Information Rich Detection systems, consumables, data systems, and vacuum
components shown for first time at trade show
NEW ORLEANS, March 3 /PRNewswire-FirstCall/ -- New information rich
detection systems and laboratory consumables showcase Varian, Inc. (Nasdaq:
VARI) technologies for solving important life science and chemical analysis
challenges at the 2008 Pittsburgh Conference on Analytical Chemistry and
Applied Spectroscopy (PITTCON). Booth # 4621
At PITTCON 2008, Varian, Inc. highlights the following products:
920-LC
The Varian 920-LC is a fully automated, computer controlled analytical
HPLC (High Performance Liquid Chromatography) system that offers "Fast LC"
capabilities, state of the art performance, improved productivity, high
sensitivity detectors and a fully automated validation package for
customers who operate in a regulated environment. The system is
preconfigured, pre-plumbed and pre-tested before shipment, significantly
reducing the time required to achieve maximum sample throughput. A choice
of built-in, programmable dual-wavelength or information-rich Diode Array
(190-900 nm) UV-Vis detectors feature low noise and high sensitivity to
deliver lower detection limits for trace analysis. Optional fluorescence,
refractive index, and evaporative light scattering detectors allow a wide
variety of analyses to be performed with the 920-LC.
940-LC
The 940-LC is a dedicated analytical to semi-preparative (semi-prep)
system. It can be used both as an analytical HPLC and for scaling-up flows
to work with larger capacity preparative scale columns.
The Varian 940-LC saves time and valuable sample material by allowing
chromatographers to optimize their separations and collect purified
components on the same instrument. Delivering flow rates of 0.025 ml/min up
to 200 ml/min, the 940-LC is suitable for use with both 4.6 mm ID
analytical columns and, following a linear scale-up, 2" semi-preparative
columns. Users can maintain the separation and resolution of the smaller
column while significantly increasing the mass of purified material.
Fast LC Columns
Pursuit(R) XRs Ultra 2.8 and Pursuit UPS 2.4 columns allow
chromatographers to achieve "Fast LC" with HPLC and LC/MS systems at a
fraction of the cost of ultra-high pressure systems. Pursuit XRs Ultra 2.8
provides enhanced speed for virtually any HPLC instrument. Optimized 2.8
micron silica particles allow chemists to increase flow rates and use a
wide range of mobile phases without going above the maximum operating
pressure of the instrument. At the same time, it delivers better resolution
(10-15% higher efficiency) than typical 3 micron columns. Users can get
high speed performance from conventional LC systems, avoiding the need to
invest in new equipment. Pursuit UPS 2.4 columns are designed to provide
improved performance on standard 'low dead-volume' HPLC systems without the
need for ultra-high pressures. With approximately 50% lower back pressure
than sub-2 micron columns, and near equal efficiencies, Pursuit UPS 2.4
delivers better resolution and increased sensitivity at moderate flows and
back pressures.
TOP-RNA(TM) and TOP-DNA(TM)
Two new TOP (Trityl-on Oligonucleotide Purification) products are
available for the purification of synthetic oligonucleotides (oligos):
TOP-DNA and TOP-RNA. Both TOP products allow full length oligos to bind to
the sorbent bed while salts, incomplete oligos and other impurities are
washed away. Subsequent cleavage of the protective dimethoxytrityl
("trityl") groups releases the purified completed product. Purification and
de-tritylation within the TOP cartridge results in higher yields and
greater purity of synthesized product in less time than with alternative
methods. TOP-DNA is designed to purify both short and long DNA oligos using
a common method. TOP-RNA is a complete solution that includes cartridges
and proprietary buffers specifically for RNA oligos.
VF-WAXms(TM)
The VF-WAXms capillary gas chromatography (GC) column is designed for
applications in the food, flavor and fragrance industries, especially where
trace analysis is required. VF-WAXms is the first wax column designed to
provide high performance GC with all analytical detectors, including MS
detectors. VF-WAXms accomplishes this by virtue of its highly inert
stationary phase that minimizes column breakdown, or bleed. Bleeding
contaminates detectors, reducing productivity, increasing downtime and
costs, and increasing background noise in the chromatography system. The
background noise can also mask the presence of very low levels of
compounds. Therefore, the ultra-low bleed characteristics are particularly
important as statutory methods increasingly demand lower detection limits.
VF-WAXms has the lowest bleed of any wax column available, offering a
marked advantage over conventional wax columns in the determination of
trace constituents.
Plexa(TM) PCX
The new Plexa PCX is designed specifically to provide a single, simple
solid phase extraction (SPE) method for basic compounds. It is ideal for
applications in pharmacokinetics, pharmacodynamics, forensics, toxicology,
food safety and environmental investigation. Plexa PCX uses a polymer
cation exchange mechanism that combines the outstanding properties of
Varian's Bond Elut(R) Plexa -- superior flow characteristics and improved
analytical performance -- with strong cation exchange capability. This
advanced SPE sorbent effectively removes neutral and acidic interferences
from the sample matrix and concentrates basic analytes, resulting in
improved sensitivity, quantification and analytical performance. Both Bond
Elut Plexa and Plexa PCX reduce ion suppression. The unique polymer design
excludes proteins and avoids strong binding of phospholipids, so efficient
removal of these interferences from biological samples is ensured.
IDP-3 Dry Scroll Pump
The innovative IDP-3 brings the proven benefits of dry scroll
technology to applications where vacuum performance, pump size and
environmental concerns are critical. Its small size, low noise and low
power demand allow easy integration into OEM systems. This pump provides
affordable oil-free vacuum for a wide variety of applications from
analytical instrumentation and high energy physics to semiconductor
fabrication and industrial processing. The IDP-3 allows full isolation of
all pumped gases and the scroll pump design minimizes the possibility of
catastrophic failures such as seizing or sudden vacuum loss inherent to
rotary vane or diaphragm pumps. The IDP-3 measures 14 x 7 x 6 inches (356 x
178 x 152 mm), yet delivers a robust pumping speed of 60 L/m and a very low
base pressure of less than 250 mTorr -- almost four times lower than an
equivalently sized membrane/diaphragm pump. The oil free design not only
negates the possibility of oil contamination in the vacuum system, but it
reduces the total cost of ownership by completely eliminating the cost of
oil and related maintenance costs for its filling, disposal, and cleanup.
300-MS GC/MS
The 300-MS is designed to enhance productivity in high-throughput,
routine laboratories and is available as a triple-quadrupole MS or a
single-quadrupole MS that can later be upgraded to a triple-quadrupole. It
is capable of screening or quantifying more than 150 compounds in a single
sample run. A choice of sample introduction and ionization methods
addresses the complete range of sample types encountered in routine GC/MS
laboratory. Both CI (chemical ionization) and EI (electron ionization) are
available for sensitive detection and structural confirmation. The 300-MS
is controlled by MS Workstation which automatically handles quantitation
and data review for the large volume of samples and compounds analyzed in a
high-throughput laboratory. In a addition to the 300-MS, Varian offers a
complete GC/MS solution to its customers, including: a choice of
autosamplers, Varian's MS Workstation (v6.9) software, industry standard
gas chromatographs, and a comprehensive line of chromatography columns
including FactorFour(R) low bleed GC columns.
400-DS
The 400-DS dissolution system is designed to simplify the testing of
drug formulations with extremely low quantities of active ingredients. It
meets the compendial requirements of a USP Apparatus 7 and supports the
testing of combinatorial products in which small amounts of drug are
combined as part of a medical device such as a stent or implant. The
instrument was designed to minimize evaporation, resulting in greater
accuracy of test results (less than 0.2% volume loss per 24 hours, even
when used with aqueous-organic solutions.) The closed-cell design of the
400-DS features a patent-pending magnetic reciprocation mechanism for
mixing. Media replacement and sampling capabilities are built into the
instrument. The 400-DS can run up to 13 samples at one time and is
available in both 5 and 10 mL versions, significantly smaller media volumes
than is common with traditional dissolution apparatus. The 400-DS is
controlled by a PC using Varian software that provides compliance with 21
CFR Part 11 requirements for pharmaceutical laboratories. The software
simplifies method management, system configuration, data security, record
retention and audit features. A single PC can independently control up to
four 400-DS units.
Flash Chromatography
Analogix' leading flash chromatography technology is now a part of
Varian, Inc. The IntelliFlash 310(TM) purification instrument increases
productivity for medicinal chemists through its "Ready to Run" technology
which assures the system's readiness and guides user setup. Exclusive
multiple UV wavelength collection and detection technology effectively
eliminate sample impurities. Advanced rack management with RFID technology,
fraction collector feedback systems and run finalization minimize
previously uncontrolled sources of sample loss. When used in combination
with SuperFlash purification columns, the Intelliflash 310 reliably
delivers separations with high quality peak shapes that maximize compound
recovery. A large selection of column sizes provides users with
cost-effective choices. Advanced sorbent options handle the most demanding
compound purifications.
PL aquagel-OH(TM)
Polymer Laboratories, a part of Varian, Inc. (Booth #4521) has expanded
its PL aquagel-OH range of columns for aqueous size exclusion
chromatography (SEC) by releasing the new PL aquagel-OH 10 (8 micron)
column for the analysis of oligomers and low molecular weight polymers. The
popular 8 micron particle size offers high resolution yet ensures that back
pressures remain low during analysis. The addition of the PL aquagel-OH 10
8 micron column completes the PL aquagel-OH range, allowing chemists to
undertake the comprehensive analysis of all water soluble polymers, from
high molecular weight synthetic polymers and biomolecules down to very low
molecular weight oligomers.
PolarGel-L
The PolarGel-L gel permeation chromatography (GPC) column, also from
Varian Polymer Laboratories, extends the successful PolarGel(TM) range of
columns for the analysis of polymers soluble in polar solvents.
Complementary to PolarGel-M, PolarGel-L offers excellent resolution of
lower molecular weight polymers such as condensation polymers from step
growth polymerization. Packed with material of the same chemistry as
PolarGel-M, the new PolarGel-L column is also designed for the analysis of
polar compounds using both polar eluents and eluents containing solvent
mixtures such as water with high organic content, cementing the PolarGel
product range as the columns of choice for chemists faced with difficult
polymer analyses.
For additional information about these products, please visit
http://www.varianinc.com
Varian, Inc. is a leading worldwide supplier of scientific instruments
and vacuum technologies for life science and industrial applications. The
company provides complete solutions, including instruments, vacuum
products, laboratory consumable supplies, software, training and support
through its global distribution and support systems. Varian, Inc. employs
approximately 3,900 people worldwide and operates manufacturing facilities
in North America, Europe and Asia Pacific. Varian, Inc. had fiscal year
2007 sales of $921 million, and its common stock is traded on the NASDAQ
Global Select Market under the symbol, "VARI." Further information is
available on the company's Web site: http://www.varianinc.com.
For More Information, Contact:
Public Relations
Varian, Inc.
650.424.3845
pr@varianinc.com
SOURCE Varian, Inc.
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Related links:
http://www.varianinc.com
CONTACT:
Public Relations of Varian, Inc.,
+1-650-424-3845, pr@varianinc.com
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