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Vertex Pharmaceuticals to Webcast its 2006 Annual Meeting of Stockholders

    CAMBRIDGE, Mass., May 4 /PRNewswire-FirstCall/ -- Vertex
Pharmaceuticals Incorporated (Nasdaq: VRTX) will webcast its 2006 Annual
Meeting of Stockholders on Thursday, May 11, 2006. Joshua Boger, Ph.D.,
Chairman, President and Chief Executive Officer of Vertex, will host the
webcast, which will begin at approximately 9:30 a.m. EDT.
    The live webcast may be accessed by visiting the Vertex website at
http://www.vrtx.com. A replay of the webcast will also be available on the
Company's website until May 25, 2006. To access the webcast, go to Vertex's
website and select '2006 Annual Meeting of Stockholders' from the 'Events
Calendar.' To ensure a timely connection, it is recommended that users
register at least 15 minutes prior to the scheduled webcast.
    About Vertex
    Vertex Pharmaceuticals Incorporated is a global biotechnology company
committed to the discovery and development of breakthrough small molecule
drugs for serious diseases. The Company's strategy is to commercialize its
products both independently and in collaboration with major pharmaceutical
companies. Vertex's product pipeline is principally focused on viral
diseases, inflammation, autoimmune diseases and cancer. In collaboration
with GlaxoSmithKline, Vertex co-promotes the HIV protease inhibitor,
Lexiva.
    Lexiva is a registered trademark of the GlaxoSmithKline group of
companies.
    Vertex's press releases are available at http://www.vrtx.com.

    Vertex Contact:
    Lora Pike, Manager, Investor Relations, (617) 444-6755


SOURCE Vertex Pharmaceuticals Incorporated




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    CONTACT:
    Lora Pike, Manager, Investor Relations of
    Vertex Pharmaceuticals Incorporated, +1-617-444-6755