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Quintiles Reports 2nd Quarter Net Revenue of $537 Million, Up 26%

     - Record reported backlog of $2.8 billion
     - $1.1 billion in net new business wins for 1st half 2005
     - 26% net revenue increase

    RESEARCH TRIANGLE PARK, N.C., Aug. 12 /PRNewswire/ -- Quintiles
Transnational Corp. today announced financial results for the quarter ended
June 30, 2005.  Net revenue for second quarter 2005 was $537.4 million, an
increase of 26% from net revenue of $425.8 million for second quarter 2004.
Contribution from Quintiles' Product Development and Commercial Services
groups totaled $243.0 million in second quarter 2005, up 28% from $189.7
million for second quarter 2004.
    Net loss for second quarter 2005 was $44.2 million, after $72.0 million in
non-cash impairment charges and $10.7 million of charges relating to the
company's previously announced restructuring program, compared to a net loss
of $10.1 million in second quarter 2004.  The 2005 impairment charges
primarily relate to Quintiles' pending sale, as previously announced, of its
Preclinical Services, Pharmaceutical Sciences and Clinical Trial Supplies
businesses to Aptuit Inc. for approximately $125 million.  An agreement has
been reached and the transaction is expected to close in third quarter 2005.
The net loss in second quarter 2004 included gains of $34.7 million when
Mitsui & Co., Ltd., (Mitsui) became a 20% shareholder in Quintiles
Transnational Japan K.K. (Quintiles Japan) in June 2004.
    Excluding the restructuring and impairment charges, second quarter 2005
earnings before interest, taxes, depreciation and amortization (EBITDA)
totaled $60.5 million.  Second quarter 2004 EBITDA was $17.9 million,
excluding the impairment charges and the gains of $34.7 million related to
Mitsui's investment in Quintiles Japan.  Including the restructuring and
impairment charges, second quarter 2005 EBITDA was a loss of $22.2 million.
Second quarter 2004 EBITDA was $51.8 million, including the impairment charges
and Mitsui gains.  See Schedule 3 for a reconciliation of the above amounts to
net loss.  A reconciliation of EBITDA to net loss is also included in the
company's form 10-Q on file with the Securities and Exchange Commission.
    For the first half of 2005, net new business totaled approximately $1.1
billion versus $954.5 million for the same period in 2004.  Total backlog as
of June 30, 2005, was approximately $2.8 billion, compared with approximately
$2.2 billion at June 30, 2004.
    "These strong results illustrate our success in advancing Quintiles'
strategic priorities -- understanding customer needs, improving processes,
making our organizational structure more efficient, and empowering employees,"
said Quintiles Transnational Chairman and Chief Executive Officer Dennis
Gillings, CBE.  "The Aptuit agreement is a winning strategic move for
Quintiles.  By working with Aptuit to address customers' early development
services needs, Quintiles can focus more resources on our core clinical
development and commercial services.
    "I'd like to congratulate our employees for their hard work and focus in
helping Quintiles and our customers succeed."
    Quintiles Transnational Executive Vice President and Chief Financial
Officer John Ratliff said: "We achieved 26% net revenue growth and ended the
quarter with a record reported backlog of $2.8 billion. Our SG&A (sales,
general and administrative) expenses declined to 31% of net revenue from 37%
year-over-year.  We continue to hire billable staff as our project workload
grows while we reduce non-billable positions.
    "All of our efforts have contributed to substantially improved operating
profits in our contract research and contract sales services groups and our
PharmaBio Development strategic investment group.  Our business model is
working and I'm very pleased with our solid second quarter performance."
    As of June 30, 2005, Quintiles had cash and cash equivalents of $298.3
million.  As of June 30, 2005, Quintiles had 17,736 full-time equivalent
employees versus 16,660 on the same date in 2004.
    As part of Quintiles' normal closing process for second quarter 2005, the
company determined that assets of its Early Development and Packaging (EDP)
business, composed of the company's Preclinical, Pharmaceutical Sciences and
Clinical Trials Supplies businesses, were impaired.  The determination of the
impairment in June 2005 resulted from the increased probability of selling the
assets of the EDP business prior to the end of the assets' estimated useful
life.  As a result, the company recognized a $65.8 million impairment on the
EDP long-lived assets during second quarter 2005.
    Quintiles Transnational's second quarter 2005 financial briefing will be
held at 1:00 p.m. EDT on Friday, Aug. 12, and will be broadcast live over the
Web.  The webcast or replay, which will be available through 5:00 p.m. EDT
Friday, Sept. 2, can be accessed at
http://www.quintiles.com/corporate_info/broadcast_center.
    Quintiles helps improve healthcare worldwide by providing a broad range of
professional services, information and partnering solutions to the
pharmaceutical, biotechnology and healthcare industries. Headquartered near
Research Triangle Park, North Carolina, Quintiles has offices in 50 countries
and is the world's leading pharmaceutical services organization. For more
information visit the company's Web site at http://www.quintiles.com.
    The schedules attached to this release are an integral part of this
release.  Information in this press release contains "forward looking
statements" about Quintiles.  These statements involve risks and uncertainties
that could cause actual results to differ materially, including, without
limitation, the ability to maintain large customer contracts or to enter into
new contracts, changes in trends in the pharmaceutical industry, the risk that
the market for our products and services will not grow as we expect, the risk
that our PharmaBio transactions will not generate revenue or profit at the
rate or levels we anticipate or that royalty revenues under the PharmaBio
agreements may not be adequate to offset Quintiles' upfront and ongoing
expenses in providing sales and marketing services or in making milestone and
marketing payments, our ability to fulfill our obligations under our financing
arrangements and the potential impact on our operations, our ability to
efficiently distribute backlog among project management groups and match
demand to resources, actual operating performance, variation in the actual
savings and operating improvements resulting from previous restructurings, the
ability to operate successfully in new lines of business, and the possibility
that the sale of the EDP business may be delayed or fail to close.  Additional
factors that could cause actual results to differ materially are discussed in
the company's recent filings with the Securities and Exchange Commission,
including but not limited to its Annual Report on Form 10-K, its Form 8-Ks,
and its other periodic reports, including Form 10-Qs.



    Schedule 1 of 3
    Condensed Consolidated Statements of Income
    (Unaudited)



                                     Three     Three       Six        Six
                                     months    months     months     months
                                     ended     ended      ended      ended
                                    June 30,  June 30,   June 30,   June 30,
                                      2005      2004       2005       2004
    In thousands

    Net revenues                    $537,447  $425,766  $1,029,803   $848,960
    Add:  reimbursed service costs   131,298    82,306     241,983    164,765

    Gross revenues                   668,745   508,072   1,271,786  1,013,725

    Costs, expenses and other:
         Costs of revenues           468,973   372,062     905,606    728,664
         Selling, general and
          administrative             167,959   159,027     322,437    314,688
         Interest expense (income),
          net                         12,175    14,576      29,614     29,195
         Other expense (income),
          net                          2,764       318       2,888     (2,873)
         Restructuring                10,676       -        19,679        -
         Impairments                  72,033       881      72,467        881
         Transaction expense, net        -         -        (2,666)       -
         Gain on sale of portion of
          an investment in a
          subsidiary                     -     (24,688)        -      (24,688)
         Non-operating gain on
          change of interest
          transaction                    -     (10,030)        -      (10,030)
                                     734,580   512,146   1,350,025  1,035,837

    Loss before income taxes         (65,835)   (4,074)    (78,239)   (22,112)
    Income tax (benefit) expense
     (includes $31,521 of income
     tax benefit related to
     American Jobs Creation Act of
     2004 for the six months ended
     June 30, 2005                   (22,996)   14,133     (56,016)    13,408

    Loss before minority interests
     and equity in (losses)
     earnings of unconsolidated
     affiliates                      (42,839)  (18,207)    (22,223)   (35,520)
    Equity in (losses) earnings of
     unconsolidated affiliates          (329)       45        (528)       (23)
    Minority interests                  (995)     (246)     (2,068)      (433)

    Loss from continuing operations  (44,163)  (18,408)    (24,819)   (35,976)

    Income from discontinued
     operation                           -       8,280         -       10,141

    Net loss                        $(44,163) $(10,128)   $(24,819)  $(25,835)



    Consolidated Balance Sheet Data
    (Unaudited)
                                               June 30,        December 31,
                                                 2005              2004
    In millions

    Cash, cash equivalents and debt
     investments                                      $311              $548
    Investments in marketable equity
     securities                                         33                24
    Investments in non-marketable equity
     securities and loans                               56                56
    Investments in unconsolidated
     affiliates                                        120               121
    Working capital                                    175               316
    Total assets                                     1,773             2,048
    Debt including current portion                     639               795
    Shareholders' equity                               519               568



    Schedule 2 of 3
    Segment Information
    (Unaudited)

                                    Three     Three        Six        Six
                                    months    months      months     months
                                    ended     ended       ended      ended
                                   June 30,  June 30,    June 30,   June 30,
                                     2005      2004        2005       2004
    In thousands

    Service revenues:
         Product development       $331,925  $268,363    $642,203    $531,047
         Commercial services        193,280   158,859     377,383     305,846
         Eliminations               (25,333)   (8,596)    (51,644)    (14,879)
    Total net service revenues      499,872   418,626     967,942     822,014

    PharmaBio Development
         Commercial rights and
          royalties                  38,458    15,155      64,702      30,741
         Investment                    (883)   (8,015)     (2,841)     (3,795)
    Total PharmaBio Development      37,575     7,140      61,861      26,946

    Total net revenues              537,447   425,766   1,029,803     848,960
    Reimbursed service costs        131,298    82,306     241,983     164,765

    Gross revenues                 $668,745  $508,072  $1,271,786  $1,013,725


    Contribution (revenues less
     cost of revenues excluding
     depreciation and amortization
     expense except as noted
     below):
         Product development       $164,757  $128,353    $314,403    $256,415
         Commercial services         78,158    61,310     145,758     115,865
         PharmaBio Development
          (includes amortization
          and depreciation expense
          noted below)              (13,954)  (21,497)    (36,043)    (22,156)
    Total contribution             $228,961  $168,166    $424,118    $350,124


    Depreciation and amortization
     expense (excluded from
     contribution except as noted
     below):
         Product development        $20,405   $21,182     $40,476     $42,772
         Commercial services          7,611     7,823      15,144      16,007
         PharmaBio Development
          (included in
          contribution)               3,556     1,015       4,233       1,819
         Corporate                    1,173     3,151       2,318       6,284
    Total depreciation and
     amortization expense           $32,745   $33,171     $62,171     $66,882



    Schedule 3 of 3
    EBITDA Reconciliation
    (Unaudited)

                                         Three     Three     Six        Six
                                         months    months   months     months
                                         ended     ended    ended      ended
                                        June 30,  June 30, June 30,   June 30,
                                         2005      2004      2005       2004
    In millions

    Net revenues                            $537.4  $425.8  $1,029.8   $849.0
    Add:  reimbursed service costs           131.3    82.3     242.0    164.8

    Gross revenues                           668.7   508.1   1,271.8  1,013.7

    Costs, expenses and other:
         Costs of revenues                  (469.0) (372.1)   (905.6)  (728.7)
         Selling, general and
          administrative                    (168.0) (159.0)   (322.4)  (314.7)
         Other (expense) income, net          (2.8)   (0.3)     (2.9)     2.9
         Transaction expense, net              0.0     0.0       2.7      0.0
         Depreciation and amortization        32.7    33.2      62.2     66.9
         Equity in earnings (losses) of
          unconsolidated affiliates           (0.3)    0.0      (0.5)    (0.0)
         Minority interests                   (1.0)   (0.2)     (2.1)    (0.4)
         Income from discontinued operation    0.0     8.3       0.0     10.1

    EBITDA, excluding impairments,
     restructuring charges and Mitsui gains   60.5    17.9     103.1     49.8

         Impairments                         (72.0)   (0.9)    (72.5)    (0.9)
         Restructuring                       (10.7)    0.0     (19.7)     0.0
         Gain on sale of portion of an
          investment in a subsidiary           0.0    24.7       0.0     24.7
         Non-operating gain on change of
          interest transaction                 0.0    10.0       0.0     10.0

    EBITDA                                   (22.2)   51.8      11.0     83.7

    Depreciation and amortization            (32.7)  (33.2)    (62.2)   (66.9)
    Interest expense, net                    (12.2)  (14.6)    (29.6)   (29.2)
    Income tax benefit (expense)              23.0   (14.1)     56.0    (13.4)

    Net loss                                $(44.2) $(10.1)   $(24.8)  $(25.8)


SOURCE Quintiles Transnational Corp.




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    CONTACT:
    Pat Grebe, Media Relations,
    media.info@quintiles.com, or Greg Connors, Investor Relations,
    invest@quintiles.com, of Quintiles Transnational Corp.,
    +1-919-998-2000