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Abgenix Reports First Quarter Results

                  R. Scott Greer Named Chairman of the Board

    FREMONT, Calif., April 25 /PRNewswire/ -- Abgenix, Inc. (Nasdaq: ABGX)
reported a net loss of $3.4 million or $0.09 per share for the quarter ended
March 31, 2000, compared with a net loss of $5.4 million or $0.22 per share
for the quarter ended March 31, 1999. Revenues for the quarter, including
interest income, were $6.3 million compared to $0.4 million in 1999. Deferred
revenues increased during the quarter from $3.8 million to $13.4 million. The
company ended the first quarter with $568 million in cash, cash equivalents
and marketable securities.

    First quarter company highlights included:

    -- Initiating a multi-center Phase II clinical trial with ABX-IL8 in
       psoriasis;
    -- Forming XenoMouse(TM) technology deals with new partners, Elan and
       Gliatech;
    -- Establishing a strategic alliance with Corixa, which will contribute up
       to six antigen targets a year to the collaboration;
    -- Expanding our existing collaboration with Pfizer to include up to five
       product candidates;
    -- Dramatically expanding our collaboration with Millennium, whereby they
       now have broad access to XenoMouse technology for potentially a large
       number of genomics-based targets; and
    -- Raising approximately $500 million net proceeds in the company's
       follow-on public offering.

    "In the first quarter of the new millennium, we continued to build and
advance our proprietary product pipeline, expanded our roster of corporate
collaborations and completed one of the largest public financings in the
biotech industry," said R. Scott Greer, chairman and CEO of Abgenix. "We now
have both the capital and the disease target sources to generate a continuing
stream of antibody product candidates."
    In other news, Abgenix announced today that R. Scott Greer, the company's
president and chief executive officer, has been appointed chairman of the
board of directors replacing Stephen A. Sherwin, M.D., who has served as
chairman since the company's founding in 1996. Dr. Sherwin will continue as a
director of the board.
    "Dr. Sherwin, the chairman and chief executive officer of Cell Genesys,
Inc., our parent company, played a key role in the development of our core
business and was a co-founder of Abgenix," stated Mr. Greer. "We are grateful
for his guidance as chairman over the past four years and look forward to his
continuing service on our board of directors."
    "The appointment of Scott Greer as chairman recognizes the strong
leadership he has provided to Abgenix during its first four years," stated Dr.
Sherwin. "During this time, Abgenix has carried out multiple successful
financings, moved three products into clinical trials, and formed
collaborations with eighteen companies."
    Abgenix was created as a wholly owned subsidiary of
Cell Genesys (Nasdaq: CEGE) in July 1996. Since its founding, Abgenix has
raised over $900 million in private and public equity financings, including
approximately $210 million for Cell Genesys. Currently, Cell Genesys owns
approximately 12% of Abgenix's outstanding shares.
    Abgenix is a biopharmaceutical company that develops and intends to
commercialize antibody therapies for the treatment of such conditions as
transplant-related diseases, inflammatory and autoimmune disorders,
cardiovascular disease, infectious diseases, and cancer.  For more information
on Abgenix, visit the company's Web site at http://www.abgenix.com.
    Abgenix developed XenoMouse technology to enable the rapid generation of
high affinity, fully human antibody product candidates to essentially any
disease target appropriate for antibody therapy. Abgenix has collaborative
arrangements with multiple pharmaceutical, genomics and biotechnology
companies involving its XenoMouse technology. In addition, Abgenix has
multiple proprietary antibody product candidates under development internally,
three of which are in human clinical trials for graft-versus-host disease,
psoriasis, rheumatoid arthritis, and cancer.

                                                          Three months ended
                                                              March 31
                                                         2000           1999
    Revenues:                                                 (unaudited)
    Contract revenues                                   $1,965           $--
    Interest income                                      4,341           395
      Total revenues                                     6,306           395
    Costs and Expenses:
      Research and development                           7,214         4,567
      General and administrative                         1,584         1,084
      Amortization of intangible assets                    777            --
      Interest expense                                     114           133
      Equity in losses in Xenotech joint venture            --             8
        Total costs and expenses                         9,689         5,792
    Net loss                                          ($3,383)      ($5,397)

    Net loss per share*                                ($0.09)       ($0.22)
    Shares used in computing net loss per share*        37,250        24,274

                                                      March 31,   December 31,
    Balance Sheet                                       2000            1999
    (in thousands)                                   (unaudited)
    Cash, cash equivalents and
     marketable securities                            $568,003       $58,012
    Property and equipment, net                          5,253         5,300
    Long-term investment                                39,176        29,225
    Intangible assets, net                              45,814        46,591
    Other assets                                         4,825         9,413
    Total assets                                       663,071       148,541
    Deferred revenue                                    13,367         3,767
    Other current liabilities                            6,286         7,143
    Long-term debt and other                               296           571
    Stockholders' equity                               643,122       137,060
    Total liabilities and stockholders' equity        $663,071      $148,541

    * After giving effect to the two for one stock split effective
      April 6, 2000

    Statements made in this press release about Abgenix's XenoMouse
technology, product development activities and collaborative arrangements
other than statements of historical fact, are forward looking statements and
are subject to a number of uncertainties that could cause actual results to
differ materially from the statements made, including risks associated with
the success of clinical trials, the progress of research and product
development programs, the regulatory approval process, competitive products,
future capital requirements and the extent and breadth of Abgenix's patent
portfolio. Please see Abgenix's public filings with the Securities and
Exchange Commission for information about risks that may affect Abgenix.


SOURCE Abgenix, Inc.




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    CONTACT:
    Kurt Leutzinger, Chief Financial Officer of
    Abgenix Inc., 510-608-6575