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Vertex Pharmaceuticals Announces the Date of its First Quarter 2006 Financial Results Conference Call and Webcast

    CAMBRIDGE, Mass., April 5 /PRNewswire-FirstCall/ -- Vertex
Pharmaceuticals Incorporated (Nasdaq: VRTX) will announce its first quarter
2006 financial results on Tuesday, April 25, 2006 after the financial
markets close. The Company will host a conference call at 5:00 p.m. EDT.
The conference call also will be webcast.
    The live webcast will be available to all interested parties through
Vertex's website, http://www.vrtx.com, and will be archived on the
Company's website until May 9, 2006. To access the webcast, go to the
investor site and select 'Events & Presentations.' To ensure a timely
connection, it is recommended that users register at least 15 minutes prior
to the scheduled webcast.
    About Vertex
    Vertex Pharmaceuticals Incorporated is a global biotechnology company
committed to the discovery and development of breakthrough small molecule
drugs for serious diseases. The Company's strategy is to commercialize its
products both independently and in collaboration with major pharmaceutical
companies. Vertex's product pipeline is principally focused on viral
diseases, inflammation, autoimmune diseases and cancer. Vertex co-promotes
the HIV protease inhibitor, Lexiva, with GlaxoSmithKline.
    Lexiva is a registered trademark of the GlaxoSmithKline group of
companies.
    Vertex's press releases are available at http://www.vrtx.com.

    Vertex Contact:
    Lora Pike, Manager, Investor Relations, (617)-444-6755


SOURCE Vertex Pharmaceuticals Incorporated




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    CONTACT:
    Lora Pike, Manager, Investor Relations at
    Vertex, +1-617-444-6755