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Dura Pharmaceuticals Announces Financial Results for the Third Quarter of 2000

    SAN DIEGO, Oct. 18 /PRNewswire/ -- Dura Pharmaceuticals, Inc. (Dura)
(Nasdaq: DURA) today reported net losses, including non-recurring charges
totaling $103.2 million, of $98.7 million for the third quarter of 2000 and
$76.8 million for first nine months of 2000.  Net loss per diluted share was
$2.20 for the third quarter and $1.73 for the nine months ended September 30,
2000.  The non-recurring charges pertain to acquired in-process technology
resulting from the acquisition of Spiros Development Corporation II, Inc.
(SDCII), restructuring of Spiros technology programs and expenses resulting
from the pending merger with Elan Corporation, plc (Elan) (NYSE: ELN).
Earnings per diluted share, excluding non-recurring charges, were
$0.09 and $0.56 for the third quarter and first nine months of 2000,
respectively.  This compares to earnings per diluted share, excluding
non-recurring charges, of  $0.13 and $0.47 for the respective periods in 1999.
    Pharmaceutical sales totaled $58 million for the third quarter and
$186.2 million for the first nine months of 2000, representing increases of
7% and 16% over the respective periods last year. Contract revenue generated
primarily from SDCII and Eli Lilly & Company (NYSE: LLY) totaled $12.1 million
for the third quarter and $51.2 million for the first nine months of 2000,
compared to $17.3 million for the third quarter and $50.1 million for the
first nine months of 1999.  Contract revenue from SDCII during July and August
of 2000 totaled $6.9 million and ceased with Dura's acquisition of SDCII on
August 31, 2000. The Company ended the third quarter of 2000 with over
$250 million in cash and short-term investments and generated cash flow from
operations, excluding non-recurring cash charges, of $28 million and
$78 million during the third quarter and first nine months of 2000,
respectively.
    Dura also announced that it is terminating its program initiated in
October 1998 to repurchase up to $50 million of the Company's common stock.
Under this program, Dura repurchased a total of 2.4 million shares of its
common stock at an average price of $11.68 per share.  Substantially all of
these shares were repurchased in 1998.

    Dura Pharmaceuticals, Inc. is a San Diego based specialty pharmaceutical
company that markets and sells prescription products that treat infectious,
respiratory and dermatological diseases.  Dura focuses on products and
transactions that leverage its sales and marketing organization.  Dura also
intends, through the use of collaborative relationships, to develop the
Spiros(R) motorized blisterdisk and Spiros(R) S2 pulmonary drug delivery
systems for the local and systemic delivery of a wide range of medications.
On September 11, 2000, Dura and Elan announced the signing of a definitive
merger agreement for Elan to acquire Dura.  The merger is pending approval by
vote of Dura's shareholders at a special meeting of shareholders which is
scheduled to take place on November 9, 2000.

    Except for the historical and factual information contained herein, the
matters discussed in this press release may contain forward-looking statements
including targets, estimates, plans, expectations, goals and projections,
which involve risks and uncertainties, including Dura's ability to complete
its merger with Elan, risks associated with the creation and successful
operation of a dermatology division, the effectiveness of Dura's sales forces
in promoting its products, Dura's success in acquiring additional products,
risks associated with the successful development and commercialization of the
inhaled insulin product candidate and Dura's Spiros(R) S2 technology, and
other risks detailed from time to time in Dura's filings with the Securities
and Exchange Commission.  Actual results may differ materially from those
projected, including future growth in product sales and earnings.  Any
forward-looking statements represent Dura's judgment as of the time and date
of this release.  Dura disclaims, however, any intent or obligation to update
any such forward-looking statements. Further information about Dura
Pharmaceuticals, Inc. can be found at http://www.durapharm.com.

                       Financial Information to Follow


    CONSOLIDATED STATEMENTS OF OPERATIONS DATA
    (In thousands, except per share data)        (unaudited)

                                    Three Months Ended Nine Months Ended
                                      September 30,      September 30,
                                     2000      1999     2000       1999
    REVENUES:
      Sales                        $58,000   $54,271  $186,207  $160,673
      Contract                      12,127    17,289    51,230    50,140
        Total revenues              70,127    71,560   237,437   210,813

    OPERATING COSTS AND EXPENSES:
      Cost of sales                 13,539    10,467    39,615    31,337
      Clinical, development and
       regulatory                   13,155    13,000    43,967    36,966
      Selling, general and
       administrative               42,726    34,077   115,682    95,145
      Product rights amortization    5,864     5,166    16,779    14,975
      Charges for acquired in-
       process technology,
       restructuring and merger
       expenses                    103,170        --   103,170        --
        Total operating costs
         and expenses              178,454    62,710   319,213   178,423

    OPERATING INCOME (LOSS)       (108,327)    8,850   (81,776)   32,390

    OTHER INCOME (LOSS) - net          654    (3,650)    5,375    (3,717)

    INCOME (LOSS) BEFORE
     INCOME TAXES                 (107,673)    5,200   (76,401)   28,673

    PROVISION (BENEFIT) FOR
     INCOME TAXES                   (8,973)    1,664       400     9,789

    NET INCOME (LOSS)             $(98,700)   $3,536  $(76,801)  $18,884

    NET INCOME (LOSS) PER
     SHARE - diluted                $(2.20)    $0.08    $(1.73)    $0.41

    WEIGHTED AVERAGE NUMBER OF
     COMMON AND COMMON EQUIVALENT
     SHARES - diluted               44,767    45,462    44,478    45,655


    CONSOLIDATED BALANCE SHEET DATA
                                        (unaudited)
                                       September 30,  December 31,
                                           2000           1999

    CASH AND SHORT-TERM INVESTMENTS       $250,246    $274,413
    OTHER CURRENT ASSETS                    55,069      69,093
    LICENSE AGREEMENTS, PRODUCT RIGHTS,
     AND OTHER                             556,599     539,968

      TOTAL ASSETS                        $861,914    $883,474

    CURRENT LIABILITIES                   $105,721     $87,581
    LONG-TERM LIABILITIES                  357,197     354,154
    STOCKHOLDERS' EQUITY                   398,996     441,739

      TOTAL LIABILITIES AND
       STOCKHOLDERS' EQUITY               $861,914    $883,474


    News releases from Dura Pharmaceuticals are available at no charge on
Dura's web site at http://www.durapharm.com and through PR Newswire's On-Call fax
service by calling (800) 758-5804, extension 197051.


SOURCE Dura Pharmaceuticals, Inc.




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    CONTACT:
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    858-457-2553