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Biogen Idec Reports Third Quarter 2004 Results

   Biogen Idec Inc. logo. (PRNewsFoto)

CAMBRIDGE AND SAN DIEGO, MA, CA USA
    CAMBRIDGE, Mass., Oct. 27 /PRNewswire-FirstCall/ -- Biogen Idec Inc.
(Nasdaq: BIIB), the world's third largest biotech company with leading
products and capabilities in oncology and immunology, today reported its third
quarter 2004 results.
    (Logo: http://www.newscom.com/cgi-bin/prnh/20031112/LAW121LOGO )

    Third Quarter Highlights
    * Revenues were $543 million vs. prior year (adjusted pro forma of $477
      million, an increase of 14%), driven primarily by AVONEX(R) (Interferon
      beta-1a) sales up 16% (adjusted pro forma) to $346 million and
      RITUXAN(R) (rituximab) co-promotion profits up 19% to $160 million.
    * On a GAAP basis, earnings per share (EPS) were $0.10; excluding merger-
      related accounting impacts and other non-operating charges, adjusted
      pro forma (non-GAAP) EPS were $0.37.
    * Elan and Biogen Idec announced that the companies have submitted an
      application to the European Medicines Agency for approval of
      ANTEGREN(R) (natalizumab) as a treatment for Crohn's disease.
    * Sunesis Pharmaceuticals, Inc. and Biogen Idec announced a collaboration
      to discover and develop small molecule cancer therapeutics targeting
      kinases, a family of cell signaling enzymes that play a major role in
      the progression of cancer.
    * ImmunoGen, Inc. and Biogen Idec announced that Biogen Idec has licensed
      exclusive rights to develop and commercialize anti-cancer therapeutics
      that comprise an antibody developed by Biogen Idec to an undisclosed
      tumor cell target and ImmunoGen's proprietary Tumor-Activated Prodrug
      (TAP) technology.
    * Biogen Idec announced its Board of Directors has authorized the
      repurchase of up to 20 million shares of its common stock.

    "Since we completed our merger transaction approximately one year ago,
Biogen Idec has delivered on its promise," said James Mullen, Biogen Idec's
Chief Executive Officer.  "I applaud the organization for the smooth and rapid
integration.  We've hit our major financial goals, the pipeline has advanced
both through in-house efforts and business development deals, and we are on
the verge of launching our next product."

    Financial Performance
    On an adjusted non-GAAP basis, Biogen Idec reported net income was $132
million in the third quarter of 2004 (Q3 2003: $123 million).  Adjusted non-
GAAP EPS was $0.37 for the third quarter of 2004 (Q3 2003: $0.35).
    Adjusted non-GAAP EPS and net income for the third quarter of 2004
excludes merger-related accounting impacts, such as amortization of
intangibles, impairment of intangibles, inventory step up, and other merger-
related charges, and other non-operating charges.  Adjusted pro forma non-GAAP
EPS and net income for the third quarter of 2003 include revenue and expenses
from the former Biogen, Inc. from July 1 to September 30, 2003 but excludes
other non-operating charges of the former Biogen, Inc. and IDEC

Pharmaceuticals Corporation.  These adjustments, expenses, and non-operating
charges are itemized on the attached reconciliation tables.
    On a reported basis, calculated in accordance with U.S. generally accepted
accounting principles (GAAP), Biogen Idec reported net income of $37 million
(or EPS of $0.10) in the third quarter of 2004.  The difference between
adjusted non-GAAP net income and EPS and GAAP net income and EPS in the third
quarter was primarily due to $112 million of non-cash merger-related
accounting impacts and $13 million write-down of certain investments.

    Revenue Performance
    Third quarter revenues of AVONEX, Biogen Idec's therapy for patients with
relapsing forms of multiple sclerosis, increased 16% to $346 million (adjusted
pro forma Q3 2003: $298 million).  U.S. sales were  $224 million (adjusted pro
forma Q3 2003: $204 million).  International sales were $122 million (adjusted
pro forma Q3 2003: $94 million); in local currency, sales grew 21%.
    Revenues for the third quarter of 2004 included $160 million from Biogen
Idec's joint business arrangement with Genentech, Inc. related to RITUXAN, a
treatment for certain B-cell non-Hodgkin's lymphomas that Biogen Idec co-
promotes in the U.S. with Genentech (Q3 2003: $134 million).  All U.S. sales
of RITUXAN are recognized by Genentech, and Biogen Idec records its share of
the pretax co-promotion profits on a quarterly basis.  U.S. net sales of
RITUXAN in the third quarter of 2004, as recorded by Genentech, were $393
million (Q3 2003: $354 million).
    Revenues of ZEVALIN(R) (ibritumomab tiuxetan), Biogen Idec's
radioimmunotherapeutic agent, were $5 million in the third quarter of 2004 (Q3
2003: $4 million).
    Revenues of AMEVIVE(R) (alefacept), Biogen Idec's treatment for moderate-
to-severe psoriasis, were $8 million in the third quarter of 2004 (Q3 2003:
$12 million).
    Royalties were $24 million in the third quarter (adjusted pro forma Q3
2003: $29 million).

    Share Repurchase Program
    Biogen Idec announced that its Board of Directors has authorized the
repurchase of up to 20 million shares of its common stock.  The repurchased
stock will provide the Company with treasury shares for general corporate
purposes, such as stock to be issued under employee stock option and stock
purchase plans.  The share buyback will be largely funded through operating
cash flow and will be accretive to EPS.
    William Rastetter, Biogen Idec's Executive Chairman, said, "This share
repurchase plan underscores the belief of management and the Board of
Directors that our common stock represents an attractive investment for the
Company, based on our well-defined strategy and our prospects for future
growth.  Given our strong anticipated operating cash flow, we do not expect
this program to restrict our strategic flexibility."
    The Company currently has approximately 334 million shares of common stock
outstanding.

    Recent Highlights
    * Biogen Idec announced on October 13, 2004, that Health Canada has
      authorized AMEVIVE for sale in Canada.  AMEVIVE, the first biologic
      approved for psoriasis in Canada, will be marketed for the treatment of
      patients with moderate-to-severe chronic plaque psoriasis who are
      candidates for systemic therapy or phototherapy.
    * On October 6, 2004, ImmunoGen, Inc. and Biogen Idec announced that
      Biogen Idec licensed exclusive rights to develop and commercialize
      anti-cancer therapeutics that comprise an antibody developed by Biogen
      Idec to an undisclosed tumor cell target and ImmunoGen's proprietary
      Tumor-Activated Prodrug (TAP) technology.
    * On September 29, 2004, Elan and Biogen Idec announced that they
      submitted a Marketing Authorisation Application (MAA) to the European
      Medicines Agency for the approval of ANTEGREN as a treatment for
      Crohn's disease.  Additionally, the companies presented new 12-month
      data from the Phase III maintenance trial, ENACT-2 (Evaluation of
      Natalizumab As Continuous Therapy-2), at the United European
      Gastroenterology Week meeting in Prague, Czech Republic, and these data
      were included in the filing.
    * On September 7, 2004, Sunesis Pharmaceuticals, Inc. and Biogen Idec
      announced a collaboration to discover and develop small molecule cancer
      therapeutics targeting kinases, a family of cell signaling enzymes that
      play a major role in the progression of cancer.  The companies will
      apply Tethering(R), Sunesis' proprietary fragment-based drug discovery
      technology, in an effort to generate novel small molecule leads that
      inhibit oncology kinase targets.
    * On August 17, 2004, Biogen Idec and Elan announced that the companies
      have submitted an application for approval of ANTEGREN as a treatment
      for multiple sclerosis in Canada, based on one-year data from the
      ongoing Phase III trials.

    Conference Call and Webcast
    The Company's earnings conference call for the third quarter will be
broadcast via the internet at 5:00 p.m. ET on October 27, 2004, and will be
accessible through the investor relations section of Biogen Idec's homepage,
http://www.biogenidec.com.

    About Biogen Idec
    Biogen Idec creates new standards of care in oncology and immunology. As a
global leader in the development, manufacturing, and commercialization of
novel therapies, Biogen Idec transforms scientific discoveries into advances
in human healthcare. For product labeling, press releases and additional
information about the company, please visit http://www.biogenidec.com.

    Safe Harbor
    This press release contains forward-looking statements regarding expected
future financial results and plans for our development programs, including
ANTEGREN.
    These statements are based on the Company's current beliefs and
expectations.  A number of risks and uncertainties could cause actual results
to differ materially.  For example, financial results, including future
operating cash flow and overall prospects for growth, may be affected by a
number of factors, including any slowing of growth of the markets for AVONEX
and RITUXAN, any change in market acceptance of these products in key markets
worldwide, the extent to which the Company achieves market acceptance of its
other products, the impact of reimbursement and pricing decisions related to
the Company's products, the impact of competitive products on the Company's
products, any material decreases in sales by licensees of products on which
the Company receives royalties, the impact of litigation, any unanticipated
increase in expenses, in-licensing and product opportunities, increase in
costs related to development and commercialization of new products, including
ANTEGREN, and any material issues, delays or failures related to the
manufacturing or supply of the Company's products.
    Our long-term growth will depend on the successful development and
commercialization of new products such as ANTEGREN.  Drug development involves
a high degree of risk.  For example, our plans to launch ANTEGREN as a
treatment for MS could be negatively affected if unexpected concerns arise
from additional data or analysis, if regulatory authorities require additional
information or further studies, or if we were to encounter other unexpected
hurdles.
    For more detailed information on the risks and uncertainties associated
with these forward looking statements and the Company's other activities see
the periodic reports filed by the Company with the Securities and Exchange
Commission.  The Company does not undertake any obligation to publicly update
any forward-looking statements, whether as a result of new information, future
events, or otherwise.

    Media Contact:
     Amy Ryan
     Associate Director, Public Affairs
     Biogen Idec
     Tel: (617) 914-6524

    Investment Community Contact:
     Elizabeth Woo
     Senior Director, Investor Relations
     Biogen Idec
     Tel: (617) 679-2812


    TABLE 1
                 Financial Results For The Third Quarter of 2004
             Condensed Consolidated Statements Of Income - GAAP Basis
                     (in thousands, except per share amounts)


                                      Three Months Ended   Nine Months Ended
                                        September 30,        September 30,
                                        2004     2003       2004       2003
    REVENUES

    Product                           $359,692   $4,427  $1,095,415   $15,069

    Revenue from unconsolidated joint
     business                          159,507  133,960     444,619   363,236

    Royalties                           23,860      -        73,371       -

    Corporate partner                      217      143      10,377     1,032

    Total Revenues                     543,276  138,530   1,623,782   379,337

    COST AND EXPENSES

    Cost of product and royalty
     revenues                           64,460      639     470,955     5,282

    Research and development           168,889   39,333     498,219   121,384

    Selling, general and
     administrative                    132,040   27,157     401,887    74,985

    Amortization of acquired
     intangible assets                 107,054      -       267,222       -

    Total Cost and Expenses            472,443   67,129   1,638,283   201,651

    Income (Loss) from Operations       70,833   71,401     (14,501)  177,686

    Other income (expense), net         (1,573)   1,986      16,566     8,549

    INCOME BEFORE INCOME TAXES          69,260   73,387       2,065   186,235

    Income taxes                        32,492   27,887       5,668    70,769

    NET INCOME (LOSS)                  $36,768  $45,500     $(3,603) $115,466

    BASIC EARNINGS (LOSS) PER SHARE      $0.11    $0.29      $(0.01)    $0.73

    DILUTED EARNINGS (LOSS) PER SHARE    $0.10    $0.26      $(0.01)    $0.67

    SHARES USED IN CALCULATING:

    BASIC EARNINGS (LOSS) PER SHARE    334,777  155,498     335,165   155,117

    DILUTED EARNINGS (LOSS) PER SHARE  355,232  184,838     335,165   178,877


    TABLE 2
                                         Condensed Consolidated Balance Sheets
                                                  (dollars in thousands)


                                              Sep. 30, 2004     Dec. 31, 2003

       Assets:
       Current assets

       Cash, cash equivalents and
        securities available-for-sale             $445,880          $835,959

       Accounts receivable, net                    237,572           198,524

       Inventory                                   246,369           496,349

       Other current assets                        334,414           307,832

       Total current assets                      1,264,235         1,838,664

       Long-term securities available-
        for-sale                                 1,672,126         1,502,327

       Property and equipment, net               1,415,689         1,252,783

       Intangible assets, net                    3,370,624         3,638,812

       Goodwill                                  1,151,105         1,151,066

       Other                                       146,819           120,293

       Total assets                             $9,020,598        $9,503,945


       Liabilities and shareholders'
        equity

       Current liabilities                        $428,601          $404,825

       Long-term deferred tax liability            985,672         1,108,318

       Non-current liabilities                     896,063           937,474

       Shareholders' equity                      6,710,262         7,053,328

       Total liabilities and
        shareholders' equity                    $9,020,598        $9,503,945




    TABLE 3

    Condensed Consolidated Statements of Operations and Reconciliation of
    GAAP Earnings to Adjusted Pro-Forma Non-GAAP Earnings
    (In millions, except per share data)

              The non-GAAP financial measures presented below are utilized
              by Biogen Idec management to gain an understanding of the
              comparative financial performance of the Company.
              Management believes that the non-GAAP financial measures are
              useful because they exclude those non-operational or unusual
              activities or transactions that are not necessarily
              relevant to understanding the trends of the Company or the
              prospects of future performance.   Numbers may not foot due
              to rounding.

                                            Three Months Ended
                                            September 30, 2004

                                                               Adjusted
                                      GAAP     Adjustments     Non-GAAP


    Revenues

    Product                          $359.7          -          $359.7
    Revenue from unconsolidated
     joint business                   159.5          -           159.5
    Royalties                          23.9          -            23.9
    Corporate partner                   0.2          -             0.2
    Total revenues                    543.3          -           543.3

    Cost and Expenses
    Cost of product and royalty
     revenues                          64.5         (3.3) (A)     61.2
    Research and development          168.9         (0.1) (B)    168.8
    Selling, general and
     administrative                   132.0         (1.7) (B)    130.3
    Amortization of acquired
     intangible assets                107.1       (107.1) (C)      -
    Total costs and expenses          472.4       (112.2)        360.3

    Income from operations             70.8        112.2         183.0

    Other income (expense), net        (1.6)        12.7  (D)     11.2

    Income before income taxes         69.3        124.9         194.2

    Provision for income taxes         32.5         29.6  (E)     62.1

    Net income                        $36.8        $95.3        $132.0

              Numerator:
                   Net Income         $36.8                     $132.0
                   Net Income
                    allocable to
                    participating
                    securities        ($0.1)(H)                  ($0.2)(H)
                   Net Income used
                    in calculating
                    basic eps         $36.7                     $131.8
                   Net Adjustment
                    for interest
                    expense            $0.5 (I)                   $2.0
                   Net Income used
                    in calculating
                    diluted eps       $37.2                     $133.8


    Shares used  in calculation of
     earnings per share:

              Denominator:
                   Weighted average
                    number of common
                    shares
                    outstanding       334.8                      334.8
                   Effect of
                    dilutive
                    securities:
                    stock options,
                    convertible
                    promissory notes   20.5 (I)                   29.1
                   Dilutive
                    potential common
                    shares            355.2                      363.9

    Earnings per share:
    Basic                             $0.11                      $0.39
    Diluted                           $0.10                      $0.37


                                     column 1      column 2     column 3 =
                                                                columns 1+2

              (A) Represents the non-cash expense related to valuing the
                  inventory acquired from former Biogen, Inc. at fair value.
              (B) Represents external, incremental consulting, integration
                  costs, severance,  and restructuring charges related to the
                  merger.
              (C) Represents the on-going, non-cash amortization and
                  impairment of acquired intangible assets related to the
                  merger with former Biogen, Inc.
              (D) Represents $12.7M for the write-down of certain
                  investments.
              (E) Represents the tax effect of the above adjustments.
              (F) Represents the elimination of Biogen Idec contract
                  revenue and expense of $3.1M.
              (G) Represents former Biogen, Inc. operating revenue and
                  expenses for the period Jul-Sep of 2003 prior to the merger,
                  net of intercompany transactions.
              (H) Due to adoption of EITF 03-06 which requires allocation
                  of income to certain holders of equity & debt instruments.
              (I) Adjustment for certain interest expense and convertible
                  securities were included in the period as they were
                  dilutive.


    TABLE 3

    Condensed Consolidated Statements of Operations and Reconciliation of
    GAAP Earnings to Adjusted Pro-Forma Non-GAAP Earnings
    (In millions, except per share data)

              The non-GAAP financial measures presented below are utilized
              by Biogen Idec management to gain an understanding of the
              comparative financial performance of the Company.
              Management believes that the non-GAAP financial measures are
              useful because they exclude those non-operational or unusual
              activities or transactions that are not necessarily
              relevant to understanding the trends of the Company or the
              prospects of future performance.   Numbers may not foot due
              to rounding.

                                            Three Months Ended
                                            September 30, 2003
                                                              Adjusted
                                                             Pro Forma
                                     GAAP     Adjustments     Non-GAAP


    Revenues

    Product                           $4.4       $310.1  (G)   $314.5
    Revenue from unconsolidated
     joint business                  134.0          -           134.0
    Royalties                          -           28.6  (G)     28.6
    Corporate partner                  0.1          -             0.1
    Total revenues                   138.5        338.7         477.2

    Cost and Expenses
    Cost of product and royalty
     revenues                          0.6         54.3  (G)     54.9
    Research and development          39.3         87.9  (F),
                                                         (G)    127.2
    Selling, general and
     administrative                   27.2         96.1  (G)    123.3
    Amortization of acquired
     intangible assets                 -            -             -
    Total costs and expenses          67.1        238.3         305.4

    Income from operations            71.4        100.4         171.8

    Other income (expense), net        2.0          6.9  (G)      8.9

    Income before income taxes        73.4        107.3         180.6

    Provision for income taxes        27.9         30.0  (G)     57.8

    Net income                       $45.5        $77.4        $122.8

              Numerator:
                   Net Income        $45.5                     $122.8
                   Net Income
                    allocable to
                    participating
                    securities       ($0.6)(H)                  ($0.8)(H)
                   Net Income used
                    in calculating
                    basic eps        $44.9                     $122.0
                   Net Adjustment
                    for interest
                    expense           $2.9                       $2.9
                   Net Income used
                    in calculating
                    diluted eps      $47.8                     $124.9


    Shares used  in calculation of
     earnings per share:

              Denominator:
                   Weighted average
                    number of common
                    shares
                    outstanding      155.5                      327.4
                   Effect of
                    dilutive
                    securities:
                    stock options,
                    convertible
                    promissory notes  29.3                       30.3
                   Dilutive
                    potential common
                    shares           184.8                      357.8

    Earnings per share:
    Basic                            $0.29                      $0.37
    Diluted                          $0.26                      $0.35


                                     column 4      column 5     column 6 =
                                                                columns 4+5



              (A) Represents the non-cash expense related to valuing the
                  inventory acquired from former Biogen, Inc. at fair value.
              (B) Represents external, incremental consulting, integration
                  costs, severance,  and restructuring charges related to the
                  merger.
              (C) Represents the on-going, non-cash amortization and
                  impairment of acquired intangible assets related to the
                  merger with former Biogen, Inc.
              (D) Represents $12.7M for the write-down of certain
                  investments.
              (E) Represents the tax effect of the above adjustments.
              (F) Represents the elimination of Biogen Idec contract
                  revenue and expense of $3.1M.
              (G) Represents former Biogen, Inc. operating revenue and
                  expenses for the period Jul-Sep of 2003 prior to the merger,
                  net of intercompany transactions.
              (H) Due to adoption of EITF 03-06 which requires allocation
                  of income to certain holders of equity & debt instruments.
              (I) Adjustment for certain interest expense and convertible
                  securities were included in the period as they were
                  dilutive.


    TABLE 4

    Condensed Consolidated Statements of Operations and Reconciliation of
    GAAP Earnings to Adjusted Pro-Forma Non-GAAP Earnings
    (In millions, except per share data)

              The non-GAAP financial measures presented below are
              utilized by Biogen Idec management to gain an understanding
              of the comparative financial performance of the Company.
              Management believes that the non-GAAP financial measures
              are useful because they exclude those non-operational or
              unusual activities or transactions that are not necessarily
              relevant to understanding the trends of the Company or the
              prospects of future performance.   Numbers may not foot due
              to rounding.

                                             Nine Months Ended
                                             September 30, 2004

                                                                Adjusted
                                      GAAP      Adjustments     Non-GAAP


    Revenues

    Product                         $1,095.4          -         $1,095.4
    Revenue from unconsolidated
     joint business                    444.6          -            444.6
    Royalties                           73.4          -             73.4
    Corporate partner                   10.4          -             10.4
    Total revenues                   1,623.8          -          1,623.8

    Cost and Expenses
    Cost of product and royalty
     revenues                          471.0       (291.1) (A)     179.9
    Research and development           498.2         (3.0) (B)     495.2
    Selling, general and
     administrative                    401.9         (6.7) (B)     395.2
    Amortization of acquired
     intangible assets                 267.2       (267.2) (C)       -
    Total costs and expenses         1,638.3       (568.0)       1,070.3

    Income (loss) from operations      (14.5)       568.0          553.5

    Other income, net                   16.6         12.7  (D)      29.3

    Income before income taxes           2.1        580.7          582.8

    Provision for income taxes           5.7        180.8  (E)     186.5

    Net income (loss)                  ($3.6)      $399.9         $396.3

              Numerator:
                   Net Income
                    (Loss)             ($3.6)                     $396.3
                   Net Income
                    allocable to
                    participating
                    securities           -   (I)                   ($0.6)(I)
                   Net Income
                    (Loss) used in
                    calculating
                    basic eps          ($3.6)                     $395.8
                   Net Adjustment
                    for interest
                    expense              -   (J)                    $6.8
                   Net Income
                    (Loss) used in
                    calculating
                    diluted eps        ($3.6)                     $402.6


    Shares used in calculation of
     earnings (loss) per share:

              Denominator:
                   Weighted average
                    number of
                    common shares
                    outstanding        335.2                       335.2
                   Effect of
                    dilutive
                    securities:
                    stock options,
                    convertible
                    promissory
                     notes               -   (J)                    31.6
                   Dilutive
                    potential
                    common shares      335.2                       366.8

    Earnings (Loss) per share:
    Basic                             ($0.01)                      $1.18
    Diluted                           ($0.01)                      $1.10


                                     column 1      column 2     column 3 =
                                                                columns 1+2



              (A) Represents the non-cash expense related to valuing the
                  inventory acquired from former Biogen, Inc. at fair value.
              (B) Represents external, incremental consulting,
                  integration costs, severance,  and restructuring charges
                  related to the merger.
              (C) Represents the on-going, non-cash amortization and
                  impairment of acquired intangible assets related to the
                  merger with former Biogen, Inc.
              (D) Represents $12.7M for the write-down of certain
                  investments.
              (E) Represents the tax effect of the above adjustments.
              (F) Represents the elimination of Biogen Idec contract
                  revenue and expense of $6.3M.
              (G) Represents former Biogen, Inc. operating revenue and
                  expenses for the period Jan-Sep of 2003 prior to the
                  merger, net of intercompany transactions.
              (H) Represents former IDEC one-time adjustment of $20M
                  related to a signing payment for the Genentech new anti-
                  CD20 antibody development collaboration.
              (I) Due to adoption of EITF 03-06 which requires
                  allocation of income to certain holders of equity & debt
                  instruments.
              (J) Adjustment for certain interest expense and convertible
                  securities were included in the period as they were
                  dilutive.


    TABLE 4

    Condensed Consolidated Statements of Operations and Reconciliation of
    GAAP Earnings to Adjusted Pro-Forma Non-GAAP Earnings
    (In millions, except per share data)

              The non-GAAP financial measures presented below are
              utilized by Biogen Idec management to gain an understanding
              of the comparative financial performance of the Company.
              Management believes that the non-GAAP financial measures
              are useful because they exclude those non-operational or
              unusual activities or transactions that are not necessarily
              relevant to understanding the trends of the Company or the
              prospects of future performance.   Numbers may not foot due
              to rounding.

                                            Nine Months Ended
                                            September 30, 2003
                                                              Adjusted
                                                              Pro Forma
                                     GAAP     Adjustments     Non-GAAP


    Revenues

    Product                          $15.1       $881.4  (G)    $896.5
    Revenue from unconsolidated
     joint business                  363.2          -            363.2
    Royalties                          -          100.4  (G)     100.4
    Corporate partner                  1.0          -              1.0
    Total revenues                   379.3        981.9        1,361.2

    Cost and Expenses
    Cost of product and royalty
     revenues                          5.3        146.2  (G)     151.5
    Research and development         121.4        253.2  (F),
                                                         (G),
                                                         (H)     374.6
    Selling, general and
     administrative                   75.0        296.4  (G)     371.4
    Amortization of acquired
     intangible assets                 -            -              -
    Total costs and expenses         201.7        695.8          897.5

    Income (loss) from operations    177.7        286.1          463.7

    Other income, net                  8.5         28.2  (G)      36.7

    Income before income taxes       186.2        314.2          500.4

    Provision for income taxes        70.8         89.3  (G)     160.1

    Net income (loss)               $115.5       $224.8         $340.3

              Numerator:
                   Net Income
                    (Loss)          $115.5                      $340.3
                   Net Income
                    allocable to
                    participating
                    securities       ($1.6)(I)                   ($2.2)(I)
                   Net Income
                    (Loss) used in
                    calculating
                    basic eps       $113.9                      $338.2
                   Net Adjustment
                    for interest
                    expense           $5.5                        $7.2
                   Net Income
                    (Loss) used in
                    calculating
                    diluted eps     $119.4                      $345.3


    Shares used  in calculation of
     earnings (loss) per share:

              Denominator:
                   Weighted average
                    number of
                    common shares
                    outstanding      155.1                       326.4
                   Effect of
                    dilutive
                    securities:
                    stock options,
                    convertible
                    promissory
                     notes            23.8                        30.5
                   Dilutive
                    potential
                    common shares    178.9                       356.9

    Earnings (Loss) per share:
    Basic                            $0.73                       $1.04
    Diluted                          $0.67                       $0.97


                                    column 4       column 5     column 6 =
                                                                columns 4+5

              (A) Represents the non-cash expense related to valuing the
                  inventory acquired from former Biogen, Inc. at fair value.
              (B) Represents external, incremental consulting,
                  integration costs, severance,  and restructuring charges
                  related to the merger.
              (C) Represents the on-going, non-cash amortization and
                  impairment of acquired intangible assets related to the
                  merger with former Biogen, Inc.
              (D) Represents $12.7M for the write-down of certain
                  investments.
              (E) Represents the tax effect of the above adjustments.
              (F) Represents the elimination of Biogen Idec contract
                  revenue and expense of $6.3M.
              (G) Represents former Biogen, Inc. operating revenue and
                  expenses for the period Jan-Sep of 2003 prior to the
                  merger, net of intercompany transactions.
              (H) Represents former IDEC one-time adjustment of $20M
                  related to a signing payment for the Genentech new anti-
                  CD20 antibody development collaboration.
              (I) Due to adoption of EITF 03-06 which requires
                  allocation of income to certain holders of equity & debt
                  instruments.
              (J) Adjustment for certain interest expense and convertible
                  securities were included in the period as they were
                  dilutive.



     TABLE 5

                                 Biogen Idec Inc
                     Product Revenues for Third Quarter 2004
                                  (in thousands)

    The non-GAAP financial measures presented below are utilized by Biogen
    Idec management to gain an understanding of the comparative financial
    performance of the Company. Management believes that the non-GAAP
    financial measures are useful because they exclude those non-operational
    or unusual activities or transactions that are not necessarily relevant to
    understanding the trends of the Company or the prospects of future
    performance.  Numbers may not foot due to rounding.


                                                       Three Months Ended
                                                          September 30,
                                        2004                 2003

                                                           Biogen
                                                  U.S.     Revenue   Pro Forma
                                    U.S. GAAP     GAAP       Pre-     Combined
                                     Revenue    Revenue     merger(a)  Revenue
    PRODUCT REVENUES


       Avonex(R)                    $346,248        $-    $297,728    $297,728

       Amevive(R)                      8,222         -      12,381      12,381

       Zevalin(R)                      5,222      4,427         -        4,427


    Total Product Revenues          $359,692     $4,427   $310,109    $314,536



                                                       Nine Months Ended
                                                          September 30,
                                        2004                 2003
                                                           Biogen
                                                  U.S.     Revenue   Pro Forma
                                    U.S. GAAP     GAAP       Pre-     Combined
                                     Revenue    Revenue    merger(a)  Revenue
    PRODUCT REVENUES


       Avonex(R)                   $1,047,482       $-    $858,361    $858,361

       Amevive(R)                      33,325        -      23,074      23,074

       Zevalin(R)                      14,608    15,069          -      15,069


    Total Product Revenues         $1,095,415   $15,069   $881,435    $896,504


       (a)  Represents former Biogen, Inc. revenue that is not included in
            GAAP revenues.


SOURCE Biogen Idec Inc.




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