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Icoria Announces 2005 Third Quarter Financial Results

          Losses Continue to Narrow as Company Focuses on Healthcare

    RESEARCH TRIANGLE PARK, N.C., Nov. 14 /PRNewswire-FirstCall/ --
Biotechnology company Icoria, Inc. (OTC Bulletin Board: ICOR.OB) today
announced that it further narrowed its losses as it continues its transition
from a life sciences company to a healthcare focused biotechnology company.
Icoria's quarterly net loss declined to $2.6 million, or $0.07 per share, from
more than $3.0 million or $0.08 per share the prior year. Year-to-date loss
was $0.12 cents per share, a significant improvement from the prior year's
loss of $0.29 per share.
    As expected, revenue for the quarter declined from $7.1 million the prior
year to $4.0 million, reflecting the loss of revenue related to the sale of
Icoria's agricultural genomics assets to Monsanto, as well as the conclusion
earlier in 2005 of Icoria's contract with Bayer CropScience.  For the first
nine months of 2005, total revenue was down 9 percent, from $18.3 million in
2004 to $16.7 million.  Icoria's healthcare revenue was $2.4 million in the
third quarter.
    As of September 30, Icoria reported unrestricted cash, cash equivalents
and short term investments in the amount of $6.1 million, down from
$8.7 million in the second quarter.  Icoria's accounts receivable had
decreased to $3.5 million from $4.6 million the prior quarter.
    "In the third quarter, Icoria continued to focus its business model on the
pursuit of those metabolomic and gene expression services that realize
immediate revenue while developing proprietary biomarkers that could
potentially generate revenue in the short- and mid-term," said Douglas Morton,
Interim CEO.  "However, the highlight of the quarter is the merger agreement
we signed with Clinical Data, Inc. whereby, subject to our shareholders'
approval, Clinical Data will acquire Icoria in an all-stock transaction later
this year.  We expect Icoria to continue to operate as a wholly-owned
subsidiary of Clinical Data after the transaction closes."

    Clinical Data Merger
    Under the agreement and assuming that the average closing price of
Clinical Data's common stock during the ten trading days before the merger
closes is $22.74 per share, Icoria shareholders will receive 0.01391 shares of
Clinical Data Common Stock for each share of Icoria Common Stock they own,
subject to adjustment as described in the agreement.  However, in no instance
will the aggregate purchase price in the merger be less than $10,000,000 or
more than $12,500,000.  Clinical Data and Icoria have filed a Registration
Statement on Form S-4, which encompasses a proxy statement and prospectus,
with the SEC in connection with the transaction.
    While Icoria's board has already approved the agreement, a shareholder
meeting to vote on the transaction is scheduled for Dec. 20.   On Nov. 10,
Icoria filed with the SEC and expects to mail to its stockholders a proxy
statement/prospectus in connection with the transaction.  The Registration
Statement and the proxy statement/prospectus contain important information
about Clinical Data, Icoria, the transaction, and related matters.  Investors

and existing security holders are urged to read the Registration Statement and
the proxy statement/prospectus carefully when they become available.
    Investors and existing security holders will be able to obtain free copies
of the Registration Statement and the proxy statement/prospectus and other
documents filed with the SEC by Clinical Data and Icoria through the investor
relations sections of the web sites of the respective companies or through the
EDGAR system available at the SEC web site at http://www.sec.gov or by contacting the
investor relations department of either company.
    More information on this transaction is available at http://www.icoria.com.  More
information on Clinical Data is available at http://www.clda.com.

    Quarterly Conference Call
    The company's management team will conduct a conference call and webcast
to discuss the third quarter results on Tuesday, November 15, at 8:30 a.m. ET.
Interested participants should call 1-800-231-9012 or, for those calling
internationally, 1-719-457-2617.  The conference call ID number is 2030345.
Icoria encourages participants to dial in ten minutes before the call
commences.
    The webcast can be accessed from Icoria's web site at
http://www.icoria.com by clicking on the Investor Relations link.  For those
unable to participate, replays of the call may be heard online at
http://www.icoria.com.  Supplemental information will also be available
online.

    About Icoria
    Icoria, Inc. is a biotechnology company focused on the discovery of novel,
multi-parameter biomarkers using its unique multi-platform approach.  Icoria
intends to use these future biomarkers internally to develop multi-analyte
diagnostics to define and grade pathology or disease state with a high level
of specificity and sensitivity, and use its technology to help collaborators
and customers develop better, safer drugs and diagnostics and to identify
targets, leads and drug/diagnostic combinations for liver injury, metabolic
disorders and cancer. Icoria's shares trade on the over the counter bulletin
board.

    This press release contains forward-looking statements including, but not
limited to, Icoria's acquisition by Clinical Data, Inc., the Company's
expectations for its healthcare based business model and its biomarker
discovery platform.  Such forward-looking statements are based on management's
current expectations and are subject to a number of risks, factors and
uncertainties that may cause actual results, events and performance to differ
materially from those referred to in the forward-looking statements.  These
risks, factors and uncertainties include, but are not limited to, Icoria's
ability to identify biomarkers, early stage of development, history of net
losses, technological and product development uncertainties, reliance on
research collaborations, uncertainty of additional funding and ability to
protect its patents and proprietary rights.  Certain of these and other risks
are identified in Icoria's 2005 Quarterly Reports on Form 10-Q for the periods
ended September 30, June 30, March 31, as amended, and its Annual Report on
Form 10-K for the year ended December 31, 2004, as filed with the Securities
and Exchange Commission.  The Company does not intend to update any of the
forward-looking statements after the date of this release to conform these
statements to actual results or to changes in our expectations, except as may
be required by law.


                                 ICORIA, INC.
                      CONDENSED STATEMENTS OF OPERATIONS
                                 (Unaudited)

                          Three Months Ended           Nine Months Ended
                             September 30,               September 30,
                          2005          2004           2005         2004

    Revenues:
    Revenues from
     healthcare
     customers
       Commercial and
        government
        contracts       $1,898,000    $2,977,000    $6,896,000    $5,885,000
       Government grant    502,000       322,000     1,423,000     1,189,000
    Total healthcare
     revenues            2,400,000     3,299,000     8,319,000     7,074,000

    Revenue from
     agriculture
     commercial
     contracts           1,553,000     3,821,000     8,387,000    11,188,000
    Total revenues       3,953,000     7,120,000    16,706,000    18,262,000

    Operating expenses:
    Research and
     development         4,345,000     7,524,000    17,167,000    20,555,000
    Selling, general
     and administrative  2,030,000     2,610,000     7,967,000     7,909,000

    Total operating
     expenses            6,375,000    10,134,000    25,134,000    28,464,000

    Gain on Monsanto
     transaction               ---           ---    (4,701,000)          ---

    Loss from
     operations         (2,422,000)   (3,014,000)   (3,727,000)  (10,202,000)

    Other interest
     income (expense),
     net                  (212,000)      (46,000)     (804,000)     (173,000)

    Net loss from
     continuing
     operations         (2,634,000)   (3,060,000)   (4,531,000)  (10,375,000)

    Discontinued
     operations              4,000         6,000         5,000        32,000

    Net loss
     attributable to
     common
     stockholders      $(2,630,000)  $(3,054,000)  $(4,526,000) $(10,343,000)

    Net loss per share
     - basic and
     diluted
    Loss from continuing
     operations             $(0.07)       $(0.08)       $(0.12)       $(0.29)

    Loss from
     discontinued
     operations                ---           ---           ---           ---

    Net loss per
     common share           $(0.07)       $(0.08)       $(0.12)       $(0.29)

    Weighted average
     common shares
     outstanding -
     basic and diluted  39,501,000    36,300,000    38,858,000    35,325,000



                                 Icoria, Inc.
                          2005 Third-Quarter Results
                         Condensed Balance Sheet Data

                                                September 30,     December 31,
                                                    2005              2004
                                                 (unaudited)
    Assets:
    Cash, cash equivalents, short-term
     investments                                   $6,072             $9,598
    Accounts Receivable                             3,463              1,816
    Other current assets                            1,062              1,600
                Total Current Assets               10,597            $13,014
    Property plant & equipment net                  7,084             14,516
    Other noncurrent assets                           759              1,740
    Total Assets                                  $18,440            $29,270

    Liabilities and Stockholders' Equity:
    Current liabilities                             8,006            $13,689
    Long-term obligations                           2,891              4,802
    Stockholders' equity                            7,543             10,779
    Total Liabilities and Stockholders' Equity    $18,440            $29,270



                                 Icoria, Inc.
        Supplemental Information Re: Increase/(Decrease) in Cash, Cash
    Equivalents, Short - Term and Long - Term Investments (See Note Below)
                                 (Unaudited)

                            Three Months Ended           Nine Months Ended
                               September 30                September 30
                            2005          2004           2005         2004
    Net cash used in
     operating
     activities         $(2,244,000)  $(2,277,000)   $(7,697,000) $(6,001,000)

    Net cash (used in)
     provided by
     investing activities,
     excluding purchases
     and maturities of
     short-term and
     long-term
     investments            (48,000)     (527,000)     5,161,000    1,294,000

    Net cash used in
     financing
     activities            (326,000)     (832,000)      (990,000)  (4,491,000)

    Net decrease in cash,
     cash equivalents,
     short-term
     investments and
     long-term
     investments         (2,618,000)   (3,636,000)    (3,526,000)  (9,198,000)

    Cash, cash
     equivalents,
     short-term
     investments and
     long-term
     investments,
     beginning of
     period               8,690,000    10,723,000      9,598,000   16,285,000

    Cash, cash
     equivalents,
     short-term
     investments and
     long-term
     investments, end
     of period           $6,072,000    $7,087,000     $6,072,000   $7,087,000


    Note 1:  The above presentation of the change in cash and investments is
not meant to be in accordance with generally accepted accounting principles
("GAAP") in the U.S.  GAAP requires the presentation of a statement of cash
flows only (i.e., excluding changes in short and long-term investments). In
order to fully assess the Company's liquidity position, management believes
that the cash flow measure presented above, which includes short-term
investments, is an appropriate measure for evaluating the Company's liquidity,
because this reflects all liquid resources available for strategic
opportunities including, among others, to invest in the business and continue
operating activities. However this measure should be considered in addition
to, and not as a substitute for, or superior to, cash flows prepared in
accordance with generally accepted accounting principles in the U.S.
    Under GAAP, cash flows from investing activities above would improve by
net maturities of investment securities in the amount of $0.6 million and $3.0
million for the three months ended September 30, 2005 and 2004, respectively,
and by $6.1 million for the nine months ended September 30, 2004. Also under
GAAP, cash and cash equivalents at the beginning and end of the period would
be less, as they would exclude investments of $0.6 million at June 30, 2005,
$3.0 million at September 30, 2004 and $9.1 million at December 31, 2003.
Cash, cash equivalents, short-term and long-term investments exclude
restricted cash.

    Note 2:  As part of the agreement to sell agricultural genomics assets to
Monsanto, the company committed to transition out of the agriculture industry
upon completion of its remaining contracts with DuPont or its subsidiaries.
While the company has determined that it does not yet meet the criteria to
classify its remaining activities in the agriculture industry as discontinued
operations under Statement of Financial Accounting Standards No. 144,
"Accounting for the Impairment or Disposal of Long-Lived Assets," the company
does believe these criteria will be met upon the completion of the remaining
contracts with DuPont and its subsidiaries. As included in the company's
statements of operations for the periods ended September 30, 2005 and 2004,
the company's activities related to the agriculture industry are as follows
(in thousands):



                                   Three Months Ended     Nine Months Ended
                                      September 30,          September 30,
                                       (unaudited)            (unaudited)
                                     2005       2004         2005       2004

    Revenues                       $1,552     $3,821       $8,387    $11,188
    Operating expenses:
      Research and development      1,177      3,035        5,940      9,640
      Selling, general and
       administrative                  19        169          633        549
    Total operating expenses        1,196      3,204        6,573     10,189
    Gain on sale of selected
     agricultural assets              ---        ---        4,701        ---

    Income from operations           $356       $617       $6,515       $999


    For purposes of these disclosures, the operating expenses presented above
only include those costs that are directly identifiable as relating to
agriculture activities with an allocation of facilities, information support
and employee benefits costs based on headcount.   Summarized balance sheet
information for the Company's assets related to the agriculture industry as of
September 30, 2005 is as follows (in thousands):



    Accounts receivable                                               $1,770
    Prepaid expenses                                                      18
    Total current assets                                               1,788
    Property plant & equipment, net                                      810

    Total assets                                                      $2,598

    Accounts payable                                                    $266
    Accrued liabilities                                                  447
    Deferred Revenue                                                     107
    Total current liabilities                                            820

    Deferred compensation                                                 (1)

    Total liabilities and stockholders' equity                          $819


SOURCE Icoria, Inc.




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Related links:
  • http://www.icoria.com
  • http://www.clda.com
    CONTACT:
    Media-Public Relations of Icoria, Inc.,
    +1-919-425-2999