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Vertex Pharmaceuticals Announces Webcasts of its Presentations at Two Investor Conferences

    CAMBRIDGE, Mass., May 26 /PRNewswire-FirstCall/ -- Vertex
Pharmaceuticals Incorporated (Nasdaq: VRTX) will webcast its presentations
at Sanford Bernstein's 22nd Annual Strategic Decisions Conference and the
Bear Biotech Boston Confab.
    Joshua Boger, Ph.D., President and Chief Executive Officer of Vertex,
will present at the Sanford Bernstein Strategic Decisions Conference on
Wednesday, May 31, 2006 at 8:00 a.m. EDT.
    Ian Smith, Executive Vice President and Chief Financial Officer, and
John Alam, M.D., Executive Vice President, Medicines Development and Chief
Medical Officer at Vertex, will present at the Bear Biotech Boston Confab.
The presentation and discussion will also be conducted on Wednesday, May
31, 2006 and will take place at 5:40 p.m. EDT.
    The presentations will be webcast live and may be accessed by visiting
the Vertex website at http://www.vrtx.com. A replay of the webcasts will
also be available on the Company's website for two weeks following the
presentations. To access the webcasts, go to Vertex's website and select
the 'Sanford Bernstein 22nd Annual Strategic Decisions Conference' or the
'Bear Biotech Boston Confab' from the 'Events Calendar.' To ensure a timely
connection, it is recommended that users register at least 15 minutes prior
to the scheduled webcast.
    About Vertex
    Vertex Pharmaceuticals Incorporated is a global biotechnology company
committed to the discovery and development of breakthrough small molecule
drugs for serious diseases. The Company's strategy is to commercialize its
products both independently and in collaboration with major pharmaceutical
companies. Vertex's product pipeline is principally focused on viral
diseases, inflammation, autoimmune diseases and cancer. In collaboration
with GlaxoSmithKline, Vertex co-promotes the HIV protease inhibitor,
Lexiva.
    Lexiva is a registered trademark of the GlaxoSmithKline group of
companies.
    Vertex's press releases are available at http://www.vrtx.com.

    Vertex Contact:
    Lora Pike, Manager, Investor Relations, (617) 444-6755


SOURCE Vertex Pharmaceuticals Incorporated




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    CONTACT:
    Lora Pike, Manager, Investor Relations of
    Vertex Pharmaceuticals Incorporated, +1-617-444-6755