quarter          Full Year

    2005 Reported(a)            17.1%                  29.4%(c)

    2005 Adjusted(a)(b)         21.8%                  21.8%

    2006 Reported(a)            13.0%(d)               15.3%(e)

    2006 Adjusted(a)(b)         21.7%(f)               22.0%(f)


    (a) 2005 and 2006 Reported and Adjusted are based on income from
        continuing operations and therefore exclude the results of our
        divested Consumer Healthcare business.
    (b) Used in the calculation of Adjusted income(1).
    (c) The reported tax rate in 2005 reflects tax costs associated with
        our program in 2005 to repatriate foreign earnings under the
        American Jobs Creation Act; the impact of a $1.4 billion charge
        for acquired IPR&D, which is not deductible for tax purposes; and
        the favorable resolution of certain tax positions.
    (d) The reported tax rate for the fourth quarter of 2006 reflects the
        retroactive reenactment of the R&D tax credit in the U.S. in
        December 2006, the full amount of which was recorded in the
        fourth quarter of 2006.
    (e) The reported tax rate for full-year 2006 reflects the favorable
        resolution of certain tax positions, a favorable tax-law change
        in the first quarter, a downward revision of the estimated tax
        costs related to the repatriation of foreign earnings in 2005,
        the retroactive reenactment of the R&D tax credit in the U.S. in
        December 2006, and the impact of the sale of our Consumer
        Healthcare business, among other factors.
    (f) The fourth-quarter and full-year 2006 effective tax rate on
        Adjusted income(1) benefited from the retroactive reenactment of the
        R&D tax credit in the U.S. in December 2006.  The full amount of
        this benefit was recorded in the fourth quarter of 2006.
    7) Reconciliation of Original* Forecasted 2006 Adjusted Income(1) and
Adjusted Diluted EPS(1) to Original* Forecasted 2006 Reported Net Income
and Reported Diluted EPS
                                                   Full Year 2006 Original*
                                                          Forecast
    ($ billions, except per-share amounts)        Net Income(a) Diluted EPS(a)
    Income/(Expense)
    Forecasted Adjusted Income/Diluted EPS(1)         ~$14.5         ~$1.93
    Purchase Accounting Impacts, Net of Tax            (2.3)         (0.31)
    Adapting-to-Scale Costs, Net of Tax            (1.4 - 1.7)  (0.19 - 0.23)
    Income From Discontinued Operations,
     Net of Tax(b)                                      0.5           0.07
    Resolution of Certain Tax Positions                 0.4           0.06
    Forecasted Reported Net Income/Diluted
     EPS                                        ~ $11.4 - $11.7 ~$1.52 - $1.56


    * Adapted from forecast disclosed on Form 8-K, filed on February 10,
      2006.

    (a) Forecasts in the table exclude the effects of business-
        development transactions not completed as of December 31, 2005.
        Forecasts in the table do not include the potential impact from a
        substantial prospective gain on the divestiture of our Consumer
        Healthcare business, as well as costs related to our recently
        announced sales-force restructuring.
    (b) Primarily reflects the reclassification of our Consumer
        Healthcare business to discontinued operations.

    8) Consumer Healthcare
    We completed the sale of our Consumer Healthcare business on December
20, 2006. Revenues from our Consumer Healthcare business were $1.1 billion
and $4.0 billion for the fourth quarter and full year of 2006,
respectively. Income from discontinued operations -- net of tax, was $8.3
billion for the full year of 2006, including the fourth-quarter gain on
sale of our Consumer Healthcare business of $7.9 billion.
    9) Share-Purchase Program
    In total, the Company purchased approximately 266 million shares at a
total cost of about $7 billion during 2006, including about 94 million
shares (about $2.5 billion) in the fourth quarter. In June 2006, the Board
of Directors increased our share-purchase authorization from $5 billion to
$18 billion.
    (1) "Adjusted income" and "adjusted diluted earnings per share (EPS)"
        are defined as reported net income and reported diluted EPS
        excluding purchase-accounting adjustments, acquisition-related
        costs, discontinued operations, cumulative effect of a change in
        accounting principles and certain significant items.  As
        described under Adjusted Income in the Management's Discussion
        and Analysis of Financial Condition and Results of Operations
        section of Pfizer's Form 10-Q for the quarterly period ended
        October 1, 2006, management uses adjusted income, among other
        factors, to set performance goals and to measure the performance
        of the overall company.  We believe that investors' understanding
        of our performance is enhanced by disclosing this measure.
        Reconciliations of fourth-quarter and full-year 2006 and 2005
        adjusted income and adjusted diluted EPS to reported net income
        and reported diluted EPS as well as a reconciliation of the
        original $1.93 estimate of full-year 2006 adjusted diluted EPS to
        reported diluted EPS, are provided in the materials accompanying
        this report.  The adjusted income and adjusted diluted EPS
        measures are not, and should not be viewed as, substitutes for U.S.
        GAAP net income and diluted EPS.
    DISCLOSURE NOTICE: The information contained in this document and the
attachments is as of January 22, 2007. The Company assumes no obligation to
update any forward-looking statements contained in this document or the
attachments as a result of new information or future events or
developments.
    This document and the attachments contain forward-looking information
about the Company's financial results and estimates, business plans and
prospects, in-line products, and product candidates that involve
substantial risks and uncertainties. You can identify these statements by
the fact that they use words such as "will," "anticipate," "estimate,"
"expect," "project," "intend," "plan," "believe," "target," "forecast", and
other words and terms of similar meaning in connection with any discussion
of future operating or financial performance or business plans and
prospects. Among the factors that could cause actual results to differ
materially are the following: the success of research and development
activities; decisions by regulatory authorities regarding whether and when
to approve our drug applications as well as their decisions regarding
labeling and other matters that could affect the availability or commercial
potential of our products; the speed with which regulatory authorizations,
pricing approvals, and product launches may be achieved; the success of
external business development activities; competitive developments,
including with respect to competitor drugs and drug candidates that treat
diseases and conditions similar to those treated by our in-line drugs and
drug candidates; the ability to successfully market both new and existing
products domestically and internationally; difficulties or delays in
manufacturing; trade buying patterns; the ability to meet generic and
branded competition after the loss of patent protection for our products
and competitor products; the impact of existing and future regulatory
provisions on product exclusivity; trends toward managed care and health
care cost containment; possible U.S. legislation or regulatory action
affecting, among other things, pharmaceutical pricing and reimbursement,
including under Medicaid and Medicare, the importation of prescription
drugs that are marketed outside the U.S. and sold at prices that are
regulated by governments of various foreign countries, and the involuntary
approval of prescription medicines for over-the-counter use; the impact of
the Medicare Prescription Drug, Improvement and Modernization Act of 2003;
legislation or regulations in markets outside the U.S. affecting product
pricing, reimbursement, or access; contingencies related to actual or
alleged environmental contamination; claims and concerns that may arise
regarding the safety or efficacy of in-line products and product
candidates; legal defense costs, insurance expenses, settlement costs, and
the risk of an adverse decision or settlement related to product liability,
patent protection, governmental investigations, ongoing efforts to explore
various means for resolving asbestos litigation, and other legal
proceedings; the Company's ability to protect its patents and other
intellectual property both domestically and internationally; interest rate
and foreign currency exchange rate fluctuations; governmental laws and
regulations affecting domestic and foreign operations, including tax
obligations; changes in generally accepted accounting principles; any
changes in business, political, and economic conditions due to the threat
of future terrorist activity in the U.S. and other parts of the world, and
related U.S. military action overseas; growth in costs and expenses;
changes in our product, segment, and geographic mix; and the impact of
acquisitions, divestitures, restructurings, product withdrawals, and other
unusual items, including our ability to realize the projected benefits of
our Adapting to Scale multi-year productivity initiative, including the
projected benefits of the broadening of this initiative over the next few
years. A further list and description of these risks, uncertainties, and
other matters can be found in the Company's Annual Report on Form 10-K for
the fiscal year ended December 31, 2005, and in its reports on Forms 10-Q
and 8-K.
    This document may include discussion of certain clinical studies
relating to various in-line products and/or product candidates. These
studies typically are part of a larger body of clinical data relating to
such products or product candidates, and the discussion herein should be
considered in the context of the larger body of data.


SOURCE Pfizer Inc




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