PRINCETON, N.J., June 1 /PRNewswire/ -- Laureate Pharma, a
biopharmaceutical development and protein production company, is sponsoring
a live webcast at 2PM EDT on June 8 on "Development Of A Third-Generation
Antibody For Therapy Of Prostate Cancer." The free webcast, presented by
BioPharm International, will include presentations by experts from Cytogen
Corporation, Laureate Pharma, and Memorial Sloan Kettering Cancer Center.
(Logo: http://www.newscom.com/cgi-bin/prnh/20020723/LPHARMLOGO )
The development of radiolabeled therapeutic antibodies is a
sophisticated process involving both selection of an isotope with optimal
radiation properties and secure mechanisms of isotope attachment. Such
antibodies have enhanced potency in cancer therapy, directing radiation to
specific areas of disease. Process development and cGMP manufacturing of
these entities for clinical trials pose logistical challenges best
addressed by a team approach, involving more than one company, on the route
from "concept to clinic." The webcast will feature the team of scientists
from Cytogen and Laureate Pharma who overcame challenges and produced a new
radiolabeled antibody therapeutic that will enter clinical trials next
month. The novel agent combines a PSMA- specific targeting antibody with a
high-affinity chelator and a beta-emitting isotope with desirable
properties for irradiation of metastatic sites in prostate cancer.
During the webcast, the presenters will be discussing the critical
decisions they had to make along the development path including:
-- Selection of the targeting antibody
-- The rationale for choice of radioisotope
-- Design and properties of chelators for optimal attachment of radio-
metallic isotopes to antibodies
-- Understanding process development and cGMP manufacturing of
radiolabeled antibodies
-- Preclinical design considerations for radiolabeled antibodies
They will also address the value of a multi-company collaboration to
address logistical challenges associated with a complex radiolabeled
biopharmaceutical and the value of radiolabeled antibodies in cancer
therapy.
The audience will have an opportunity to pose questions to the panel of
experts during a real-time Q&A session at the conclusion of the webcast.
Those who are interested in participating in the webcast are encouraged to
register for the event at http://www.laureatepharma.com or
http://www.BioPharmInternational.com/RadioLabels.
About Laureate Pharma, Inc.
Laureate Pharma, http://www.laureatepharma.com, located in Princeton,
NJ, provides superior bioprocessing services that accelerate new products
from development through production. Laureate Pharma is a partner company
of Safeguard Scientifics, Inc. (NYSE: SFE), http://www.safeguard.com, which
provides growth capital, strategic, operational and management resources to
Laureate Pharma. For more information contact Michael Cavanaugh, Vice
President Sales, Marketing, and Business Development, (609) 919-3400 or
info@laureatepharma.com.
SOURCE Laureate Pharma, Inc.
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Related links: http://www.laureatepharma.com http://www.BioPharmInternational.com/RadioLabels http://www.safeguard.com
Photo Notes:http://www.newscom.com/cgi-bin/prnh/20020723/LPHARMLOGO PRN Photo Desk photodesk@prnewswire.com
CONTACT: Michael Cavanaugh, Vice President Sales, Marketing, and Business Development, Laureate Pharma, +1-609-919-3400 or info@laureatepharma.com
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