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Ventana Medical Systems, Inc. Reports 39% Increase in Third Quarter Revenues

                 104 Instrument Modules Placed in The Quarter

    TUCSON, Ariz., Oct. 22 /PRNewswire/ -- Ventana Medical Systems, Inc.
(Nasdaq: VMSI) today reported a 39% increase in sales for the quarter ended
September 30, 1998, compared to the same quarter last year.  During the
quarter, 104 instrument modules were placed.  The Company's sales and gross
profit growth were significant factors in the Company recording its eighth
consecutive quarterly profit, excluding one time litigation charges reported
in last year's second quarter.
    Net sales for the third quarter ended September 30, 1998 increased to
$11.1 million from $8.0 million for the same period in 1997.  Third quarter
net income was $1,137,000 or $.08 per diluted share compared to $113,000 or
$.01 per diluted share for the year ago quarter.
    "Three positive trends in our business fundamentals underlie our strong
third quarter results," commented Hank Pietraszek, president and chief
executive officer.  "Instrument placements remain strong as evidenced by our
42% increase in instrument sales.  In fact, we placed 104 IHC modules directly
with customers in the third quarter compared with 74 modules during the same
prior year period.  Further, our consumable usage per instrument remains
robust as evidenced by 37% growth versus prior year.  Finally, our gross
margins continue to strengthen, growing by 160 basis points from last year to
slightly above 70% in the September 30th quarter."  Pietraszek added, "Due to
the imminent shipment of special stains modules and the introduction of in
situ hybridization modules next year, we now refer to module placements rather
than system placements.  Each module is a revenue generating placement, and
each NexES system can have up to eight modules."
    Mr. Pietraszek went on to add "that the modest decline in revenues between
the second and third quarter was caused by the seasonality of the company's
European operations and the termination of its distribution arrangement with
DAKO."
    Pietraszek noted that "research and development spending growth of 104% in
the third quarter, as compared to the same prior year quarter, represented
spending on a strong new product pipeline including the recently launched
special stains instrument."
    Net sales for the nine-month period ended September 30, 1998 of
$33.0 million were up 47% from $22.4 million in the prior year comparable
period.  Net income for the nine months of 1998 was $3,250,000, as opposed to
a loss of $1,056,000 in the comparable prior year period and diluted earnings
per share for the nine months of 1998 were $.22 per share versus a loss of
$.08 per share in the prior year period.
    Safe Harbor Statement:  Statements in this press release which are not
strictly historical are "forward-looking" statements that are made pursuant to
the Safe Harbor provisions of the Private Securities Litigation Reform Act of
1995.  Forward-looking statements involve known and unknown risks, which may
cause the company's actual results in the future to differ materially from
expected results.  The risks and uncertainties that may affect the results of
the company's business are described in the company's specific filings with
the Securities and Exchange Commission.
    Ventana develops, manufactures and markets instrument/reagents systems
that automate tissue preparation and slide staining in histology laboratories
worldwide.  Ventana's systems are important tools used in the diagnosis and
treatment of cancer and infectious diseases.

                        VENTANA MEDICAL SYSTEMS, INC.
                    CONSOLIDATED STATEMENTS OF OPERATIONS
                     (in thousands except per share data)
                                 (Unaudited)

                                                 Three Months Ended:
                                                     September 30,
                                                 1998             1997
    Sales:
     Instruments                                 $3,047         $2,142
     Reagents and other                           8,061          5,872
         Total net sales                         11,108          8,014
    Cost of goods sold                            3,303          2,511
    Gross profit                                  7,805          5,503
    Operating expenses:
     Research and development                     1,435            702
     Selling, general and administrative          5,699          4,555
    Nonrecurring expenses                            --             --
    Amortization of intangibles                     128            128
    Income from operations                          543            118
    Other income                                    594             (5)
    Net income                                   $1,137           $113

    Basic earnings per share                       $.09           $.01
    Diluted earnings per share                     $.08           $.01

                        VENTANA MEDICAL SYSTEMS, INC.
                    CONSOLIDATED STATEMENTS OF OPERATIONS
                     (in thousands except per share data)
                                 (Unaudited)

                                                   Nine Months Ended:
                                                      September 30,
                                                 1998             1997
    Sales:
     Instruments                                $10,469         $6,032
     Reagents and other                          22,576         16,393
         Total net sales                         33,045         22,425
    Cost of goods sold                           10,233          7,992
    Gross profit                                 22,812         14,433
    Operating expenses:
     Research and development                     4,026          2,145
     Selling, general and administrative         16,220         11,563
    Nonrecurring expenses                            --          1,656
    Amortization of intangibles                     382            382
    Income from operations                        2,184         (1,313)
    Other income                                  1,066            257
    Net income                                   $3,250        $(1,056)

    Basic earnings (loss) per share                $.24          $(.08)
    Diluted earnings (loss) per share              $.22          $(.08)

                        VENTANA MEDICAL SYSTEMS, INC.
                          CONSOLIDATED BALANCE SHEET
                       (in thousands except share data)

                                             September 30,    December 31,
    ASSETS                                       1998            1997
                                              (Unaudited)        (Note)
    Current assets:
     Cash and cash equivalents                  $17,275        $18,902
     Accounts receivable                         11,581          8,047
     Inventories                                  8,157          5,134
     Other current assets                         3,073          2,109
    Total current assets                         40,086         34,192
    Property and equipment, net                   6,901          6,105
    Intangibles, net                              7,637          8,055
    Total assets                                $54,624        $48,352

       LIABILITIES AND STOCKHOLDERS' EQUITY

    Current liabilities
     Accounts payable                            $2,374         $2,584
     Other current liabilities                    3,224          2,894
    Total current liabilities                     5,598          5,478
    Long term debt                                1,826            471
    Stockholders' equity:
     Common stock - $0.001 par value; 50,000,000
      shares authorized; 13,368,526 and 13,247,226
      shares issued and outstanding at September 30,
      1998 and December 31, 1997, respectively       13             13
     Additional Paid-In Capital                  78,148         76,313
     Accumulated deficit                        (30,532)       (33,782)
     Cumulative foreign currency
      translation adjustment                       (429)          (141)
    Total stockholders' equity                   47,200         42,403
    Total liabilities and stockholders' equity  $54,624        $48,352

    Note:  The consolidated balance sheet at December 31, 1997 has been
derived from the audited financial statements at that date but does not
include all of the information and footnotes required by generally accepted
accounting principles for complete financial statements.

                        VENTANA MEDICAL SYSTEMS, INC.
                    CONSOLIDATED STATEMENTS OF CASH FLOWS
                                (in thousands)
                                 (Unaudited)


                                                   Nine Months Ended:
                                                      September 30,
                                                 1998           1997
    Operating activities:
    Net income                                   $3,250        $(1,056)
    Adjustments to reconcile net income (loss)
     to cash used in operating activities:
     Depreciation and amortization                1,990          1,505
     Changes in operating assets and
      liabilities, net                           (6,301)        (2,258)
    Net cash provided by (used in)
     operating activities                        (1,061)        (1,809)

    Investing activities:
    Purchase of property and equipment, net      (2,113)        (3,142)
    Purchase of intangible assets                    --            (43)
    Net cash used in investing activities        (2,113)        (3,185)

    Financing activities:
    Issuance (repayment) of debt (including
     amounts from related parties) and stock      1,835        (10,321)
    Net proceeds from public offering                --         26,138
    Net cash provided by financing activities     1,835         15,817

    Effect of exchange rate change on cash         (288)            47
    Net increase in cash and cash equivalents    (1,627)        10,870

    Cash and cash equivalents,
     beginning of period                         18,902         11,067
    Cash and cash equivalents, end of period    $17,275        $21,937


SOURCE Ventana Medical Systems, Inc.




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CONTACT:
Henry T. Pietraszek, President and Chief
Executive Officer of Ventana Medical Systems, Inc., 520-887-2155;
or Bill Murphy, General Inquiries, or Kathy Brunson, Analyst
Contact, or Darcy Bretz, Media Inquiries, 312-266-7800, all of
the Financial Relations Board for Ventana Medical Systems, Inc.
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Inc. via facsimile at no additional cost, simply dial
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