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Northfield Laboratories Reports Second Quarter Results; Phase III Trials of Blood Substitute Continue

    EVANSTON, Ill., Jan. 21 /PRNewswire/ -- Northfield Laboratories Inc.
(Nasdaq: NFLD), today reported a loss as anticipated for its second fiscal
quarter and first half ended November 30, 1997.
    The company, which is conducting Phase III trials of a blood substitute,
reported a loss of $1,393,000, or 10 cents per share, for the second quarter,
compared with a loss of $1,139,000, or 8 cents per share, in the year-earlier
period.  For the first half of the fiscal year, the company reported a loss of
$2,723,000, or 19 cents per share, versus $2,109,000, or 15 cents per share,
in the prior year.  As a development stage company, Northfield has no
revenues.
    The larger loss is primarily due to increased expenses related to the
company's Phase III clinical trials, as well as preparatory and analysis work
for a commercial manufacturing facility.  At the close of the quarter, the
company reported shareholders' equity of $58.6 million, with $55.8 million in
cash and marketable securities.
    Richard DeWoskin, chairman and chief executive officer, said the company
continues to make progress in Phase III clinical trials of PolyHeme, the last
series of clinical trials prior to commercial introduction of a product.
PolyHeme is the only blood substitute undergoing clinical trials that has been
tested at large enough dosages to be considered a substitute for acute blood
loss in trauma and surgical settings, he noted.  As a result of the process
used to manufacture the blood substitute, essentially a solution of
polymerized hemoglobin, PolyHeme has a longer shelf life than blood, requires
no cross matching and does not transmit disease, he added.
    Northfield Laboratories was founded in 1985.  The Company is headquartered
in Evanston, Illinois, and its stock is traded on the Nasdaq National Market
System under the symbol NFLD.

       Northfield Laboratories Inc.
    (a company in the development stage)

    Statements of Operations
    Three and six months ended November 30, 1997 and November 30, 1996
    (In thousands except per share data)

                             Three months ended         Six months ended
                            Nov. 30,      Nov. 30,     Nov. 30,     Nov. 30,
                               1997          1996         1997         1996
                         (unaudited)   (unaudited)  (unaudited)  (unaudited)

    Revenues - license income  $ --         $ --        $ --       $ --

    Costs and expenses:
      Research and development  1,565       1,419       3,151       2,679
      General and administrative  622         541       1,204       1,080
                                2,187       1,960       4,355       3,759
    Other income and expense:
      Interest income             794         821       1,632       1,650
      Interest expense             --          --          --          --
                                  794         821       1,632       1,650

    Net loss                  $(1,393)    $(1,139)    $(2,723)    $(2,109)

    Net loss per share         $(0.10)     ($0.08)     $(0.19)     $(0.15)

    Shares used in calculation of
      per share data           14,092      13,985      14,092      13,893

    Northfield Laboratories Inc.
    (a company in the development stage)

    Balance Sheets
    November 30, 1997 (unaudited) and May 31, 1997
    (In thousands)

                                                    November 30,    May 31,
    Assets                                                 1997       1997

    Current assets:
      Cash                                              $10,175    $21,367
     Short-term marketable securities                    45,657     38,927
     Prepaid expenses                                       222        335
     Other current assets                                   242        418
     Total current assets                                56,296     61,047

    Property, Plant and equipment, net                    3,155      1,263
    Other assets                                             28         33
    Total assets                                        $59,479    $62,343

    Liabilities and Shareholders' Equity
    Current liabilities:
      Accounts payable                                     $448       $656
      Accrued expenses                                      102        122
      Accrued compensation and benefits                     264        176
    Total current liabilities                               814        954

    Other liabilities                                        92         94
    Total liabilities                                       906      1,048

    Shareholders' equity:
      Capital Stock                                         141        141
      Additional paid-in capital                        116,012    116,012
      Deficit accumulated during the                    (57,580)   (54,857)
        development stage
      Deferred compensation                                  --         (1)
    Total shareholders' equity                           58,573     61,295

    Total liabilities and
      shareholders' equity                              $59,479    $62,343


SOURCE Northfield Laboratories




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CONTACT:
Richard DeWoskin, Chief Executive Officer of
Northfield Laboratories, 847-864-3500; or Michael Rosenbaum,
General Information, Bess Gallanis, Media Contact, Kathy Brunson,
Analyst-Broker, all of The Financial Relations Board,
312-266-7800