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aaiPharma Announces Exclusive License Agreement With Salix Pharmaceuticals for Azasan(R)

    WILMINGTON, N.C., Nov. 4 /PRNewswire-FirstCall/ -- aaiPharma Inc.
(Nasdaq: AAII) announced today that it has granted Salix Pharmaceuticals an
exclusive license to market the 25 mg, 75 mg and 100 mg strengths of Azasan(R)
(azathioprine).  The agreement calls for Salix to make an up-front payment to
aaiPharma as well as on-going royalty on net sales.  aaiPharma will continue
to manufacture the products and supply all of Salix's needs for the products.
    "Azasan(R) is a strategic fit with our current portfolio and sales focus
in the marketplace," stated Ms. Carolyn J. Logan, President and CEO of Salix
Pharmaceuticals, Ltd.  "The innovative 25 mg, 75 mg and 100 mg dosage forms
developed by aaiPharma offer physicians and patients greater dosing
flexibility for patients taking 100 mg or more of therapy each day."
    Dr. Philip S. Tabbiner, President and CEO of aaiPharma added, "Salix is
the ideal company to help us fully leverage the clinical value of Azasan(R).
This agreement allows us to maximize the benefits of our development work with
azathioprine while continuing to focus our field sales organization on our
growing pain management portfolio, especially the launch of Darvocet
A500(TM)."

    About aaiPharma
    aaiPharma Inc. is a leading, science-based specialty pharmaceutical
company with corporate headquarters in Wilmington, North Carolina.  With more
than 23 years of drug development expertise and a proven sales and marketing
track record, the Company is focused on acquiring, improving and marketing
well-known, branded medicines in pain management, gastroenterology and
critical care.  In addition to its branded product portfolio and robust
pipeline, aaiPharma continues to offer comprehensive drug development services
to the pharmaceutical, biotechnology, generic and device industries through
its services division, AAI Development Services. For more information, please
visit aaiPharma's website at http://www.aaipharma.com.

    About Salix Pharmaceuticals
    Salix Pharmaceuticals, Ltd., headquartered in Raleigh, North Carolina,
develops and markets prescription pharmaceutical products for the treatment of
gastrointestinal diseases. Salix's strategy is to in-license late-stage or
marketed proprietary therapeutic drugs; complete any required development and
regulatory submission of these products; and market them through the Company's
84-member gastroenterology specialty sales marketing team. Salix trades on the
Nasdaq National Market under the ticker symbol "SLXP." For more information
please visit our web site at http://www.salix.com.

    Forward Looking Statements for aaiPharma
    Information in this press release contains certain "forward-looking
statements" within the meaning of Section 27A of the Securities Act of 1933
and Section 21E of the Securities and Exchange Act of 1934, including the
statements by Dr. Tabbiner and Ms. Logan.  The "forward-looking statements"
herein involve risks and uncertainties that could cause actual results to
differ materially, including, without limitation, risks and uncertainties
pertaining aaiPharma's ability to successfully develop, improve, obtain timely
regulatory approval for, and profitably sell pharmaceutical products
(including Darvocet A500(TM)); the effect of possible future acquisitions,
dispositions and other strategic transactions involving the Company; and the
commercial success of the Company's contemplated products and services.
Additional factors that may cause the actual results to differ materially are
discussed in aaiPharma's recent filings with the Securities and Exchange
Commission, including, but not limited to, its Annual Report on Form 10-K
filed on March 28, 2003, including its Exhibit 99.1 and other exhibits; its
Forms 10-Q filed on May 15, 2003 and August 14, 2003 (including its Exhibit
99.1); its Form 8-Ks; and its other periodic filings.

    Azasan(R) is a registered trademark, and Darvocet A500(TM) is a trademark,
owned by aaiPharma Inc.


SOURCE aaiPharma Inc.




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    CONTACT:
    media, Andrea L. Johnston, Vice President,
    Corporate Communications, +1-910-254-7340, or investors, James B.
    Sloan, Jr., Senior Vice President, Corporate Finance,
    +1-910-254-7690, both of aaiPharma Inc.