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Vertex Pharmaceuticals Announces Webcast of its Presentation at the 2006 Bear Stearns Biotech West Coast Confab

    CAMBRIDGE, Mass., March 20 /PRNewswire-FirstCall/ -- Vertex
Pharmaceuticals Incorporated (Nasdaq: VRTX) will webcast its corporate
presentation at the 2006 Bear Stearns Biotech West Coast Confab.  The
presentation and discussion will be delivered by Ian Smith, Vertex's Executive
Vice President and Chief Financial Officer, on Thursday, March 23, 2006 at
5:30 p.m. PST (8:30 p.m. EST).
    The presentation and discussion will be webcast live and may be accessed
by visiting Vertex's website at http://www.vrtx.com.  A replay of the webcast
will also be available on the Company's website until April 6, 2006.  To
access the webcast, go to Vertex's website and select '2006 Bear Biotech West
Coast Confab.'  To ensure a timely connection to the webcast, it is
recommended that users register at least 15 minutes prior to the scheduled
webcast.

    About Vertex
    Vertex Pharmaceuticals Incorporated is a global biotechnology company
committed to the discovery and development of breakthrough small molecule
drugs for serious diseases.  The Company's strategy is to commercialize its
products both independently and in collaboration with major pharmaceutical
companies.  Vertex's product pipeline is principally focused on viral
diseases, inflammation, autoimmune diseases and cancer.  Vertex co-promotes
the HIV protease inhibitor, Lexiva, with GlaxoSmithKline.
    Lexiva is a registered trademark of the GlaxoSmithKline group of
companies.
    Vertex's press releases are available at http://www.vrtx.com.

    Vertex Contact:
    Lora Pike, Manager, Investor Relations, (617) 444-6755


SOURCE Vertex Pharmaceuticals Incorporated




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    CONTACT:
    Lora Pike, Manager, Investor Relations, of
    Vertex Pharmaceuticals Incorporated, +1-617-444-6755