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Cambrex Reports Fourth Quarter and Full Year 2005 Results

    EAST RUTHERFORD, N.J., Feb. 22 /PRNewswire-FirstCall/ -- Cambrex
Corporation (NYSE: CBM) reports fourth quarter and full year 2005 results for
the period ended December 31, 2005.
    (Logo:  http://www.newscom.com/cgi-bin/prnh/20000613/CAMBREXLOGO )

    Fourth Quarter 2005 Consolidated Results
    For the fourth quarter 2005, the Company reported a net loss of $140.3
million, or $5.26 per diluted share, compared to net income of $4.9 million,
or $0.18 per diluted share, in the fourth quarter 2004.  Fourth quarter 2005
results include charges of $5.40 per diluted share from the following items:

     * An $87.2 million ($3.27 per diluted share) goodwill impairment and a
       $35.8 million ($1.34 per diluted share) charge to reduce the carrying
       value of long-lived assets recorded in Operating Expenses.  The
       long-lived asset impairment includes a tax benefit of $2.3 million.
       The goodwill and asset impairments were recorded as the result of lower
       long-term profitability projections for the Biopharma segment and two
       small European reporting units in the Human Health segment.

     * A $16.9 million ($0.63 per diluted share) valuation allowance recorded
       within the Income Tax Provision to write down the carrying value of
       certain US tax assets that had previously been preserved by tax
       strategies.  The valuation allowance results from the Company's recent
       history of domestic losses and its short-term projections for continued
       domestic losses.

     * A $4.2 million ($0.16 per diluted share) charge recorded within
       Administrative Expense primarily due to the severance agreement with
       the Company's former CEO.

    Excluding the charges noted above, fourth quarter 2005 net earnings were
$3.8 million ($0.14 per diluted share).  Please see the pro forma-to-GAAP
reconciliation at the end of this press release.  Management believes that pro
forma results provide a more meaningful representation of the Company's
operating results for the periods presented due to the magnitude and nature of
the charges recorded in the fourth quarter 2005, full year 2005 and full year
2004.
    Sales increased 3.0% to $120.9 million in the fourth quarter 2005,
including a 5.1% unfavorable impact from foreign currency, from $117.4 million
in the fourth quarter 2004 resulting from improved sales performance in the
Biopharma and Bioproducts segments.
    Fourth quarter 2005 gross margins decreased to 33.9% from 37.5% in the
fourth quarter 2004 primarily due to lower Bioproducts margins resulting
primarily from increased headcount to support current and future activity
levels, lower Biopharma margins caused by higher fixed plant costs and adverse
product mix and lower Human Health margins due to unfavorable absorption and
lower pricing.  Foreign currency favorably impacted consolidated gross margin
by 0.4 percentage points in the fourth quarter 2005.

    Full Year 2005 Consolidated Results
    Full year 2005 sales increased 2.9% to $452.0 million, including a 0.4%
unfavorable impact resulting from foreign currency, from $439.1 million in
2004 due to higher sales in the Bioproducts and Human Health segments
partially offset by lower sales in the Biopharma segment.
    Full year 2005 gross margins decreased to 35.7% from 38.9% in 2004 due to
lower Bioproducts margins resulting from increased headcount to support
current and future activity levels, lower Biopharma margins caused by higher
fixed plant costs and adverse product mix and lower Human Health margins due
to unfavorable absorption and lower pricing.  Foreign currency unfavorably
impacted gross margin by 0.1 percentage point in 2005.
    For the full year 2005, the Company reported a net loss of $129.2 million,
or $4.88 per diluted share, compared to a net loss of $26.9 million, or $1.03
per diluted share, in 2004.  In addition to the charges recorded in the fourth
quarter 2005 discussed above, earlier in 2005 the Company recorded a tax
benefit of $3.3 million ($0.13 per diluted share) due to a favorable Swedish
court decision and a charge of $1.3 million ($0.05 per diluted share) for the
expected cost of environmental remediation of a former site.  Excluding the
charges noted above, 2005 net earnings were $12.9 million ($0.48 per diluted
share).
    In 2004, a $48.7 million ($1.84 per diluted share) goodwill impairment was
recorded in Biopharma Operating Expense, $2.9 million of income was recorded
in Bioproducts Operating Expense due to the early termination of a customer
contract and a $1.0 million charge was recorded in Human Health Operating
Expense due to the reorganization and related workforce reductions at a
European facility.  Excluding the charges noted above, 2004 net earnings were
$20.0 million ($0.76 per diluted share).
    The total number of contract development and manufacturing projects
processed by the Company's Biopharma, Cell Therapy (within the Bioproducts
segment) and Human Health businesses increased 61% in full year 2005 compared
to full year 2004.  Compared to the third quarter 2005, two Human Health
projects moved from pre-registration to approved status and two Biopharma
projects ended due to unfavorable regulatory developments at two customers.


                               Number of projects
                             Full year        Full year
    Project type               2004             2005            %Change
    Biopharma                    15               23               53%
    Cell Therapy                  8               17              113%
    Human Health*                39               60               54%

     * Note: The Human Health line does not include projects for approved
             therapeutics.

    Bioproducts
    The Bioproducts segment includes products and services for research and
therapeutic applications.  Bioproducts sales in the fourth quarter 2005
increased 5.7% to $35.9 million, including a 3.7% unfavorable impact from
foreign currency, from $33.9 million in the fourth quarter 2004 primarily due
to higher sales volumes of research products, cell therapy and related
services and therapeutic media.
    Fourth quarter 2005 Bioproducts gross margin decreased to 50.1% from 56.8%
in the fourth quarter 2004 primarily due to increased headcount to support
current and future activity levels, higher utilities and foreign currency
effects partially offset by favorable absorption from higher sales volumes.
Foreign currency unfavorably impacted Bioproducts gross margin by 1.1
percentage point in the fourth quarter 2005.
    Fourth quarter 2005 Bioproducts operating profit margin increased to 14.7%
from 13.3% in the fourth quarter 2004 primarily due to lower commissions and
bonus accruals.  Foreign currency unfavorably impacted Bioproducts operating
profit margin by 1.0 percentage point in the fourth quarter 2005.

    Biopharma
    The Biopharma segment consists of the Company's contract biopharmaceutical
process development and manufacturing business.  Sales in the fourth quarter
2005 increased 21.0% to $14.0 million from $11.5 million in the fourth quarter
2004 due to higher suite revenues resulting from the timing of client projects
and higher material reimbursement revenue partially offset by lower process
development revenues.
    Fourth quarter 2005 Biopharma gross margin decreased to 7.1% versus 13.7%
in the fourth quarter 2004 driven by higher material reimbursements which
contribute virtually no gross profit, higher utility costs, costs associated
with pre-approval inspections (PAIs) and the depreciation of the 2800 liter
bioreactor that was commissioned earlier in 2005.
    The fourth quarter 2005 Biopharma operating loss was $90.5 million versus
an operating loss of $0.7 million in the fourth quarter 2004.  The fourth
quarter 2005 operating loss resulted principally from a $76.8 million goodwill
impairment and an $11.4 million charge to reduce the carrying value of long-
lived assets.  Excluding the charges noted above, Biopharma had an operating
loss of $2.3 million in the fourth quarter 2005 versus $0.7 million in the
fourth quarter 2004 due to lower gross profit and a $0.7 million charge
related to an investment made for a large pharmaceutical client whose project
was cancelled due to an unfavorable regulatory development.  Foreign currency
had no impact on Biopharma sales, gross margin or operating profit margin.

    Human Health
    The Human Health segment consists of small molecule active pharmaceutical
ingredients (APIs), advanced intermediates and other products derived from
organic chemistry.  Human Health sales in the fourth quarter 2005 decreased
1.2% to $71.0 million, including a 6.6% unfavorable impact due to foreign
currency, from $71.9 million in the fourth quarter 2004.  Higher net sales
volumes were more than offset by the unfavorable impact of foreign currency.
    Fourth quarter 2005 Human Health gross margin decreased to 31.0% from
32.3% in the fourth quarter 2004 primarily due to higher inventory reserves,
lower pricing and higher production costs partially offset by favorable
product mix and higher sales volumes.  Foreign currency favorably impacted
gross margin by 1.2 percentage points in the fourth quarter 2005.
    The fourth quarter 2005 Human Health operating loss was $26.0 million
versus operating profit of $13.1 million in the fourth quarter 2004.  The
fourth quarter 2005 operating loss resulted from a $26.7 million charge to
reduce the carrying value of long-lived assets and a $10.4 million goodwill
impairment. Excluding the charges noted above, Human Health operating margins
were 15.7% in the fourth quarter 2005 compared to 18.3% in the fourth quarter
2004 due to lower gross margins and higher bonus accruals.  Foreign currency
favorably impacted Human Health operating margin by 1.4 percentage points in
the fourth quarter 2005.

    Fourth Quarter and Full Year 2005 Consolidated Operating, Interest and Tax
Expenses
    Sales and marketing expense in the fourth quarter 2005 decreased to $8.8
million, or 7.3% of sales, from $9.2 million, or 7.8% of sales in the fourth
quarter 2004, principally due to the impact of foreign currency.  Sales and
marketing expense for the full year 2005 increased to $34.0 million, or 7.5%
of sales, from $32.6 million, or 7.4%, in 2004 primarily due to the cost of
additional headcount in Europe to support the Bioproducts business.
    Fourth quarter 2005 Research and Development Expense was flat with prior
year at $5.7 million.  Research and Development Expense for the full year 2005
increased to $22.3 million, or 4.9% of sales, from $19.7 million, or 4.5% of
sales, in 2004 due to increased spending for rapid microbial detection and
FlashGel(TM) product development and due to growth in the Human Health custom
development area.
    Fourth quarter 2005 Administrative Expense increased to $20.6 million, or
17.0% of sales, from $17.4 million, or 14.7% of sales, in the fourth quarter
2004 due to a $4.2 million charge comprised primarily of the cost of the
severance agreement with the Company's former CEO.  Excluding the $4.2 million
charge, Administrative Expense in the fourth quarter 2005 declined $1.0
million compared to the fourth quarter 2004 primarily due to lower corporate
expenses and the impact of foreign currency.   Excluding the charges recorded
in 2005, full year 2005 Administrative Expense decreased to $65.8 million, or
14.6% of sales, from $70.1 million, or 16.0% of sales, principally due to
lower SARS expense and legal and professional fees partially offset by
increased headcount and higher environmental expenses.
    The Company completed its annual analysis of the carrying value of
goodwill and long-lived assets and has recorded a $125.3 million charge in the
fourth quarter 2005 comprised of an $87.2 million goodwill impairment and a
$38.1 million pre-tax impairment of long-lived assets resulting from lower
projections of long-term profitability for the Biopharma segment and two small
European reporting units within the Human Health segment.  The impairment
writes down all the remaining goodwill and a portion of the long-lived assets
at the respective sites.  The impairment within the Biopharma segment partly
resulted from unfavorable regulatory developments at a large client in the
fourth quarter 2005.
    Net Interest Expense in the fourth quarter and full year 2005 is
essentially flat with prior year at $2.5 million and $10.5 million,
respectively.  The average interest rate in the fourth quarter 2005 and 2004
is 5.6% and 5.4% respectively, and for the full year 2005 and 2004 is 5.5%.
    The tax rate in the fourth quarter 2005 was -14.5% compared to 43.6% in
the fourth quarter of 2004.  The fourth quarter 2005 tax rate includes the
impact of the goodwill and long-lived asset impairments discussed above and a
$16.9 million valuation allowance to write down the carrying value of certain
US tax assets that had been previously preserved by tax strategies.  These
charges increased fourth quarter 2005 Tax Expense by $14.6 million.  Excluding
the charges recorded in the fourth quarter 2005, the effective tax rate is
45.8% in the fourth quarter 2005 versus 43.6% in the fourth quarter 2004 due
to the geographic distribution of income or losses.  Since the Company is
currently not recording any tax benefit for US and certain European losses,
the consolidated effective tax rate is expected to be highly volatile.
    The full year tax rate in 2005 was -23.3% compared to -126.5% in 2004.
The 2005 results include the impact of the items affecting the fourth quarter
2005, as discussed above, and a $3.3 million positive impact on tax expenses
related to the previously discussed Swedish tax court decision.  Excluding the
charges recorded in 2005 and 2004, the 2005 consolidated effective tax rate
increased to 50.5% from 40.8% in 2004.
    Capital expenditures and depreciation for the fourth quarter 2005 were
$12.3 million and $9.0 million compared to $11.7 million and $9.5 million in
the fourth quarter 2004, respectively.  Capital expenditures and depreciation
for 2005 are $40.3 million and $36.6 million compared to $39.5 million and
$38.9 million in 2004, respectively.

    Guidance
    The Company is providing full year 2006 guidance for sales growth to be
within the range of 4% to 8% and net earnings to be in the range of $0.75 to
$0.95 per fully diluted share.
    For the year 2006, guidance for capital expenditures, depreciation and
amortization for continuing operations is currently expected to be
approximately $40-$45 million, $36 million, and $2.0 million, respectively.
The Company expects the full year 2006 effective tax rate to be approximately
40-45%.  The full year and quarterly effective tax rates will continue to be
highly sensitive to the geographic mix of income or losses.
    The above guidance excludes any costs associated with the previously
announced agreement to purchase Cutanogen (estimated to be $0.15 per diluted
share depending on the timing of milestone payments), the previously announced
early extinguishment of a portion of the Company's long-term debt ($0.20 per
diluted share) and the previously announced evaluation of strategic
alternatives to enhance shareholder value.
    The financial information contained in this press release is unaudited,
subject to revision and should not be considered final until the 2005 Form
10-K is filed with the US Securities and Exchange Commission.

    Conference Call and Webcast
    The Conference Call to discuss fourth quarter and full year 2005 earnings
will begin at 8:30 a.m. Eastern Time on Thursday, February 23, 2006 and last
approximately 45 minutes.  Those wishing to participate should call
1-888-634-4003 for Domestic, and +1-706-634-6653 for International.  Please
use the conference ID 4188520 and call approximately 10 minutes before the
start time.  The Conference Call will also be webcast in the Investor
Relations section of the Cambrex website located at http://www.cambrex.com.
The webcast will be available for approximately thirty (30) days following the
call.
    A replay of the Conference Call will be available approximately two hours
after the completion of the call through the end of business day, Thursday,
March 2, 2006 by calling 1-800-642-1687 for Domestic, and +1-706-645-9291 for
International.  Please use the conference ID 4188520 too access the replay.

    Forward Looking Statements
    This news release contains "forward-looking statements" within the meaning
of the Private Securities Litigation Reform Act of 1995 and Rule 3b-6 under
The Securities Exchange Act of 1934, including, without limitation, statements
regarding expected performance, especially expectations with respect to sales,
research and development expenditures, earnings per share, capital
expenditures, acquisitions, divestitures, collaborations, or other expansion
opportunities.  These statements may be identified by the fact that words such
as "expects," "anticipates", "intends," "estimates," "believes" or similar
expressions are used in connection with any discussion of future financial and
operating performance.  The forward-looking statements contained herein are
based on current plans and expectations and involve risks and uncertainties
that could cause actual outcomes and results to differ materially from current
expectations including but not limited to, global economic trends,
pharmaceutical outsourcing trends, competitive pricing or product
developments, government legislation and/or regulations (particularly
environmental issues), tax rate, interest rate, technology, manufacturing and
legal issues, changes in foreign exchange rates, performance of minority
investments, uncollectible receivables, loss on disposition of assets,
cancellation or delays in renewal of contracts, and lack of suitable raw
materials or packaging materials, the possibility that the value of the
acquisition of PermaDerm(TM) cultured skin may not be realized or that our
plans to obtain a Humanitarian Device Exemption, completion of clinical trials
and commercialization of PermaDerm cultured skin in the United States may not
be successful and the Company may not receive regulatory approval for its
products.
    For further details and a discussion of these and other risks and
uncertainties, investors are cautioned to review the Cambrex Annual Report on
Form 10-K, including the Forward-Looking Statement section therein, and other
filings with the Securities and Exchange Commission.  The Company undertakes
no obligation to publicly update any forward-looking statement, whether as a
result of new information, future events or otherwise.

    About Cambrex
    Cambrex is a global, diversified life sciences company dedicated to
providing products and services to accelerate and improve the discovery and
commercialization of human therapeutics.  The Company employs approximately
2,000 worldwide.  For more information, please visit http://www.cambrex.com.



                               CAMBREX CORPORATION
                    Statement of Profit and Loss - Pro forma*
                For the Quarters Ended December 31, 2005 and 2004
                                  (in thousands)

                                                 2005              2004
                                                      % of              % of
                                            Amount   Sales    Amount   Sales

    Gross Sales                            $120,853  100.0%  $117,365  100.0%
         Commissions and Allowances            (259)  -0.2%       (20)   0.0%
    Net Sales                               121,112  100.2%   117,385  100.0%

         Other Revenues                         721    0.6%       255    0.2%

    Net Revenue                             121,833  100.8%   117,640  100.2%

         Cost of Sales                       80,850   66.9%    73,571   62.7%

    Gross Profit                             40,983   33.9%    44,069   37.5%

    Operating Expenses
         Sales and Marketing Expense          8,805    7.3%     9,171    7.8%
         Research and Development Expense     5,730    4.7%     5,723    4.9%
         Administrative Expense              16,378   13.5%    17,390   14.7%
         Amortization                           564    0.5%       541    0.5%
    Total Operating Expenses                 31,477   26.0%    32,825   27.9%

    Operating Profit                          9,506    7.9%    11,244    9.6%

    Other Expenses
         Interest - Other                     2,533    2.1%     2,479    2.1%
         Other (Income)/Expense, net            (32)   0.0%       134    0.1%
    Total Other Expenses                      2,501    2.1%     2,613    2.2%

    Income Before Taxes                       7,005    5.8%     8,631    7.4%

         Income Tax Provision                 3,208    2.7%     3,760    3.2%

    Net Income                               $3,797    3.1%    $4,871    4.2%

    Basic Earnings per Share
         Net Income                           $0.14             $0.19

    Diluted Earnings per Share
         Net Income                           $0.14             $0.18

    Weighted Average Shares Outstanding
         Basic                               26,654            26,154
         Diluted                             26,683            26,540

    *  Refer to the GAAP to Pro forma Reconciliation.



                               CAMBREX CORPORATION
                       Statement of Profit and Loss - GAAP
                For the Quarters Ended December 31, 2005 and 2004
                                  (in thousands)

                                                2005               2004
                                                     % of               % of
                                          Amount     Sales    Amount   Sales

    Gross Sales                           $120,853   100.0%  $117,365  100.0%
         Commissions and Allowances           (259)   -0.2%       (20)   0.0%
    Net Sales                              121,112   100.2%   117,385  100.0%

         Other Revenues                        721     0.6%       255    0.2%

    Net Revenue                            121,833   100.8%   117,640  100.2%

         Cost of Sales                      80,850    66.9%    73,571   62.7%

    Gross Profit                            40,983    33.9%    44,069   37.5%

    Operating Expenses
         Sales and Marketing Expense         8,805     7.3%     9,171    7.8%
         Research and Development Expense    5,730     4.7%     5,723    4.9%
         Administrative Expense             20,601    17.0%    17,390   14.7%
         Impairment Charges                125,331   103.7%       -      0.0%
         Amortization                          564     0.5%       541    0.5%
    Total Operating Expenses               161,031   133.2%    32,825   27.9%

    Operating (Loss)/Profit               (120,048)  -99.3%    11,244    9.6%

    Other Expenses
         Interest - Other                    2,533     2.1%     2,479    2.1%
         Other (Income)/Expense, net           (32)    0.0%       134    0.1%
    Total Other Expenses                     2,501     2.1%     2,613    2.2%

    (Loss)/Income Before Taxes            (122,549) -101.4%     8,631    7.4%

         Income Tax Provision               17,784    14.7%     3,760    3.2%

    Net (Loss)/Income                    $(140,333) -116.1%    $4,871    4.2%

    Basic Earnings per Share
         Net (Loss)/Income                  $(5.26)             $0.19

    Diluted Earnings per Share
         Net (Loss)/Income                  $(5.26)             $0.18

    Weighted Average Shares Outstanding
         Basic                              26,654             26,154
         Diluted                            26,654             26,540




                             CAMBREX CORPORATION
        Gross Sales, Gross Profit & Operating Profit/(Loss) by Segment
              For the Quarters Ended December 31, 2005 and 2004
                                (in thousands)

                                   Fourth Quarter 2005
                 Gross    Gross    GP%  Operating   OP%   Operating     OP%-
                 Sales    Profit          Profit    GAAP   Profit   Pro forma*
                                         /(Loss)           /(Loss)
                                          -GAAP           -Pro forma*
    Bioproducts  $35,860 $17,956 50.1%    $5,254     14.7%   $5,254     14.7%

    Biopharma    13,951      989  7.1%   (90,517)  -648.8%   (2,316)   -16.6%

    Human Health 71,042   22,038 31.0%   (25,996)   -36.6%   11,134     15.7%

    Corporate         -        -          (8,789)            (4,566)

    Total      $120,853  $40,983 33.9% $(120,048)   -99.3%   $9,506      7.9%


                                   Fourth Quarter 2004
                 Gross    Gross    GP%  Operating   OP%   Operating     OP%-
                 Sales    Profit          Profit    GAAP   Profit   Pro forma*
                                         /(Loss)           /(Loss)
                                          -GAAP           -Pro forma*

    Bioproducts $33,918  $19,254 56.8%    $4,514     13.3%    4,514     13.3%

    Biopharma    11,531    1,577 13.7%      (748)    -6.5%     (748)    -6.5%

    Human Health 71,916   23,238 32.3%    13,149     18.3%   13,149     18.3%

    Corporate         -        -          (5,671)            (5,671)

    Total      $117,365  $44,069 37.5%   $11,244      9.6%   11,244      9.6%


                                                 Gross Sales Comparison

                                              4Q05      4Q04
                                             Gross     Gross    Change Change
                                             Sales     Sales      $       %

    Bioproducts                              $35,860   $33,918  $1,942   5.7%

    Biopharma                                 13,951    11,531   2,420  21.0%

    Human Health                              71,042    71,916    (874) -1.2%

    Total                                   $120,853  $117,365  $3,488   3.0%

    *  Refer to the GAAP to Pro forma Reconciliation.



                               CAMBREX CORPORATION
                    Statement of Profit and Loss - Pro forma*
                  For the Years Ended December 31, 2005 and 2004
                                  (in thousands)

                                                 2005              2004
                                                      % of              % of
                                            Amount   Sales    Amount   Sales

    Gross Sales                            $451,986  100.0%  $439,115  100.0%
         Commissions and Allowances           3,437    0.8%     2,258    0.5%
    Net Sales                               448,549   99.2%   436,857   99.5%

         Other Revenues                       6,548    1.5%     6,800    1.5%

    Net Revenue                             455,097  100.7%   443,657  101.0%

         Cost of Sales                      293,760   65.0%   272,917   62.1%

    Gross Profit                            161,337   35.7%   170,740   38.9%

    Operating Expenses
         Sales and Marketing Expense         34,038    7.5%    32,584    7.4%
         Research and Development Expense    22,331    4.9%    19,659    4.5%
         Administrative Expense              65,767   14.6%    70,127   16.0%
         Amortization                         2,282    0.5%     1,921    0.4%
    Total Operating Expenses                124,418   27.5%   124,291   28.3%

    Operating Income                         36,919    8.2%    46,449   10.6%

    Other Expenses
         Interest - Other                    10,815    2.4%    10,950    2.5%
         Other Expenses                          40    0.0%        73    0.0%
    Total Other Expenses                     10,855    2.4%    11,023    2.5%

    Income Before Taxes                      26,064    5.8%    35,426    8.1%

         Provision for Income Taxes          13,174    2.9%    14,461    3.3%

    Income From Continuing Operations       $12,890    2.9%   $20,965    4.8%

    Discontinued Operations

    Loss From Discontinued Operations             -              (978)

    Net Income                              $12,890           $19,987

    Basic Earnings per Share
         Income From Continuing Operations    $0.49             $0.80
         Loss From Discontinued Operations     $  -            $(0.03)
         Net Income                           $0.49             $0.77

    Diluted Earnings per Share
         Income From Continuing Operations    $0.48             $0.79
         Loss From Discontinued Operations     $  -            $(0.03)
         Net Income                           $0.48             $0.76

    Weighted Average Shares Outstanding
         Basic                               26,456            26,094
         Diluted                             26,581            26,462

    *  Refer to the GAAP to Pro forma Reconciliation.



                               CAMBREX CORPORATION
                       Statement of Profit and Loss - GAAP
                  For the Years Ended December 31, 2005 and 2004
                                  (in thousands)

                                                2005               2004
                                                      % of              % of
                                           Amount    Sales    Amount   Sales

    Gross Sales                            $451,986  100.0%  $439,115  100.0%
         Commissions and Allowances           3,437    0.8%     2,258    0.5%
    Net Sales                               448,549   99.2%   436,857   99.5%

         Other Revenues                       6,548    1.5%     6,800    1.5%

    Net Revenue                             455,097  100.7%   443,657  101.0%

         Cost of Sales                      293,760   65.0%   272,917   62.1%

    Gross Profit                            161,337   35.7%   170,740   38.9%

    Operating Expenses
         Sales and Marketing Expense         34,038    7.5%    32,584    7.4%
         Research and Development Expense    22,331    4.9%    19,659    4.5%
         Administrative Expense              71,290   15.9%    70,127   16.0%
         Impairment Charges                 125,331   27.7%    48,720   11.1%
         Other, net                               -    0.0%    (1,863)  -0.4%
         Amortization                         2,282    0.5%     1,921    0.4%
    Total Operating Expenses                255,272   56.5%   171,148   39.0%

    Operating Loss                          (93,935) -20.8%      (408)  -0.1%

    Other Expenses
         Interest - Other                    10,815    2.4%    10,950    2.5%
         Other Expenses                          40    0.0%        73    0.0%
    Total Other Expenses                     10,855    2.4%    11,023    2.5%

    Loss Before Taxes                      (104,790) -23.2%   (11,431)  -2.6%

         Provision for Income Taxes          24,421    5.4%    14,461    3.3%

    Loss From Continuing Operations       $(129,211) -28.6%  $(25,892)  -5.9%

    Discontinued Operations

    Loss  From Discontinued Operations            -              (978)

    Net Loss                              $(129,211)         $(26,870)

    Basic Earnings per Share
         Loss From Continuing Operations     $(4.88)           $(0.99)
         Loss From Discontinued
          Operations                           $  -            $(0.04)
         Net Loss                            $(4.88)           $(1.03)

    Diluted Earnings per Share
         Loss From Continuing Operations     $(4.88)           $(0.99)
         Loss From Discontinued
          Operations                           $  -            $(0.04)
         Net Loss                            $(4.88)           $(1.03)

    Weighted Average Shares Outstanding
         Basic                               26,456            26,094
         Diluted                             26,456            26,094



                             CAMBREX CORPORATION
        Gross Sales, Gross Profit & Operating Profit/(Loss) by Segment
                For the Years Ended December 31, 2005 and 2004
                                (in thousands)

                                       Full Year 2005
                 Gross    Gross    GP%  Operating   OP%   Operating     OP%-
                 Sales    Profit          Profit    GAAP   Profit   Pro forma*
                                         /(Loss)           /(Loss)
                                          -GAAP           -Pro forma*

    Bioproducts $149,498  $77,908  52.1%  $25,753    17.2%    25,753    17.2%

    Biopharma     41,698   (3,811) -9.1% (103,062) -247.2%   (14,861)  -35.6%

    Human Health 260,790   87,240  33.5%    8,377     3.2%    45,507    17.4%

    Corporate          -        -         (25,003)           (19,480)

    Total       $451,986 $161,337  35.7% $(93,935)  -20.8%    36,919     8.2%


                                       Full Year 2004
                 Gross    Gross    GP%  Operating   OP%   Operating     OP%-
                 Sales    Profit          Profit    GAAP   Profit   Pro forma*
                                         /(Loss)           /(Loss)
                                          -GAAP           -Pro forma*

    Bioproducts $136,108  $74,930  55.1%  $26,386    19.4%    23,523    17.3%

    Biopharma     43,270    4,880  11.3%  (53,813) -124.4%    (5,093)  -11.8%

    Human Health 259,737   90,930  35.0%   50,651    19.5%    51,651    19.9%

    Corporate          -        -         (23,632)            (23,632)

    Total       $439,115 $170,740  38.9%    $(408)   -0.1%     46,449   10.6%


                                                 Gross Sales Comparison

                                             2005      2004
                                            Gross     Gross    Change  Change
                                            Sales     Sales       $       %

    Bioproducts                            $149,498  $136,108  $13,390   9.8%

    Biopharma                                41,698    43,270   (1,572) -3.6%

    Human Health                            260,790   259,737    1,053   0.4%

    Total                                  $451,986  $439,115  $12,871   2.9%

    *  Refer to the GAAP to Pro forma Reconciliation.



                             CAMBREX CORPORATION
             GAAP to Pro forma Reconciliation - Net (Loss)/Income
         For the Quarters and Years ended December 31, 2005 and 2004

                                          Fourth Quarter     Fourth Quarter
                                                2005               2004
                                        Net (Loss)/  Diluted   Net    Diluted
                                          Income       EPS    Income     EPS

    Net (Loss)/Income - As Reported     $(140,333)   $(5.26)   $4,871   $0.18

    Impairment - Goodwill and Long Lived
     Assets (net of tax)                  122,981      4.61         -       -

    Executive Severance                     4,223      0.16         -       -

    Domestic Tax Valuation Allowance       16,926      0.63         -       -

    Net Income - Pro forma                 $3,797     $0.14    $4,871   $0.18


                                              Full Year          Full Year
                                                 2005               2004
                                           Net                Net
                                          (Loss)/ Diluted    (Loss)/  Diluted
                                          Income      EPS     Income     EPS

    Net Loss - As Reported              $(129,211)  $(4.88)  $(26,870) $(1.03)

    Impairment - Goodwill and Long Lived
     Assets (net of tax)                  122,981     4.63     48,720    1.84

    Executive Severance                     4,223     0.16          -       -

    Domestic Tax Valuation Allowance       16,926     0.64          -       -

    Tax Benefit (Swedish Tax Item)         (3,329)   (0.13)         -       -

    Environmental Reserve                   1,300     0.05          -       -

    Early Termination of Bioproducts
     Customer Contract                          -        -     (2,863)  (0.11)

    Restructuring at European Site              -        -      1,000    0.04

    Net Income - Pro forma                $12,890    $0.48    $19,987   $0.76


                             CAMBREX CORPORATION
    GAAP to Pro forma Reconciliation - Operating Profit/(Loss) by Segment
         For the Quarters and Years ended December 31, 2005 and 2004

                                         Fourth Quarter 2005
                                                  Human
                          Bioproducts  Biopharma  Health   Corporate   Total

    Operating Profit/(Loss)
     - As Reported          $5,254     $(90,517) $(25,996) $(8,789) $(120,048)

    Impairment Charge            -       88,201    37,130        -    125,331

    Executive Severance          -            -         -     4,223     4,223

    Operating Profit/(Loss)
     - Pro forma            $5,254      $(2,316)  $11,134   $(4,566)   $9,506


                                         Fourth Quarter 2004
                                                  Human
                          Bioproducts  Biopharma  Health   Corporate   Total

    Operating Profit/(Loss)
     - As Reported          $4,514        $(748)  $13,149   $(5,671)  $11,244

    Operating Profit/(Loss)
     - Pro forma            $4,514        $(748)  $13,149   $(5,671)  $11,244


                                            Full Year 2005
                                                  Human
                          Bioproducts  Biopharma  Health   Corporate   Total

    Operating Profit/(Loss)
     - As Reported         $25,753    $(103,062)   $8,377  $(25,003) $(93,935)

    Impairment Charge            -       88,201    37,130         -   125,331

    Executive Severance          -            -         -     4,223     4,223

    Environmental Reserve        -            -         -     1,300     1,300

    Operating Profit/(Loss)
     - Pro forma           $25,753     $(14,861)  $45,507  $(19,480)  $36,919


                                               Full Year 2004
                                                  Human
                          Bioproducts  Biopharma  Health   Corporate   Total

    Operating Profit/(Loss)
     - As Reported         $26,386     $(53,813)  $50,651  $(23,632)    $(408)

    Impairment Charge            -       48,720         -         -    48,720

    Early Termination of
     Bioproducts Customer
     Contract               (2,863)           -         -         -    (2,863)

    Restructuring                -            -     1,000         -     1,000

    Operating Profit/(Loss)
     - Pro forma           $23,523      $(5,093)  $51,651  $(23,632)  $46,449



                               CAMBREX CORPORATION
                           Consolidated Balance Sheet
                        As of December 31, 2005 and 2004
                                 (in thousands)

    Assets                                            2005              2004

    Cash and Cash Equivalents                      $45,932           $91,532
    Trade Receivables, net                          74,425            68,370
    Inventories, net                                93,617            91,039
    Deferred Tax Asset                               1,162             2,605
    Other Current Assets                            17,652            20,825
      Total Current Assets                         232,788           274,371

    Property, Plant and Equipment, Net             222,130           280,790
    Goodwill and Other Intangibles                 135,897           230,656
    Other Non-Current Assets                         5,985             6,168

      Total Assets                                $596,800          $791,985

    Liabilities and Stockholders' Equity

    Trade Accounts Payable                         $38,813           $38,552
    Accrued Liabilities                             51,819            52,181
    Short-term Debt and Current Portion
     of Long-term Debt                               1,514             1,400
      Total Current Liabilities                     92,146            92,133

    Long-term Debt                                 186,819           226,187
    Deferred Tax Liabilities                        31,135            21,686
    Other Non-Current Liabilities                   61,314            60,663

      Total Liabilities                           $371,414          $400,669

      Stockholders' Equity                        $225,386          $391,316

      Total Liabilities and Stockholders'
       Equity                                     $596,800          $791,985



SOURCE Cambrex Corporation




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    CONTACT:
    Luke M. Beshar, Executive Vice President &
    CFO, +1-201-804-3010, luke.beshar@cambrex.com, or Anne-Marie
    Hess, Senior Director, Investor Relations, +1-201-804-3062,
    annemarie.hess@cambrex.com, both of Cambrex Corporation