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Immunex Reports Financial Results for 2000

  Record Financial Performance Positions Immunex for Growth - Sales Up 60%,
                   Profits Up 248% and Cash at $1.6 Billion

    SEATTLE, Jan. 24 /PRNewswire/ -- Immunex Corporation (Nasdaq: IMNX) today
reported net income of $154.4 million for the year ending December 31, 2000,
or 28 cents per share, on revenues of $861.8 million.  This record-setting
performance for the company reflects significant growth over 1999 results,
when the company posted net income of $44.3 million, or 8 cents per share, on
revenues of $541.7 million.
    For the three months ending December 31, 2000, Immunex reported net income
of $49.2 million, or 9 cents per share, on revenues of $250.7 million,
compared to net income of $16.2 million, or 3 cents per share, on revenues of
$162.6 million for the same period in 1999.  Also during the quarter, a note
for $450 million held by American Home Products Corporation (NYSE: AHP) was
converted to Immunex common stock.
    For the year, the company generated positive cash flow from operations of
$171.9 million.  Cash and marketable securities at December 31, 2000 totaled
$1.6 billion, due largely to the successful completion of an equity offering
that netted Immunex proceeds in excess of $770 million.
    Total product sales for the year grew 60 percent, to $828.8 million in
2000 from $519.3 million in 1999.
    "Record product sales have allowed Immunex to increase investments in
research and development to create the next generation of innovative medicines
for patients, and new value for our shareholders," said Immunex chairman and
chief executive officer, Ed Fritzky.  "In 2001, we expect to advance products
forward in seven disease areas, including clinical trials for the first time
of two new molecules:  IL-1 receptor type 2 in inflammation and TRAIL/Apo2
ligand in cancer.  Ending the year with $1.6 billion in cash, we are well
positioned to capitalize on our many opportunities for future value creation."
    Sales of ENBREL(R) (etanercept), a leading biologic treatment for
rheumatoid arthritis, increased 78 percent to $652.4 million in 2000, its
second full year on the market.
    "At the launch of ENBREL, we set a sales goal of $500 million for its
third year, and sales of ENBREL in its second year of over $650 million have
far exceeded that goal," said Peggy Phillips, Immunex chief operating officer.
"This demand demonstrates both the value ENBREL can bring to patients, and why
we are expanding capacity as rapidly as possible -- to make ENBREL available
for all patients who are candidates for therapy. In addition, we are pleased
to announce that ENBREL has received an updated indication and is now the only
biologic treatment indicated for first-line use to inhibit the progression of
structural damage in patients with moderately to severely active rheumatoid
arthritis."
    Fourth quarter 2000 sales of ENBREL totaled $194.1 million, a gain of
65 percent over the same period in 1999 and 13 percent over the third quarter
of 2000.   As earlier announced, this strong demand for ENBREL has reached the
company's current manufacturing capacity.  To help ensure that patients
already using ENBREL have uninterrupted access, the company has registered
over 70,000 patients in the ENBREL Enrollment Program to continue to receive
the medicine.  Immunex has also established a queue system for new patients.
New patients who enroll in the program will receive supply when it becomes
available.  A manufacturing facility in Rhode Island is now being retrofit to
produce ENBREL in 2002 and, assuming regulatory approval, should potentially
double the supply.
    The company's specialty therapeutics product line posted an overall
increase of 18 percent over 1999 levels. For the year 2000, net sales of the
immune system modulator LEUKINE(R) (sargramostim) grew 28 percent over 1999 to
$88.3 million.  Net sales of NOVANTRONE(R) (mitoxantrone for injection
concentrate) totaled $59.9 million, an increase of 35 percent over 1999.
NOVANTRONE was approved by the U.S. Food and Drug Administration for a new use
during the fourth quarter 2000, to treat worsening forms of multiple
sclerosis.
    Research and development expenses totaled $166.7 million for the year,
compared to $126.7 million in 1999, reflecting a range of new investments in
research and product collaborations to expand and accelerate the company's new
product pipeline.
    "Immunex agreements with Celera, Abgenix and Cambridge Antibody Technology
this year have broadened our research capabilities with the latest genomics
tools, and created a comprehensive strategy for development of fully human
therapeutic monoclonal antibodies," stated Doug Williams, Ph.D., Immunex chief
technology officer.  "Moreover, our new process science facility opens new
pathways for moving more Immunex and collaborator molecules into clinical
trials, faster."
    Selling, general and administrative (SG&A) expenses totaled
$344.4 million, up from $216.7 million in 1999.  SG&A expenses include
profit-sharing payments to co-promotion partner Wyeth-Ayerst for ENBREL.
Wyeth-Ayerst is the pharmaceutical division of American Home Products.
    The year was also significant in terms of talent acquisition and employee
productivity.  Growth in total employees was 23 percent, while sales per
employee increased 30 percent to $592,000 in 2000, compared to $457,000 in
1999.  Depth was added in both the ENBREL and Specialty Therapeutics
franchises, as well as early-stage research in vascular biology, oncology and
protein engineering.  With a retention rate of 95%, and selection by FORTUNE
magazine as one of the 100 Best Companies to Work for in America, the company
is well positioned to continue to attract and retain talent.
    Immunex Corporation is a leading biopharmaceutical company dedicated to
improving lives through immune system science innovations.
    American Home Products is one of the world's largest research-based
pharmaceutical and health care products companies.  It is a leader in the
discovery, development, manufacturing and marketing of prescription drugs,
including biotechnological and vaccine products, animal health care products
and over-the-counter medications.
    NOTE:  This new release contains forward-looking statements that involve
risks and uncertainties, including risks associated with clinical development,
regulatory approvals, our reliance on third-party manufacturers, product
commercialization and other risks described from time to time in the SEC
reports filed by Immunex, including the most recently filed Form 10-Q.  An
electronic version of this news release -- as well as additional information
about Immunex of interest to investors, customers, future employees and
patients -- is available on the Immunex home page at http://www.immunex.com.


                               IMMUNEX CORPORATION
                        CONSOLIDATED STATEMENTS OF INCOME
                     (in thousands except per share amounts)

                                   Three months ended    Twelve months ended
                                       December 31,           December 31,
                                    2000        1999        2000       1999

    Revenues:
      Product sales              $248,776    $158,750    $828,828   $519,287
      Royalty and contract
       revenue                      1,892       3,895      33,001     22,431
                                  250,668     162,645     861,829    541,718
    Operating expenses:
      Cost of product sales        72,972      50,271     243,144    159,269
      Research and development     46,647      37,139     166,712    126,682
      Selling, general
       and administrative         101,324      62,568     344,383    216,714
                                  220,943     149,978     754,239    502,665
    Operating income               29,725      12,667     107,590     39,053
    Other income (expense):
      Interest income              19,865      10,108      56,816     26,150
      Interest expense              (873)     (3,479)    (10,737)    (8,656)
      Other income, net             1,570          50       2,979        277
                                   20,562       6,679      49,058     17,771
    Income before income taxes     50,287      19,346     156,648     56,824
    Provision for income taxes      1,131       3,130       2,296     12,500
    Net income                    $49,156     $16,216    $154,352    $44,324

    Net income per common
     share, diluted                 $0.09       $0.03      $ 0.28     $ 0.08

    Number of shares used for
     per share amounts            565,273     534,648     549,250    529,974


                               IMMUNEX CORPORATION
                      CONDENSED CONSOLIDATED BALANCE SHEETS
                                  (in thousands)

                                                December 31,    December 31,
                                                      2000            1999
    Assets:
      Current assets                              $1,756,281       $791,181
      Property, plant and equipment, net             174,049        110,445
      Other assets                                   109,043         39,615
    Total assets                                  $2,039,373       $941,241
    Liabilities and shareholders' equity:
      Current liabilities                           $200,441       $135,085
      Long-term debt and other obligations               796        450,826
      Shareholders' equity                         1,838,136        355,330
    Total liabilities and shareholders' equity    $2,039,373       $941,241


                               IMMUNEX CORPORATION
                 CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
                                  (in thousands)

                                                      Twelve months ended
                                                           December 31,
                                                       2000           1999

    Cash flows from operating activities:
      Net income                                    $154,352        $44,324
      Depreciation and amortization                   21,781         20,081
      Deferred income tax provision                       --         12,050
      Change in working capital and other            (4,253)         36,277
        Net cash provided by operating activities    171,880        112,732

    Cash flows from investing and
     financing activities:
      Purchases of property, plant and equipment    (80,675)       (35,563)
      Purchase of property held for development     (27,509)             --
      Net purchases of investments                 (612,938)      (352,207)
      Net proceeds from common stock offering        771,207             --
      Proceeds from issuance of convertible note to
       AHP, net                                           --        449,000
      Other investing and financing activities        70,032         43,208
        Net cash provided by investing
         and financing activities
         financing activities                        120,117        104,438
    Net increase in cash and cash equivalents       $291,997       $217,170


SOURCE Immunex Corporation




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