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Researchers Gather to Address New Tools in Development for Breast Cancer Detection

     First Meeting of Avon Foundation Breast Cancer Prevention Research
            Initiative Taking Place July 10-11 in San Francisco

    SAN FRANCISCO, July 9 /PRNewswire/ -- Leading breast cancer researchers
from across the country are convening in San Francisco July 10-11 for the
first meeting of the Avon Foundation Breast Cancer Prevention Research
Initiative. The two-day meeting, taking place at the Westin St. Francis,
brings together researchers from leading institutions who are focused on
the remarkable research in breast cancer biomarkers that has taken place
over the last three years. The goal is to use the latest biomarker
knowledge to develop new tests for the earliest detection and diagnostics
in breast cancer -- ultimately leading to monitor the earliest changes in
healthy breasts before cancer occurs.

    Current breast cancer screening relies primarily on imaging, including
mammography, ultrasound and MRI. While these diagnostic modalities provide
the opportunity for detection and successful treatment, the aim of the new
Avon Foundation-funded research initiative is to pursue non-imaging
techniques that offer compelling and innovative opportunities. In support
of this novel direction, 12 projects were selected through a competitive
application process, with a total of $7.6 million awarded in support of
their research. The projects, which are focused on fairly simple but
effective methods, range from developing a new "band-aid" dipstick that
collects fluid from nipple discharge to several projects that attempt to
measure markers in blood to detect the very earliest breast cancer
development.

    The leaders of the research projects are meeting to present preliminary
findings and share ideas in a spirit of collaboration and a shared
commitment to ending breast cancer. Included is one pharmaceutical company,
A&G Pharmaceutical, in addition to the individual medical researchers.

    "The Avon Foundation is proud to support these researchers in their
innovative approaches to breast cancer detection and prevention," stated
Marc Hurlbert, PhD, Director of the Avon Foundation Breast Cancer Crusade.
"Our goal is to advance research that will one day eradicate breast cancer
and, at the same time, facilitate collaboration and sharing. This meeting
is a part of that critical process."


The funded researchers and their research initiatives include: Kim Baltzell, PhD, University of California San Francisco Viruses in breast fluid as possible biomarkers for breast cancer David Gilley, PhD, and Hiromi Tanaka, PhD, Indiana University Telomere dysfunction markers for breast cancer detection Bassem Haddad, MD, Georgetown University Improving the diagnostic power of ductal lavage for early detection of breast cancer by assessing multiple molecular markers in the same specimen
Sam Hanash, MD, PhD, Fred Hutchinson Cancer Research Center Validation of an autoantibody signature for breast cancer Gary Johanning, PhD, University of Texas M.D. Anderson Cancer Center Breast cancer screening by assessing serum HERV-K antibodies and RNA Celina Kleer, MD, University of Michigan Enhancer of Zeste2 as a biomarker of preneoplastic progression in the breast Susan Love, MD, Dr. Susan Love Research Foundation Development of a breast fluid test to identify women at risk for breast cancer Emanuel Petricoin, PhD, George Mason University Phosphopeptide biomarkers for early breast cancer detection in women with mammographically occult cancer Ginette Serrero, PhD, A&G Pharmaceutical Development of GP88 serum test for early breast cancer diagnosis Charles Streckfus, DDS, MA, FAOM, University of Texas Health Sciences Center at Houston Identifying biomarkers for breast cancer detection in saliva Sara Sukumar, PhD, Johns Hopkins / Seema Khan, MD, Northwestern Gene methylation and estradiol levels in random FNA samples as biomarkers of breast cancer risk
Thea Tlsty, PhD, University of California San Francisco Molecular markers that predict future formation of malignant breast cancer The Breast Cancer Prevention Research Initiative is one of many programs of the Avon Foundation Breast Cancer Crusade. The Avon Crusade first launched in 1992, and, through 2007, more than $525 million has been raised in over 50 countries worldwide to advance access to care and finding a cure for breast cancer, with a focus on the medically underserved. Funding is awarded to beneficiaries ranging from leading cancer centers to community-based nonprofit organizations for breast cancer outreach and education; screening and diagnostics; access to treatment; support services; and medical research. The Avon Crusade is the largest initiative of the Avon Foundation, a 501(c)(3) public charity with a mission to improve the lives of women, with a focus on breast cancer and domestic violence. For more information: avonfoundation.org. Also taking place this week in San Francisco is the sixth annual Avon Walk for Breast Cancer, a weekend-long, 39-mile walk which will raise millions more dollars for the breast cancer cause. The Avon Walk San Francisco, a project of the Avon Foundation, is the sixth of nine Avon Walk events this year. The first five raised more than $30 million. Initial grants are awarded to local breast cancer organizations at the conclusion of each event, ensuring that funds immediately benefit the community, and additional grants are awarded nationwide throughout the year. The Avon Walk San Francisco commences early Saturday morning in Golden Gate Park and ends with a Closing Ceremony back at the same location at 3:00 pm Sunday. The event is expected to exceed last year's total of $5.6 million raised. For more information: avonwalk.org.
SOURCE Avon Foundation




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Related links:
  • http://www.avon.com
  • http://www.avonfoundation.org
  • http://avonwalk.org
  • http://www.prnewswire.com/comp/079575.html /
    CONTACT:
    Susan Arnot Heaney, Avon Foundation,
    +1-917-209-9518, Susan.heaney@avonfoundation.org