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Biopure Appoints New Independent Auditor

    CAMBRIDGE, Mass., April 10 /PRNewswire-FirstCall/ -- Biopure
Corporation (Nasdaq: BPUR) announced today that it has engaged Vitale,
Caturano & Company, Ltd as its independent auditor.

    The audit committee of Biopure's board of directors made its selection
after a review of audit firms that had expertise with public clients of
Biopure's size and requirements.

    Based in Boston, Massachusetts, Vitale, Caturano & Company, Ltd. is a
large, regional registered public accounting firm. Vitale, Caturano &
Company replaces Ernst & Young, LLP.

    Biopure Corporation

    Biopure Corporation develops, manufactures and markets pharmaceuticals,
called oxygen therapeutics, that are intravenously administered to deliver
oxygen to the body's tissues. Hemopure(R) [hemoglobin glutamer - 250
(bovine)], or HBOC-201, is approved for sale in South Africa for the
treatment of surgical patients who are acutely anemic. Biopure's veterinary
product Oxyglobin(R) [hemoglobin glutamer - 200 (bovine)], or HBOC-301, the
only oxygen therapeutic approved for marketing by both the U.S. Food and
Drug Administration and the European Commission, is indicated for the
treatment of anemia in dogs. Biopure has sold approximately 200,000 units
of Oxyglobin since 1998.


Contact: Tiana Gorham Biopure Corporation (617) 234-6826 IR@biopure.com
SOURCE Biopure Corporation




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    CONTACT:
    Tiana Gorham of Biopure Corporation,
    +1-617-234-6826, IR@biopure.com