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Cardinal Health Reports First Quarter Results

                - Revenue increases 5 percent to $22 billion
             - Operating earnings up 9 percent to $490 million
 - Diluted earnings per share from continuing operations rise 15 percent to
                              $0.82 per share
 - Non-GAAP diluted EPS from continuing operations increases 15 percent to
                              $0.86 per share
 - Full year EPS guidance reaffirmed, outlook revised for Healthcare Supply
                   Chain Services-Pharmaceutical segment

    DUBLIN, Ohio, Nov. 5 /PRNewswire-FirstCall/ -- Cardinal Health, a
global provider of products and services that improve the safety and
productivity of health care, today reported a 15 percent increase in
earnings per share during its first quarter, led by strong profit growth in
its clinical and medical products businesses and ongoing programs to
repurchase shares and streamline operations.
    For the quarter ended Sept. 30, revenue increased 5 percent to $22
billion, operating earnings increased 9 percent to $490 million and
earnings per share from continuing operations rose 15 percent to $0.82, or
$0.86(1) on a non-GAAP basis.
    "Our first quarter results were solid and led by very strong
performance in our Clinical and Medical Products sector, which now accounts
for 30 percent of segment profits," said R. Kerry Clark, chief executive
officer of Cardinal Health.
    Cardinal Health also reaffirmed its annual earnings-per-share guidance,
while lowering the profit outlook for its Healthcare Supply Chain Services-
Pharmaceutical segment. The company continues to expect a strong second
half of the fiscal year, led by continued growth in clinical and medical
products and a significant increase in generic product introductions.
    "We are disappointed with the performance in our Healthcare Supply
Chain Services-Pharmaceutical segment, but have a positive outlook for the
second half of the fiscal year for the company," Clark said. "Our Clinical
and Medical Products sector will be a key growth driver, and we also expect
to benefit from new generic pharmaceutical launches and improvements in
operational performance."
    Cardinal Health separately announced that Mark W. Parrish, who led the
Healthcare Supply Chain Services sector, is leaving the company.  Chief
Financial Officer Jeffrey W. Henderson will assume the additional role of
interim CEO of Healthcare Supply Chain Services until a permanent successor is
named.



    Q1 FY08 Summary
                                  Q1 FY08         Q1 FY07             Y/Y

    Revenue                     $22 billion     $21 billion            5%

    Operating Earnings         $490 million    $451 million            9%
    Non-GAAP Operating
     Earnings(2)               $512 million    $475 million            8%

    Earnings from
     Continuing
     Operations                $303 million    $291 million            4%
    Non-GAAP Earnings
     from Continuing
     Operations(3)             $318 million    $309 million            3%

    Diluted EPS from
     Continuing Operations            $0.82           $0.71           15%
    Non-GAAP Diluted EPS
     from Continuing
     Operations                       $0.86           $0.75           15%



    First quarter segment results:

    Healthcare Supply Chain Services Sector

    -- Revenue for the Healthcare Supply Chain Services-Pharmaceutical segment
       grew 4 percent during the quarter to $19.2 billion, with sales to non-
       bulk customers declining 2 percent to $10.3 billion and sales to bulk
       customers increasing 11 percent to $8.9 billion.  Segment profit
       increased 6 percent to $305 million, benefiting from the $14 million
       adjustment of a vendor related reserve, and partially dampened by sales
       mix, generic market conditions, nuclear pharmacy pricing pressure and a
       moderation in the sale of prescription drugs.

    -- Revenue for the Healthcare Supply Chain Services-Medical segment
       increased 6 percent to $1.9 billion, with improving demand in new and
       existing hospital, laboratory and ambulatory customers.  Segment profit
       declined 10 percent to $58 million due primarily to a previously
       disclosed change in corporate cost allocation that reduced profit by 9
       percentage points.  The company continues to expect a return to
       profitable growth in the segment later this fiscal year and made
       progress against that goal during the quarter with continued
       improvements in customer service operations and strength in its
       hospital supply business.

    Clinical and Medical Products Sector

    -- Revenue for the Clinical Technologies and Services segment increased 9
       percent to $649 million from continued strong demand for Alaris(R) and
       Pyxis(R) products.  Segment profit increased 91 percent to $98 million
       with good sales momentum from the fourth quarter in dispensing products
       and a favorable mix of product revenue.  The segment also benefited
       from a favorable comparison to the prior-year period where a $13.5
       million charge was taken for the recall of Alaris SE products.

    -- Revenue for the Medical Products and Technologies segment increased 47
       percent to $623 million, led by strong sales of new products and the
       addition of VIASYS Healthcare, acquired by Cardinal Health in June.
       Segment profit grew 24 percent to $57 million and benefited from the
       integration of VIASYS, which remains ahead of the company's schedule.

    Additional first quarter and recent highlights include:

    -- Repurchasing approximately $600 million of Cardinal Health shares
       during the quarter and announcing an additional two-year, $2 billion
       repurchase authorization in August.
    -- Introducing several new products, including Esteem Micro surgical
       gloves made from a proprietary, latex-free material; new Presource(R)
       surgical kits for cosmetic procedures and to help prevent central line
       infections; the LTV 1150 ventilator for home use; and CareFusion(TM)
       Transfusion Verification with Rapid Infusion for use in hospital
       emergency rooms.
    -- Signing an exclusive marketing agreement with Sentry Data Systems to
       offer eligible hospitals and health care facilities technology services
       that help cost-efficiently extend care to the uninsured and
       underinsured under the federal 340B Drug Pricing program.
    -- Launching the $1 million, Cardinal Health Patient Safety Challenge
       Grant program to support initiatives to improve safety in U.S.
       hospitals.  More than 700 hospitals responded to the challenge and are
       competing for 30 to 40 grants.
    -- Breaking ground on a $50 million expansion of the company's
       headquarters in Ohio to consolidate its Healthcare Supply Chain
       Services businesses.
    Outlook
    Cardinal Health reiterated its fiscal 2008 guidance range of $3.95 to
$4.15 for non-GAAP diluted EPS from continuing operations. In addition, the
company revised the outlook for its Healthcare Supply Chain Services-
Pharmaceutical segment, which is now expected to grow profit during the
year below its long term goal of 7 to 10 percent growth. Cardinal Health
previously said profit growth for this segment was expected to be in line
with the long term range.
    Conference Call
    Cardinal Health will host a conference call and webcast at 8:30 a.m.
EST to discuss the results. To access the call and corresponding slide
presentation, go to the Investor page at http://www.cardinalhealth.com. The
conference call may also be accessed by calling 617-213-4857, passcode
21392080. An audio replay will be available until 11:30 p.m. EST on Nov. 7
at 617-801-6888, passcode 50524989. A transcript and audio replay will also
be available at http://www.cardinalhealth.com.
    About Cardinal Health
    Headquartered in Dublin, Ohio, Cardinal Health, Inc. (NYSE: CAH) is an
$87 billion, global company serving the health care industry with products
and services that help hospitals, physician offices and pharmacies reduce
costs, improve safety, productivity and profitability, and deliver better
care to patients. With a focus on making supply chains more efficient,
reducing hospital-acquired infections and breaking the cycle of harmful
medication errors, Cardinal Health develops market leading technologies,
including Alaris(R) IV pumps, Pyxis(R) automated dispensing systems,
MedMined(TM) infection surveillance services and the CareFusion(TM) patient
identification system. The company also manufactures medical and surgical
products and is one of the largest distributors of pharmaceuticals and
medical supplies worldwide. Ranked No. 19 on the Fortune 500 and No. 1 in
its sector on Fortune's ranking of Most Admired firms, Cardinal Health
employs more than 40,000 people on five continents. More information about
the company may be found at http://www.cardinalhealth.com.
    (1) Non-GAAP diluted EPS from continuing operations:  Non-GAAP earnings
        from continuing operations divided by diluted weighted average shares
        outstanding.

    (2) Non-GAAP operating earnings:  Operating earnings excluding special
        items and impairment charges and other.

    (3) Non-GAAP earnings from continuing operations:  Earnings from
        continuing operations excluding special items and impairment charges
        and other, both net of tax.
    A reconciliation of the differences between these non-GAAP financial
measures and their most directly comparable GAAP financial measures is
provided in the attached tables and at http://www.cardinalhealth.com.
    This news release contains forward-looking statements addressing
expectations, prospects, estimates and other matters that are dependent
upon future events or developments. These matters are subject to risks and
uncertainties that could cause actual results to differ materially from
those projected, anticipated or implied. The most significant of these
uncertainties are described in Cardinal Health's Form 10-K, Form 10-Q and
Form 8-K reports (including all amendments to those reports) and exhibits
to those reports, and include (but are not limited to) the following:
competitive pressures in its various lines of business; the loss of one or
more key customer or supplier relationships or changes to the terms of
those relationships; uncertainties relating to timing of generic
introductions and the frequency or rate of branded pharmaceutical price
appreciation or generic pharmaceutical price deflation; changes in the
distribution patterns or reimbursement rates for health-care products
and/or services; the results, consequences, effects or timing of any
inquiry or investigation by any regulatory authority or any legal and
administrative proceedings; successful integration of Cardinal Health and
VIASYS Healthcare and the ability to achieve synergies from the
acquisition; and general economic and market conditions. This news release
reflects management's views as of Nov. 5, 2007. Except to the extent
required by applicable law, Cardinal Health undertakes no obligation to
update or revise any forward-looking statement.
                      CARDINAL HEALTH, INC. AND SUBSIDIARIES
                 CONSOLIDATED STATEMENTS OF EARNINGS (UNAUDITED)

    (in millions, except per Common Share          First Quarter
     amounts)                                   2008          2007    % Change

    Revenue                                  $21,973.4     $20,937.5       5%
    Cost of products sold                     20,631.2      19,737.0       5%
    Gross margin                              $1,342.2      $1,200.5      12%

    Selling, general and administrative
     expenses                                    830.1         725.5      14%
    Impairment charges and other                  (0.2)          1.7      N.M.

    Special items:
     Restructuring charges                        14.8          11.8      N.M.
     Acquisition integration charges               5.4           1.9      N.M.
     Litigation and Other                          2.3           8.4      N.M.
    Operating earnings                          $489.8        $451.2       9%

    Interest expense and other                    42.9          37.8      13%
    Earnings before income taxes and
     discontinued operations                    $446.9        $413.4       8%

    Provision for income taxes                   143.7         122.0      18%
    Earnings from continuing operations         $303.2        $291.4       4%

    Loss from discontinued operations
     (net of tax (expense) / benefit of
     $(2.0) and $19.8 for the first quarter
     of fiscal 2008 and 2007, respectively)       (1.4)        (20.7)     N.M.

    Net earnings                                $301.8        $270.7      11%

    Basic Earnings (Loss) per Common
     Share:
    Continuing operations                        $0.83         $0.72      15%
    Discontinued operations                          -         (0.05)     N.M.
     Net basic earnings per Common Share         $0.83         $0.67      24%

    Diluted Earnings (Loss) per Common
     Share:
    Continuing operations                        $0.82         $0.71      15%
    Discontinued operations                        -           (0.05)     N.M.
     Net diluted earnings per Common Share       $0.82         $0.66      24%

    Weighted Average Number of Shares
     Outstanding:
    Basic                                        363.0         404.5
    Diluted                                      370.2         413.0



                     CARDINAL HEALTH, INC. AND SUBSIDIARIES
                     CONSOLIDATED BALANCE SHEETS (UNAUDITED)

                                                September 30,       June 30,
    (in millions)                                   2007              2007

    Assets
    Cash and equivalents                          $1,289.6          $1,308.8
    Short-term investments available for
     sale                                                -             132.0
    Trade receivables, net                         4,904.7           4,714.4
    Current portion of net investment in
     sales-type leases                               369.1             354.8
    Inventories                                    7,150.8           7,383.2
    Prepaid expenses and other                       619.0             651.3
      Total current assets                       $14,333.2         $14,544.5

    Property and equipment, net                    1,683.1           1,647.0
    Net investment in sales-type leases,
     less current portion                            830.5             820.7
    Goodwill and other intangibles, net            5,822.8           5,860.9
    Other assets                                     328.5             280.7
      Total assets                               $22,998.1         $23,153.8


    Liabilities and Shareholders' Equity
    Current portion of long-term
     obligations and other short-term
     borrowings                                     $386.8             $16.0
    Accounts payable                               9,099.0           9,162.2
    Other accrued liabilities                      1,623.0           2,247.3
    Liabilities from businesses held for
     sale and discontinued operations                  5.2              34.2
      Total current liabilities                  $11,114.0         $11,459.7

    Long-term obligations, less current
     portion and other short-term borrowings       3,347.5           3,457.3
    Deferred income taxes and other
     liabilities                                   1,468.4             859.9
      Total shareholders' equity                   7,068.2           7,376.9
      Total liabilities and shareholders'
       equity                                    $22,998.1         $23,153.8



                      CARDINAL HEALTH, INC. AND SUBSIDIARIES
                 CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED)

                                                          First Quarter
     (in millions)                                   2008               2007

     Cash Flows From Operating Activities:
     Net earnings                                   $301.8             $270.7
     Loss from discontinued operations                 1.4               20.7
       Earnings from continuing operations          $303.2             $291.4
     Adjustments to reconcile earnings
      from continuing operations to net cash
      provided by operating activities:
       Depreciation and amortization                  94.9               78.4
       Asset impairments                              (0.2)               1.7
       Equity compensation                            26.1               37.4
       Provision for bad debts                         5.0                5.4
     Change in operating assets and
      liabilities, net of effects from
      acquisitions:
       (Increase) / decrease in trade
        receivables                                 (191.9)             107.0
       Decrease in inventories                       232.4              119.8
       Increase in net investment in
        sales-type leases                            (24.1)             (20.9)
       Decrease in accounts payable                  (63.2)            (131.5)
       Other accrued liabilities and
       operating items, net                           57.0              181.8
         Net cash provided by operating
          activities - continuing operations        $439.2             $670.5
         Net cash (used in) / provided by
          operating activities - discontinued
          operations                                 (30.4)              16.1
     Net cash provided by operating activities      $408.8             $686.6

     Cash Flows From Investing Activities:
     Acquisition of subsidiaries, net of
      divestitures and cash acquired                $(88.1)            $(64.5)
     Proceeds from sale of property and
      equipment                                        2.5                3.6
     Additions to property and equipment             (91.5)             (68.7)
     Sale of investment securities
      available for sale, net                        131.9               41.9
       Net cash used investing activities
        - continuing operations                     $(45.2)            $(87.7)
       Net cash provided by investing activities
        - discontinued operations                        -                3.6
     Net cash used in investing activities          $(45.2)            $(84.1)

     Cash Flows From Financing Activities:
     Net change in commercial paper and
      short-term borrowings                         $232.0             $105.4
     Reduction of long-term obligations              (13.0)             (27.8)
     Proceeds from long-term obligations,
      net of issuance costs                            0.1                1.7
     Proceeds from issuance of Common Shares         105.5               57.3
     Tax benefits from exercises of
      stock options                                   11.6               12.5
     Dividends on Common Shares                      (44.3)             (37.0)
     Purchase of treasury shares                    (674.7)            (445.3)
       Net cash used in financing activities
        - continuing operations                    $(382.8)           $(333.2)
       Net cash used in financing activities
        - discontinued operations                        -              (12.5)
     Net cash used in financing activities         $(382.8)           $(345.7)

     Net (decrease) / increase in cash
      and equivalents                                (19.2)             256.8

     Cash and equivalents at beginning of
      period                                      $1,308.8           $1,187.3

     Cash and equivalents at end of period        $1,289.6           $1,444.1



                     CARDINAL HEALTH, INC. AND SUBSIDIARIES
                                BUSINESS ANALYSIS

                                  TOTAL COMPANY

                                                                   Non-GAAP
                                               First Quarter     First Quarter
      (in millions)                           2008      2007      2008   2007

      Revenue
      Amount                               $21,973   $20,938
      Growth Rate                                5%       11%

      Operating Earnings
      Amount                                  $490      $451      $512   $475
      Growth Rate                                9%       23%        8%    23%

      Earnings from Continuing Operations
      Amount                                  $303      $291      $318   $309
      Growth Rate                                4%       24%        3%    24%


    Refer to the GAAP / Non-GAAP Reconciliation for Non-GAAP calculations.



                      CARDINAL HEALTH, INC. AND SUBSIDIARIES
                             SEGMENT BUSINESS ANALYSIS

        HEALTHCARE SUPPLY CHAIN SERVICES      CLINICAL AND MEDICAL PRODUCTS


                        First Quarter                          First Quarter
     (in millions)     2008     2007  (in millions)           2008     2007

     PHARMACEUTICAL                      CLINICAL TECHNOLOGIES AND SERVICES

     Revenue                             Revenue
     Amount          $19,221  $18,533    Amount                $649     $594
     Growth Rate           4%      12%   Growth Rate              9%       3%
     Mix                  86%      87%   Mix                      3%       3%

     Segment Profit (1)                  Segment Profit (1)
     Amount             $305     $289    Amount                 $98      $51
     Growth Rate           6%      28%   Growth Rate             91%     (10)%
     Mix                  59%      64%   Mix                     19%      12%
     Segment Profit                      Segment Profit
      Margin            1.59%    1.56%    Margin              15.14%    8.66%

     MEDICAL                             MEDICAL PRODUCTS AND TECHNOLOGIES

     Revenue                             Revenue
     Amount           $1,921   $1,806    Amount                $623     $424
     Growth Rate          6%        2%   Growth Rate             47%      11%
     Mix                  8%        8%   Mix                      3%       2%

     Segment Profit (1)                  Segment Profit (1)
     Amount              $58      $64    Amount                 $57      $46
     Growth Rate         (10)%     (1)%  Growth Rate             24%      36%
     Mix                  11%      14%   Mix                     11%      10%
     Segment Profit                      Segment Profit
      Margin            2.99%    3.55%    Margin               9.13%   10.86%

    (1) Refer to definitions for an explanation of segment profit.



                      CARDINAL HEALTH, INC. AND SUBSIDIARIES
                            ASSET MANAGEMENT ANALYSIS

                                                           First Quarter
                                                      2008              2007

     Receivable Days                                  22.2              16.9
     Days Inventory on Hand                             28                30

     Debt to Total Capital                              35%               26%
     Net Debt to Capital                                26%               11%

     Return on Equity                                 16.7%             12.8%
     Non-GAAP Return on Equity                        17.5%             13.6%

     Return on Invested Capital                       6.57%             5.14%
     Non-GAAP Return on Invested Capital              7.50%             5.93%

     Effective Tax Rate from Continuing
      Operations                                      32.2%             29.5%
     Non-GAAP Effective Tax Rate from
      Continuing Operations                           32.3%             29.4%

    Refer to the GAAP / Non-GAAP Reconciliation for Non-GAAP calculations.



                     CARDINAL HEALTH, INC. AND SUBSIDIARIES
                            SCHEDULE OF NOTABLE ITEMS

     (in millions, except per Common                      First Quarter
      Share amounts)                                  2008              2007


     Special Items
     Restructuring charges                          $(14.8)           $(11.8)
     Acquisition integration charges                  (5.4)             (1.9)
     Litigation and other                             (2.3)             (8.4)
       Total special items                          $(22.5)           $(22.1)
       Tax benefit                                     7.7               5.8
          Special items, net of tax                 $(14.8)           $(16.3)

     Decrease to diluted EPS from
      continuing operations                         $(0.04)           $(0.04)


     Impairment Charges and Other
     Impairment charges and other                     $0.2             $(1.7)
       Tax (expense) / benefit                        (0.1)              0.6
       Net impairment charges and other,
        net of tax                                    $0.1             $(1.1)

       Decrease to diluted EPS from
        continuing operations                           $-                $-

     Weighted Average Number of Diluted
      Shares Outstanding                             370.2             413.0



                       CARDINAL HEALTH, INC. AND SUBSIDIARIES
                           GAAP / NON-GAAP RECONCILIATION

                                                  First Quarter 2008

                                                          Impairment
      (in millions, except per Common            Special  Charges and
      Share amounts)                       GAAP   Items      Other    Non-GAAP


      Operating Earnings
      Amount                               $490      $23        -        $512
      Growth Rate                             9%                            8%

      Provision for Income Taxes           $144       $8        -        $151

      Earnings from Continuing Operations
      Amount                               $303      $15        -        $318
      Growth Rate                             4%                            3%

      Diluted EPS from Continuing
       Operations
      Amount                              $0.82    $0.04        -       $0.86
      Growth Rate                            15%                           15%



                                                  First Quarter 2007
                                                          Impairment
                                                 Special  Charges and
                                           GAAP   Items      Other    Non-GAAP


      Operating Earnings
      Amount                               $451      $22       $2        $475
      Growth Rate                            23%                           23%

      Provision for Income Taxes           $122       $6       $1        $128

      Earnings from Continuing Operations
      Amount                               $291      $16       $1        $309
      Growth Rate                            24%                           24%

      Diluted EPS from Continuing
       Operations
      Amount                              $0.71    $0.04        -       $0.75

    The sum of the components may not equal the total due to rounding



                     CARDINAL HEALTH, INC. AND SUBSIDIARIES
                         GAAP / NON-GAAP RECONCILIATION

                                                           First Quarter
    (in millions)                                     2008              2007

    GAAP Return on Equity                             16.7%             12.8%

    Non-GAAP Return on Equity
    Net earnings                                    $301.8            $270.7
    Special items, net of tax, in
     continuing operations                            14.8              16.3
    Special items, net of tax, in
     discontinued operations                             -               1.4
      Adjusted net earnings                         $316.6            $288.4

      Annualized                                  $1,266.4          $1,153.6

      Divided by average shareholders'
       equity (1)                                 $7,222.6          $8,455.9

    Non-GAAP return on equity                         17.5%             13.6%



                                                           First Quarter
    (in millions)                                     2008              2007


    GAAP Return on Invested Capital                   6.57%             5.14%

    Non-GAAP Return on Invested Capital
    Net earnings                                    $301.8            $270.7
    Special items, net of tax, in
     continuing operations                            14.8              16.3
    Special items, net of tax, in
     discontinued operations                            -                1.4
    Interest expense and other, net of tax            27.5              23.6
      Adjusted net earnings                         $344.1            $312.0

    Annualized                                    $1,376.4          $1,248.0

    Divided by average total invested
     capital (2)                                 $18,365.9         $21,050.9

    Non-GAAP return on invested capital               7.50%             5.93%


    (1) The average shareholders' equity shown above is calculated using the
        average of the prior years' fourth quarter and the current quarter.

    (2) The average total invested capital shown above is calculated using the
        average of the prior years' quarter and the current quarter. Total
        invested capital is calculated as the sum of the current portion of
        long-term obligations and other short-term borrowings, long-term
        obligations, current portion of long-term obligations and other
        short-term borrowings in discontinued operations, long-term
        obligations in discontinued operations, total shareholders' equity and
        unrecorded goodwill. Unrecorded goodwill is $7.5 billion and
        $9.7 billion, respectively, for the September 30, 2007 and 2006
        calculations. Current portion of long-term obligations and other
        short-term borrowings in discontinued operations, and long-term
        obligations in discontinued operations were $59.2 million and $46.6
        million at June 30, 2006 and September 30, 2006, respectively.



                     CARDINAL HEALTH, INC. AND SUBSIDIARIES
                         GAAP / NON-GAAP RECONCILIATION

                                                           First Quarter
    (in millions)                                     2008              2007

    GAAP Effective Tax Rate from Continuing
     Operations                                       32.2%             29.5%

    Non-GAAP Effective Tax Rate from
     Continuing Operations
    Earnings before income taxes and
     discontinued operations                        $446.9            $413.4
    Special items                                     22.5              22.1
      Adjusted earnings before income
       taxes and discontinued operations            $469.4            $435.5

    Provision for income taxes                      $143.7            $122.0
    Special items tax benefit                          7.7               5.8
      Adjusted provision for income taxes           $151.4            $127.8

    Non-GAAP effective tax rate from
     continuing operations                            32.3%             29.4%



                                                           First Quarter
                                                      2008              2007

    Debt to Total Capital                               35%               26%

    Net Debt to Capital
    Current portion of long-term
     obligations and other short-term
     borrowings                                     $386.8            $280.1
    Long-term obligations, less current
     portion and other short-term
     borrowings                                    3,347.5           2,616.0
      Debt                                        $3,734.3          $2,896.1
    Cash and equivalents                          (1,289.6)         (1,444.1)
    Short-term investments available for sale            -            (456.5)
      Net debt                                    $2,444.7            $995.5
    Total shareholders' equity                    $7,068.2          $8,421.1
    Capital                                       $9,512.9          $9,416.6
      Net debt to capital                               26%               11%


    Forward-Looking Non-GAAP Financial Measures
    The Company presents non-GAAP operating earnings, non-GAAP earnings from
    continuing operations, non-GAAP return on equity and non-GAAP effective
    tax rate from continuing operations (and presentations derived from these
    financial measures) on a forward-looking basis.  The most directly
    comparable forward-looking GAAP measures are operating earnings, earnings
    from continuing operations, return on equity and effective tax rate from
    continuing operations.  The Company is unable to provide a quantitative
    reconciliation of these forward-looking non-GAAP measures to the most
    comparable forward-looking GAAP measures because the Company cannot
    reliably forecast special items and impairment charges and other, which
    are difficult to predict and estimate and are primarily dependent on
    future events.  Please note that the unavailable reconciling items could
    significantly impact the Company's future financial results.



                    CARDINAL HEALTH, INC. AND SUBSIDIARIES
                                 DEFINITIONS

    GAAP
    Debt:  long-term obligations plus short-term borrowings

    Debt to Total Capital:  debt divided by (debt plus total shareholders'
    equity)

    Diluted EPS from Continuing Operations:  earnings from continuing
    operations divided by diluted weighted average shares outstanding

    Effective Tax Rate from Continuing Operations:  provision for income
    taxes divided by earnings before income taxes and discontinued operations

    Operating Cash Flow:  net cash provided by / (used in) operating
    activities from continuing operations

    Segment Profit:  segment revenue minus (segment cost of products sold and
    segment selling, general and administrative expenses)

    Segment Profit Margin:  segment profit divided by revenue

    Segment Profit Mix:  segment profit divided by total segment profit for
    all operating segments

    Return on Equity:  annualized net earnings divided by average
    shareholders' equity

    Return on Invested Capital:  annualized net earnings divided by (average
    total shareholders' equity plus debt plus unrecorded goodwill)

    Revenue Mix:  segment revenue divided by total revenue for all segments


    NON-GAAP
    Economic Profit:  segment net operating earnings, after-tax minus
    (tangible capital multiplied by weighted average cost of capital);
    Tangible Capital is the quarterly average calculated as total assets
    allocated to the segment less (total liabilities allocated to the segment,
    goodwill and intangibles, cash and equivalents and short term investments
    available for sale)

    Economic Profit Margin:  economic profit divided by revenue

    Net Debt to Capital:  net debt divided by (net debt plus total
    shareholders' equity)

    Net Debt:  debt minus (cash and equivalents and short-term investments
    available for sale)

    Non-GAAP Diluted EPS from Continuing Operations:  non-GAAP earnings from
    continuing operations divided by diluted weighted average shares
    outstanding

    Non-GAAP Diluted EPS from Continuing Operations Growth Rate:  (current
    period non-GAAP diluted EPS from continuing operations minus prior period
    non-GAAP diluted EPS from continuing operations) divided by prior period
    non-GAAP diluted EPS from continuing operations

    Non-GAAP Earnings from Continuing Operations:  earnings from continuing
    operations excluding special items and impairment charges and other, both
    net of tax

    Non-GAAP Earnings from Continuing Operations Growth Rate:  (current
    period non-GAAP earnings from continuing operations minus prior period
    non-GAAP earnings from continuing operations) divided by prior period
    non-GAAP earnings from continuing operations

    Non-GAAP Effective Tax Rate from Continuing Operations:  (provision for
    income taxes adjusted for special items) divided by earnings before income
    taxes and discontinued operations adjusted for special items)

    Non-GAAP Operating Earnings:  operating earnings excluding special items
    and impairment charges and other

    Non-GAAP Operating Earnings Growth Rate:  (current period non-GAAP
    operating earnings minus prior period non-GAAP operating earnings) divided
    by prior period non-GAAP operating earnings

    Non-GAAP Return on Equity:  (annualized current period net earnings plus
    special items minus special items tax benefit) divided by average
    shareholders' equity

    Non-GAAP Return on Invested Capital:  (annualized net earnings plus
    special items minus special items tax benefit plus interest expense and
    other, net of tax) divided by (average total shareholders' equity plus
    debt plus unrecorded goodwill)



                                  CARDINAL HEALTH, INC. AND SUBSIDIARIES
                                      GAAP / NON-GAAP RECONCILIATION

    (in millions)

    HEALTHCARE SUPPLY CHAIN SERVICES        First Quarter Fiscal 2008
    Pharmaceutical                   July       August   September      Total


    Economic Profit Margin
    Segment profit                                                     $305.4
    Effective tax rate from
     continuing operations                                               35.9%
    Net operating earnings, after-tax
    (NOPAT)                                                            $195.6

    Total assets                   $11,591.6  $11,719.5  $11,574.7
    Less:  assets from
     discontinued operations              -          -          -
    Less:  accounts payable          7,350.3    7,948.1    8,344.0
    Less:  other accrued
     liabilities                     1,211.8    1,173.2    1,130.7
    Less:  liabilities from
     businesses held for sale             -          -          -
    Less:  deferred income taxes
     and other liabilities              88.8       86.7       35.0
    Less:  goodwill and other
     intangibles, net                1,351.2    1,344.9    1,345.2
    Less:  cash and equivalents         65.4       51.4       38.3
    Less:  short-term investments
     available for sale                   -          -          -
    Tangible capital                $1,524.1   $1,115.2     $681.5   $1,106.9

    Multiplied by weighted average
     cost of capital                                                      2.3%

    Capital charge                                                      $25.5

    Economic profit                                                    $170.1

    Revenue                                                         $19,220.8

    Economic profit margin                                               0.88%



    (in millions)

    HEALTHCARE SUPPLY CHAIN SERVICES         First Quarter Fiscal 2007
    Pharmaceutical                   July       August   September      Total


    Economic Profit Margin
    Segment profit                                                     $288.7
    Effective tax rate from
     continuing operations                                               35.1%
    Net operating earnings, after-tax
     (NOPAT)                                                           $187.5

    Total assets                   $11,549.8  $12,206.9  $11,620.0
    Less:  assets from
     discontinued operations           107.5      109.4          -
    Less:  accounts payable          7,488.3    8,027.1    8,101.0
    Less:  other accrued
     liabilities                     1,069.5    1,088.6    1,016.3
    Less:  liabilities from
     businesses held for sale              -          -          -
    Less:  deferred income taxes
     and other liabilities              82.1       82.1       71.0
    Less:  goodwill and other
     intangibles, net                1,354.5    1,361.8    1,332.4
    Less:  cash and equivalents         42.2       57.4       75.0
    Less:  short-term investments
     available for sale                    -          -          -
    Tangible capital                $1,405.7   $1,480.5   $1,024.3   $1,303.5

    Multiplied by weighted average
     cost of capital                                                      2.3%

    Capital charge                                                      $30.0

    Economic profit                                                    $157.5

    Revenue                                                         $18,532.8

    Economic profit margin                                               0.85%

    (1) Tangible Capital is a quarterly average calculated as total assets
        allocated to the segment less (total liabilities allocated to the
        segment, goodwill and intangibles, cash and equivalents and short term
        investments available for sale)

    (2) The sum of the components may not equal the total due to rounding

    (3) Healthcare Supply Chain Services - Pharmaceutical Tangible Capital
        calculated for both current and prior fiscal year includes an
        allocation of payables previously held at Corporate to more accurately
        reflect the payable balance of the segment.



                                  CARDINAL HEALTH, INC. AND SUBSIDIARIES
                                      GAAP / NON-GAAP RECONCILIATION

    (in millions)

    HEALTHCARE SUPPLY CHAIN SERVICES            First Quarter Fiscal 2008
    Medical                              July     August  September     Total


    Economic Profit Margin
    Segment profit                                                      $57.5
    Effective tax rate from continuing
     operations                                                          29.3%
    Net operating earnings, after-tax
     (NOPAT)                                                            $40.6


    Total assets                       $2,481.8  $2,515.4  $2,552.6
    Less:  assets from discontinued
     operations                               -         -         -
    Less:  accounts payable               539.0     581.0     615.0
    Less:  other accrued liabilities       67.0      71.7      53.5
    Less:  liabilities from businesses
     held for sale                            -         -         -
    Less:  deferred income taxes and
     other liabilities                     54.6      55.4      61.3
    Less:  goodwill and other
     intangibles, net                     386.0     385.9     388.2
    Less:  cash and equivalents            24.4      25.7      21.6
    Less:  short-term investments
     available for sale                       -         -         -
    Tangible capital                   $1,410.8  $1,395.7  $1,413.0  $1,406.5

    Multiplied by weighted average
     cost of capital                                                      2.3%

    Capital charge                                                      $32.3

    Economic profit                                                      $8.3

    Revenue                                                          $1,920.7

    Economic profit margin                                               0.43%



    HEALTHCARE SUPPLY CHAIN SERVICES          First Quarter Fiscal 2007
    Medical                              July     August  September    Total

    Economic Profit Margin
    Segment profit                                                      $64.1
    Effective tax rate from continuing
     operations                                                          29.8%
    Net operating earnings, after-tax
     (NOPAT)                                                            $45.0

    Total assets                       $2,442.1  $2,437.6  $2,456.6
    Less:  assets from discontinued
     operations                               -         -         -
    Less:  accounts payable               534.8     478.7     510.4
    Less:  other accrued liabilities       71.1      78.1      49.4
    Less:  liabilities from businesses
     held for sale                            -         -         -
    Less:  deferred income taxes and
     other liabilities                     58.2      58.1      53.0
    Less:  goodwill and other
     intangibles, net                     378.8     377.8     377.7
    Less:  cash and equivalents             2.9       3.0       4.1
    Less:  short-term investments
     available for sale                       -         -         -
    Tangible capital                   $1,396.3  $1,441.9  $1,462.0  $1,433.4

    Multiplied by weighted average
     cost of capital                                                      2.3%

    Capital charge                                                      $33.0

    Economic profit                                                     $12.0

    Revenue                                                          $1,806.1

    Economic profit margin                                               0.66%

    (1) Tangible Capital is a quarterly average calculated as total assets
        allocated to the segment less (total liabilities allocated to the
        segment, goodwill and intangibles, cash and equivalents and short term
        investments available for sale)

    (2) The sum of the components may not equal the total due to rounding



                                  CARDINAL HEALTH, INC. AND SUBSIDIARIES
                                      GAAP / NON-GAAP RECONCILIATION

    (in millions)

    CLINICAL AND MEDICAL PRODUCTS              First Quarter Fiscal 2008
    Clinical Technologies and Services   July     August  September     Total

    Economic Profit Margin
    Segment profit                                                      $98.3
    Effective tax rate from continuing
     operations                                                          24.2%
    Net operating earnings, after-tax
     (NOPAT)                                                            $74.5

    Total assets                       $4,375.8  $4,301.6  $4,262.2
    Less:  assets from discontinued
     operations                               -         -         -
    Less:  accounts payable                82.0      63.3      62.3
    Less:  other accrued liabilities      575.9     592.2     250.3
    Less:  liabilities from businesses
     held for sale                            -         -         -
    Less:  deferred income taxes and
     other liabilities                    238.4     238.9     474.5
    Less:  goodwill and other
     intangibles, net                   2,171.8   2,206.2   2,180.4
    Less:  cash and equivalents           217.3     195.5     175.4
    Less:  short-term investments
     available for sale                       -         -         -
    Tangible capital                   $1,090.4  $1,005.5  $1,119.3  $1,071.7

    Multiplied by weighted average
     cost of capital                                                      2.3%

    Capital charge                                                      $24.6

    Economic profit                                                     $49.9

    Revenue                                                            $648.9

    Economic profit margin                                               7.69%



    CLINICAL AND MEDICAL PRODUCTS             First Quarter Fiscal 2007
    Clinical Technologies and Services     July     August  September    Total

    Economic Profit Margin
    Segment profit                                                      $51.5
    Effective tax rate from continuing
     operations                                                          29.2%
    Net operating earnings, after-tax
     (NOPAT)                                                            $36.5

    Total assets                         $3,916.6  $4,012.1  $3,880.1
    Less:  assets from discontinued
     operations                                 -         -         -
    Less:  accounts payable                  91.2      84.7      79.4
    Less:  other accrued liabilities        277.2     287.9     223.4
    Less:  liabilities from businesses
     held for sale                              -         -         -
    Less:  deferred income taxes and
     other liabilities                      577.6     577.0     475.1
    Less:  goodwill and other
     intangibles, net                     2,085.9   2,083.4   2,174.3
    Less:  cash and equivalents              66.2      60.1      82.6
    Less:  short-term investments
     available for sale                         -         -       0.3
    Tangible capital                       $818.5    $919.0    $845.0  $860.8

    Multiplied by weighted average cost
     of capital                                                           2.3%

    Capital charge                                                      $19.8

    Economic profit                                                     $16.7

    Revenue                                                            $594.5

    Economic profit margin                                               2.81%

    (1) Tangible Capital is a quarterly average calculated as total assets
        allocated to the segment less (total liabilities allocated to the
        segment, goodwill and intangibles, cash and equivalents and short term
        investments available for sale)

    (2) The sum of the components may not equal the total due to rounding



                                  CARDINAL HEALTH, INC. AND SUBSIDIARIES
                                      GAAP / NON-GAAP RECONCILIATION


    (in millions)

    CLINICAL AND MEDICAL PRODUCTS             First Quarter Fiscal 2008
    Medical Products and Technologies      July     August  September    Total

    Economic Profit Margin
    Segment profit                                                      $56.9
    Effective tax rate from continuing
     operations                                                          13.1%
    Net operating earnings, after-tax
     (NOPAT)                                                            $49.4

    Total assets                         $3,645.8  $3,661.3  $3,601.6
    Less:  assets from discontinued
     operations                                 -         -         -
    Less:  accounts payable                 123.8     127.9     123.1
    Less:  other accrued liabilities        270.7     266.5     207.0
    Less:  liabilities from businesses
     held for sale                              -         -         -
    Less:  deferred income taxes and
     other liabilities                      203.5     203.9     180.0
    Less:  goodwill and other
     intangibles, net                     1,945.4   1,952.2   1,910.5
    Less:  cash and equivalents             445.7     469.5     503.0
    Less:  short-term investments
     available for sale                         -         -         -
    Tangible capital                       $656.7    $641.3    $678.0  $658.7

    Multiplied by weighted average cost
     of capital                                                           2.3%

    Capital charge                                                      $15.2

    Economic profit                                                     $34.2

    Revenue                                                            $623.2

    Economic profit margin                                               5.49%



    CLINICAL AND MEDICAL PRODUCTS             First Quarter Fiscal 2007
    Medical Products and Technologies      July     August  September    Total

    Economic Profit Margin
    Segment profit                                                      $46.0
    Effective tax rate from continuing
     operations                                                           7.0%
    Net operating earnings, after-tax
     (NOPAT)                                                            $42.8

    Total assets                         $1,455.5  $1,453.1  $1,506.0
    Less:  assets from discontinued
     operations                                 -         -         -
    Less:  accounts payable                 107.3      88.5     118.3
    Less:  other accrued liabilities        119.3     124.7      89.1
    Less:  liabilities from businesses
     held for sale                              -         -         -
    Less:  deferred income taxes and
     other liabilities                       46.2      46.6      44.4
    Less:  goodwill and other
     intangibles, net                       454.8     453.7     453.4
    Less:  cash and equivalents             136.9     144.9     197.8
    Less:  short-term investments
     available for sale                         -         -         -
    Tangible capital                       $591.0    $594.7    $603.0  $596.2

    Multiplied by weighted average cost
     of capital                                                           2.3%

    Capital charge                                                      $13.7

    Economic profit                                                     $29.1

    Revenue                                                            $423.6

    Economic profit margin                                               6.87%

    (1) Tangible Capital is a quarterly average calculated as total assets
        allocated to the segment less (total liabilities allocated to the
        segment, goodwill and intangibles, cash and equivalents and short term
        investments available for sale)

    (2) The sum of the components may not equal the total due to rounding


SOURCE Cardinal Health, Inc.




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    CONTACT:
    Media, Jim Mazzola, +1-614-757-3690,
    jim.mazzola@cardinal.com, or Investors, Bob Reflogal,
    +1-614-757-7542, bob.reflogal@cardinal.com