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Quintiles Reports 3rd Quarter Net Revenue of $470.3 Million, Up 19%

    - Net income of $26.9 million

    - Cash and cash equivalents of $479 million

    RESEARCH TRIANGLE PARK, N.C., Nov. 14 /PRNewswire/ -- Quintiles
Transnational Corp. today announced financial results for the quarter ended
September 30, 2005.  Net revenue for third quarter 2005 was $470.3 million, an
increase of 19% from net revenue of $396.5 million for third quarter 2004.
Profit contribution from Quintiles' Product Development and Commercial
Services groups totaled $210.5 million in third quarter 2005, up from $193.1
million for third quarter 2004.
    Net income for third quarter 2005 was $26.9 million, after $3.4 million in
charges relating to the company's previously announced restructuring program,
compared to a net income of $34.5 million in third quarter 2004.  Quintiles'
effective income tax rate for the third quarter of 2005 was positively
impacted due to a $17.8 million income tax benefit recognized as a result of
the company's adoption of its domestic reinvestment plan related to the
American Jobs Creation Act of 2004. The net income in third quarter 2004
included an after-tax gain of $53.8 million resulting from Quintiles' sale of
certain assets relating to its Bioglan Pharmaceuticals business to Bradley
Pharmaceuticals, Inc. (NYSE: BDY) for $188 million in cash.
    Third quarter 2005 earnings before interest, taxes, depreciation and
amortization (EBITDA) totaled $58.6 million, including income from
discontinued operations net of loss on sale, before income taxes, of $300,000,
and the restructuring charge of $3.4 million.  Third quarter 2004 EBITDA was
$103.2 million, including a gain on sale net of a loss from discontinued
operations, before income taxes, of $87.3 million.  Excluding these one-time
events, EBITDA for third quarter 2005 and third quarter 2004 was,
respectively, $60.8 million and $11.3 million.  See Schedule 3 for a
reconciliation of the above amounts.
    "We are continuing to focus on the fundamentals -- providing our customers
high-quality, value-added clinical and commercialization services and
partnering solutions -- while positioning Quintiles to take advantage of the
significant potential we see in emerging markets," said Quintiles Chairman and
Chief Executive Officer Dennis Gillings, CBE.  "These strong results are
tangible evidence of the progress we're making."
    Quintiles Transnational Executive Vice President and Chief Financial
Officer John Ratliff said: "Our continued improvement in operating profits is
the result of our emphasis throughout Quintiles on driving revenue growth and
managing costs.  At the same time, we are enhancing processes to achieve
greater quality and efficiency, and we are investing in areas where we see key
opportunities for market growth and to help our customers succeed."
    As of September 30, 2005, Quintiles had cash and cash equivalents of $479
million.
    During the third quarter of 2005, Quintiles completed the sale to Aptuit,
Inc., of its Early Development and Packaging business for approximately $124
mmillion.
    After third quarter 2005 ended, Quintiles closed a financing transaction,
as previously announced, in which it raised approximately $250 million in cash
by monetizing its rights to receive royalties and certain other payments from
the U.S. sales of Eli Lilly and Company's antidepressant drug Cymbalta(R)
(duloxetine hydrochloride).  The royalty rights were part of Quintiles'
agreement with Lilly to help co-promote Cymbalta in the United States for five
years; that co-promotion agreement remains materially unchanged and Quintiles
continues to have a financial interest in the royalty rights.  Quintiles
contributed its royalty rights and certain other payment rights under the co-
promotion agreement to an indirect wholly owned subsidiary (Royalty Sub),
which issued $125 million in notes and borrowed $125 million in loans, each
secured primarily by the royalty and other payment rights.  Quintiles used a
portion of the proceeds to repay in full its outstanding term loans of $154
million under Quintiles' existing senior secured credit facility; Quintiles
plans to use the remaining cash for other purposes permitted under Quintiles'
other debt arrangements and for general corporate purposes.
    Quintiles Transnational's third quarter 2005 financial briefing will be
held at 11:00 a.m. EST on Tuesday, Nov. 15, and will be broadcast live over
the Web.  The webcast or replay, which will be available through 5:00 p.m. EST
Friday, Dec. 2, can be accessed at
http://www.quintiles.com/corporate_info/broadcast_center.
    Quintiles is the global leader in pharmaceutical services.  We improve
healthcare worldwide by providing quality professional expertise, market
intelligence and innovative partnering solutions to the pharmaceutical,
biotechnology and healthcare industries.  Quintiles has 16,000 specialized
employees and offices in 50 countries.  For more information visit the
company's Web site at http://www.quintiles.com.
    The schedules attached to this release are an integral part of this
release.  Information in this press release contains "forward looking
statements" about Quintiles.  These statements involve risks and uncertainties
that could cause actual results to differ materially, including, without
limitation, the ability to maintain large customer contracts or to enter into
new contracts, changes in trends in the pharmaceutical industry, the risk that
the market for our products and services will not grow as we expect, the risk
that our PharmaBio transactions will not generate revenue or profit at the
rate or levels we anticipate or that royalty revenues under the PharmaBio
agreements may not be adequate to offset Quintiles' upfront and ongoing
expenses in providing sales and marketing services or in making milestone and
marketing payments, our ability to fulfill our obligations under our financing
arrangements and the potential impact on our operations, our ability to
efficiently distribute backlog among project management groups and match
demand to resources, actual operating performance, variation in the actual
savings and operating improvements resulting from previous restructurings, the
ability to operate successfully in new lines of business, and the risk that,
even though Royalty Sub's notes and loans are non-recourse to Quintiles,
Quintiles may be required to make payments equal to the outstanding principal
and interest on the notes and loans in certain limited circumstances.
Additional factors that could cause actual results to differ materially are
discussed in the company's recent filings with the Securities and Exchange
Commission, including but not limited to its Annual Report on Form 10-K, its
Form 8-Ks, and its other periodic reports, including Form 10-Qs.



    Schedule 1 of 3
    Condensed Consolidated Statements of Income
    (Unaudited)

                                   Three      Three       Nine        Nine
                                   months     months     months      months
                                   ended      ended      ended       ended
                                 September  September  September   September
                                     30,        30,        30,         30,
                                    2005       2004       2005        2004

    In thousands, except per
     share data

    Net revenues                   $470,290  $396,497  $1,413,721  $1,167,020
    Add:  reimbursed service costs  141,109    91,620     377,371     251,573

    Gross revenues                  611,399   488,117   1,791,092   1,418,593

    Costs, expenses and other:
         Costs of revenues          441,497   357,888   1,285,462   1,026,055
         Selling, general and
          administrative            136,857   147,021     431,557     433,562
         Interest expense (income),
          net                        12,088    14,838      41,702      44,033
         Other expense (income),
          net                        (2,240)     (247)        423      (3,014)
         Restructuring                3,358       -        22,565         -
         Impairments                    -         -         6,633         -
         Transaction expense, net       -         -        (2,666)        -
         Gain on sale of portion
          of an investment in a
          subsidiary                    -         -           -       (24,688)
         Non-operating gain on
          change of interest
          transaction                   -         -           -       (10,030)
                                    591,560   519,500   1,785,676   1,465,918

    Income (loss) before income
     taxes                           19,839   (31,383)      5,416     (47,325)
    Income tax (benefit) expense
     (includes $17,778 and $49,299
     of income tax benefit related
     to American Jobs Creation Act
     of 2004 for the three and
     nine months ended September
     30, 2005, respectively)         (9,489)  (15,111)    (38,862)      1,729

    Income (loss) before minority
     interests and equity in
     (losses) earnings of
     unconsolidated affiliates       29,328   (16,272)     44,278     (49,054)
    Equity in (losses) earnings of
     unconsolidated affiliates         (849)     (366)     (1,377)       (389)
    Minority interests               (1,154)     (702)     (3,222)     (1,135)

    Income (loss) from continuing
     operations                      27,325   (17,340)     39,679     (50,578)

    Income (loss) from
     discontinued operations, net
     of income taxes                  4,233    (2,002)    (32,940)      5,401

    (Loss) gain from sale of
     discontinued operations, net
     of income taxes                 (4,609)   53,802      (4,609)     53,802

    Net income                      $26,949   $34,460      $2,130      $8,625



    Consolidated Balance Sheet Data
    (Unaudited)
                                              September 30,      December 31,
                                                   2005              2004
    In millions

    Cash, cash equivalents and debt
     investments                                      $493              $548
    Investments in marketable equity
     securities                                         33                24
    Investments in non-marketable equity
     securities and loans                               53                56
    Investments in unconsolidated
     affiliates                                        126               121
    Working capital                                    347               491
    Total assets                                     1,808             2,036
    Debt including current portion                     636               795
    Shareholders' equity                               543               568



    Schedule 2 of 3
    Segment Information
    (Unaudited)

                                   Three      Three       Nine        Nine
                                   months     months     months      months
                                   ended      ended      ended       ended
                                 September  September  September   September
                                     30,        30,        30,         30,
                                    2005       2004       2005        2004

    In thousands

    Service revenues:
         Product development       $279,946  $238,923    $835,777    $691,533
         Commercial services        182,680   179,126     560,063     484,972
         Eliminations               (24,319)  (26,703)    (75,963)    (41,582)
    Total net service revenues      438,307   391,346   1,319,877   1,134,923

    PharmaBio Development
         Commercial rights and
          royalties                  31,093     7,660      95,795      38,401
         Investment                     890    (2,509)     (1,951)     (6,304)
    Total PharmaBio Development      31,983     5,151      93,844      32,097

    Total net revenues              470,290   396,497   1,413,721   1,167,020
    Reimbursed service costs        141,109    91,620     377,371     251,573

    Gross revenues                 $611,399  $488,117  $1,791,092  $1,418,593


    Contribution (revenues less
     cost of revenues excluding
     depreciation and amortization
     expense except as noted
     below):
         Product development       $141,971  $121,165    $417,937    $345,530
         Commercial services         68,527    71,917     214,285     187,782
         PharmaBio Development
          (includes amortization
          and depreciation expense
          noted below)              (13,440)  (35,099)    (49,483)    (57,255)
    Total contribution             $197,058  $157,983    $582,739    $476,057


    Depreciation and amortization
     expense (excluded from
     contribution except as noted
     below):
         Product development        $17,225   $16,709     $49,716     $50,183
         Commercial services          8,743     7,857      23,887      23,864
         PharmaBio Development
          (included in
          contribution)                 376     1,121       4,609       2,940
         Corporate                    1,188     3,188       3,506       9,472
    Total depreciation and
     amortization expense           $27,532   $28,875     $81,718     $86,459



    Schedule 3 of 3
    EBITDA Reconciliation
    (Unaudited)

                                     Three      Three       Nine        Nine
                                     months     months     months      months
                                     ended      ended      ended       ended
                                   September  September  September   September
                                       30,        30,        30,         30,
                                      2005       2004       2005        2004

    In millions

    Net revenues                      $470.3     $396.5   $1,413.7   $1,167.0
    Add:  reimbursed service costs     141.1       91.6      377.4      251.6

    Gross revenues                     611.4      488.1    1,791.1    1,418.6

    Costs, expenses and other:
         Costs of revenues            (441.5)    (357.9)  (1,285.5)  (1,026.1)
         Selling, general and
          administrative              (136.9)    (147.0)    (431.6)    (433.6)
         Other (expense) income, net     2.2        0.2       (0.4)       3.0
         Impairments                     0.0        0.0       (6.6)       0.0
         Transaction expense, net        0.0        0.0        2.7        0.0
         Depreciation and amortization  27.5       28.9       81.7       86.5
         Equity in earnings (losses) of
          unconsolidated affiliates     (0.8)      (0.4)      (1.4)      (0.4)
         Minority interests             (1.2)      (0.7)      (3.2)      (1.1)
    EBITDA, excluding discontinued
     operations, restructuring charges
     and Mitsui gains                   60.8       11.3      146.8       46.9

        Income (loss) from discontinued
         operations, net of (loss)
         gain on sale                    0.3       87.3      (63.5)      92.9
        Depreciation and amortization
         from discontinued operations    0.8        4.7        8.8       16.2
        Restructuring                   (3.4)       0.0      (22.6)       0.0
        Gain on sale of portion of an
         investment in a subsidiary      0.0        0.0        0.0       24.7
        Non-operating gain on change of
         interest transaction            0.0        0.0        0.0       10.0

    EBITDA                              58.6      103.2       69.5      190.7

    Depreciation and amortization      (28.3)     (33.5)     (90.5)    (102.7)
    Interest expense, net              (12.1)     (14.8)     (41.7)     (44.0)
    Income tax benefit (expense)         8.8      (20.4)      64.8      (35.4)

    Net income                         $26.9      $34.5       $2.1       $8.6


SOURCE Quintiles Transnational Corp.




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    CONTACT:
    Pat Grebe, Media Relations,
    media.info@quintiles.com, or Greg Connors, Investor Relations,
    invest@quintiles.com, of Quintiles Transnational Corp.,
    +1-919-998-2000