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Agouron Reports First Quarter 1999 Net Income

    LA JOLLA, Calif., Oct. 20 /PRNewswire/ -- Agouron Pharmaceuticals, Inc.
(Nasdaq: AGPH) today announced net income of $6,890,000, or $.21 per share on
total revenues of $144,937,000 for the quarter ended September 30, 1998.
Total sales of the company's HIV protease inhibitor VIRACEPT(R) (nelfinavir
mesylate), were $133,870,000, including $107,187,000 in North American sales,
a 42% increase from the same period a year ago.  Prior year results for the
same period were a net income of $3,630,000, or $.11 per share, on total
revenues of $91,857,000.
    "VIRACEPT is now the most widely prescribed HIV protease inhibitor in the
United States and in certain major European markets," said Peter Johnson,
Agouron's president and chief executive officer.  "We estimate that
approximately 150,000 people are taking VIRACEPT on a worldwide basis."
    Agouron Pharmaceuticals, Inc. is an integrated pharmaceutical company
committed to the discovery, development, manufacturing, and marketing of
innovative therapeutic products engineered to inactivate proteins that play
key roles in cancer, AIDS, and other serious diseases.
For more information on Agouron, you may visit the Agouron Web Site at:
http://www.agouron.com
VIRACEPT(R) is a registered trademark of Agouron Pharmaceuticals, Inc.
    VIRACEPT is indicated for the treatment of HIV infection when
antiretroviral therapy is warranted.  This indication is based on analyses of
surrogate marker changes in patients who received VIRACEPT in combination with
nucleoside analogues or alone for up to 24 weeks.  At present, there are no
results from controlled trials evaluating the effect of therapy with VIRACEPT
on clinical progression of HIV infection, such as survival or the incidence of
opportunistic infections.
    The most commonly observed adverse event of moderate or greater severity
in clinical trials of VIRACEPT was diarrhea, which was generally controlled
with over-the-counter medications.  New onset or exacerbation of diabetes
mellitus and hyperglycemia, as well as increased bleeding in patients with
hemophilia types A and B, have been reported with protease inhibitors.

                     CONSOLIDATED STATEMENT OF INCOME (LOSS)
                     (In thousands, except per share amounts)

                                            Three Months Ended
                                               September 30,
                                          1998                1997
                                                (Unaudited)
    Revenues:
       Product sales                    $133,870            $79,502
       Contracts                           6,017             10,003
       License fees and royalties          5,050              2,352

                                         144,937             91,857

    Operating expenses:
       Cost of product sales              57,045             34,073
       Research and development           37,364             26,932
       Selling, general and
        administrative                    17,142             12,546
       Royalties                          25,893             13,376

                                         137,444             86,927

    Operating income                       7,493              4,930

    Other income (expense):
       Interest and other income           1,036              1,281
       Interest expense                    (423)              (161)

                                             613              1,120

    Income before income taxes             8,106              6,050

    Income tax provision                   1,216              2,420

    Net income                            $6,890             $3,630

    Earnings per share:
       Basic                                $.22               $.12
       Diluted                              $.21               $.11

    Shares used in calculation of:
       Basic                              31,127             29,964
       Diluted                            33,179             33,158

                            CONSOLIDATED BALANCE SHEET
                                  (In thousands)

                                      September 30,         June 30,
                                          1998                1998
                                      (Unaudited)          (Audited)
    Assets:
       Cash, cash equivalents
        and short-term investments       $61,940            $87,123
       Accounts receivable, net           51,755             51,341
       Inventories                       106,638            103,706
       Current deferred tax assets           564                564
       Other current assets                3,868              5,247
         Total current assets            224,765            247,981

       Property and equipment, net        45,670             47,212
       Deferred tax assets                64,999             64,644
       Purchased intangibles               3,350              3,500

                                        $338,784           $363,337

    Liabilities and stockholders' equity:
       Accounts payable and accrued
        liabilities                      $62,601            $79,749
       Deferred revenue and advances      21,191             23,563
       Current deferred tax liabilities    1,621              1,139
       Loan payable and current
        portion of long-term debt            819             15,802
         Total current liabilities        86,232            120,253

       Long-term debt, less
        current portion                    6,242              5,892
       Accrued rent                          938              1,023
       Stockholders' equity              245,372            236,169

                                        $338,784           $363,337

    Shares outstanding                    31,247             31,053


SOURCE Agouron Pharmaceuticals, Inc.




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    CONTACT:
    Donna Nichols, Vice President and Head of
    Corporate Communications of Agouron Pharmaceuticals, Inc.,
    619-622-3009